Abstract
Sodium homeostasis continues to be one of the principal areas of intense investigation in humoral physiology. This is not only because of its central role in major medical problems such as hypertension and edema. It also follows from the many intriguing problems of adaptations involving sodium control by animal species in the course of phylogenetic emergence from the oceans and irradiation into diverse ecological niches of terrestrial existence. Many of the central problems of this wide field of inquiry remain unsolved.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abraham, S., Baker, R., Denton, D., Kraintz, F., Kraintz, L. and Purser L.: Components in the regulation of salt balance: salt appetite studied by operant behaviour.Austr. J. Exp. Biol. Med. Sci.,51:65–81, 1973.
Abraham, S. F., Blair-West, J. R., Coghlan, J. P., Denton, D. A., Mouw, D. R., and Scoggins, B. A.: Aldosterone secretion in sodium deficient sheep during perfusion of the brain ventricles with high sodium CSF.Int. Res. Commun. Syst.,3, 1973.
Beilharz, S., Bott, E., Denton, D. A., and Sabine, J. R.: The effect of intra-carotid infusions of 4 M-NaCl on the sodium drinking of sheep with a parotid fistula.J. Physiol.,178:80–91, 1965.
Blair-West, J. R., Boyd, G. W., Coghlan, J. P., Denton, D. A., Goding, J. R., Wintour, E. M., and Wright, R. D.: Aldosterone secretion in relation to homeostasis of body fluids. Proc. XXIII Int. Congr. Physiol. Sci., Tokyo, Int. Congr. Series87,Excerpta Medica, 207–221, 1965.
Blair-West, J. R., and Brook, A. H.: Circulatory changes and renin secretion in sheep in response to feeding.J. Physiol.,204:15–30, 1969.
Blair-West, J. R., Coghlan, J. P., Denton, D. A., Funder, J. W., Scoggins, B. A., and Wright, R. D.: The effect of adrenal arterial infusion of hypertonic NaHCO3 solution on aldosterone secretion in sodium deficient sheep.Acta Endocrinol. 66:448–461, 1971.
Blair-West, J. R., Coghlan, J. P., Denton, D. A., Nelson, J. F., Orchard, E., Scoggins, B. A., Wright, R. D., Myers, K., and Junqueira, C. L.: Physiological, morphological and behavioural adaptation to a sodium deficient environment by wild native Australian and introduced species of animals.Nature 217:922–928, 1968.
Blair-West, J. R., Coghlan, J. P., Denton, D. A., and Scoggins, B. A.: Aldosterone control—a fifth factor?Proc. 25thInt. Congr. Physiol. Sci. Munich,9:1806, 1971.
Coghlan, J. P., Blair-West, J. R., Denton, D. A., Scoggins, B. A., and Wright, R. D.: Perspectives in aldosterone and renin control.Aust. N. Z.J. Med.,1:178–197, 1971.
Denton, D. A.: Evolutionary aspects of the emergence of aldosterone secretion and salt appetite.Physiol. Rev.,45:245–295, 1965.
Denton, D. A.: Some theoretical considerations in relation to innate appetite for salt.Cond. Reflex,1:144–170, 1966.
Denton, D. A., and Nelson, J. F.: The effect of deoxycorticosterone, acetate and aldosterone on the salt appetite of wild rabbits (Oryctolagus Cuniculus, L).Endocrinology,87:970–977, 1970.
Denton, D. A., Nelson, J. F., Orchard, E., and Weiler, S.: The role of adrenocortical hormone secretion in salt appetite. Olfaction and Taste. Rocke-feller University Press, New York, 535–547, 1969.
Denton, D. A., Orchard, E., and Weller, S.: The effect of rapid change of sodium balance and expansion of plasma volume on sodium appetite of sodium deficient sheep.Commun. Behav. Biol.,6:245–258, 1971.
Denton, D. A., Orchard, E., and Weller, S.: The relation between voluntary sodium intake and body sodium balance in normal and adrenalectomized sheep.Commun. Behav. Eiol.,3:213–221, 1969.
Fitzsimons, T. J., and Le Magnen, J.: Eating as a regulatory control of drinking in the rat.J. Comp Physiol. Psychol,67:273, 1969.
Hogg, G.: Cannibalism and Human Sacrifice. Robert Hale Ltd., London, 1958.
Pappenheimer, J. R., Heisey, S. R., Jordan, E. F., and Downer, J. C.: Perfusion of the cerebral ventricular system in unanaesthetized goats.Am. J. Physiol.,203:763, 1962.
Richter, C. P.: Nutritional requirement of pregnant and lactating rats studied by the self-selection method.Endocrinology,23:15, 1938.
Schaller, G. B.: The Mountain Gorilla. The University of Chicago Press, Chicago, 1963.
Shulkes, A. A., Covelli, M. D., Denton, D. A., and Nelson, J. F.: Hormonal factors influencing salt appetite in lactation.Austr. J. Exp. Biol. Med. Sci.,50:819–826, 1972.
Underwood, E. J.: The Mineral Nutrition of Livestock. Commonwealth Agricultural Bureaux, 1966.
van Lawick-Goodall, J.: My Friends the Wild Chimpanzees. National Geographic Society, Washington, 1967.
Weir, J. S.: Spatial distribution of elephants in an African national park in relation to environmental sodium.Oikos,23:1–13, 1972.
Wolf, G.: Olfaction and Taste III, The Rockefeller University Press, New York, 1969.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Denton, D.A. The brain and sodium homeostasis. Conditional Reflex 8, 125–146 (1973). https://doi.org/10.1007/BF03000494
Issue Date:
DOI: https://doi.org/10.1007/BF03000494