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The specificity of the Frei test in lymphopathia venera

  • Surgery Of The Lower Colon And Rectum
  • Published:
The American Journal of Digestive Diseases

Conclusion

By repeated testings the Frei test has proven specific and has assisted in the recognition of the heretofore unaccepted therapy of L.V. Over a period of two years we have observed these patients and their Frei reactions in various stages of the disease, and feel that in the presence of clinical evidence one negative test should not be considered as confirmatory that the process is not one of L.V. To a large degree, incorrect readings may be obviated by careful selection of the tissue used, strict adherence to the preparation and preservation of the antigen, its method of administration and time of reading.

We consider the Frei test to be of utmost value in the diagnosis of L.V. judging from our total series of 155 cases bearing a positive percentage of 96.7 that clinically and pathologically presented manifestations of this disease, but we do concur with Guy del Vivo (44) that further and more conclusive evidence should be sought as to its etiology.

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  1. Philadelphia, Pennsylvania

    Harry E. Bacon B.S., M.D., F.A.C.S.

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  1. Harry E. Bacon B.S., M.D., F.A.C.S.
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From the Departments of Proctology, Graduate Hospital, University of Pennsylvania, Temple University and St. Luke’s Hospitals.

Read at the thirty-sixth annual meeting of the American Proctologic Society, Atlantic City, June 10th and 11th, 1935.

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Bacon, H.E. The specificity of the Frei test in lymphopathia venera. American Journal of Digestive Diseases and Nutrition 2, 570–574 (1935). https://doi.org/10.1007/BF03000929

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