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Cardiovascular dynamics during classical appetitive and aversive conditioning in laboratory primates

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Abstract

This report describes changes in the rate of rise of left and right intraventricular pressures during aversive and appetitive conditioning procedures in chair-restrained rhesus monkeys. The conditioning paradigm consisted of a one-minute tone followed, in the one case, by an electric shock, and in the other, by the delivery of Purina monkey pellets. The conditional cardiovascular response was characterized by short latency, highly significant elevations in the derivatives of both ventricular pressures as well as a marked arterial pressor response and tachycardia.

The magnitude of the conditional response to the classical aversive procedure was somewhat larger than that to appetitive conditioning. These alterations in the rate of development of intraventricular pressure can be attributed largely to augmentation in the sympathetic neural input to the heart and contribute to an analysis of selective aspects of the nervous regulation of the heart in intact, behaviorally conditioned animals.

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Authors and Affiliations

  1. Johns Hopkins University School of Medicine, Baltimore, Maryland

    D. C. Randall, J. V. Brady & K. H. Martin

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  1. D. C. Randall
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  2. J. V. Brady
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  3. K. H. Martin
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Supported by NHLI Grant HE-06945.

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Randall, D.C., Brady, J.V. & Martin, K.H. Cardiovascular dynamics during classical appetitive and aversive conditioning in laboratory primates. Pav. J. Biol. Sci. 10, 66–75 (1975). https://doi.org/10.1007/BF03001150

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