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Cardiac pacing and the law of initial value in rhesus monkeys

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Abstract

A cardiac pacemaker was used to produce a wide range of pre-CS heart rates in Pavlovian conditioning, and correlations were computed between pre-CS and CS heart rates. Two rhesus monkeys were presented trials in which 30 sec of light (CS) was followed by a brief electric shock (UCS). Pacing rates during the inter-trial intervals were varied from 150 to 350 bpm. Pacing was discontinued during CS. Unpaced control sessions showed that the maximum heart rate in CS on each trial was proportional to the pre-CS heart rate. Following pacing, however, heart rate in CS did not depend on the pacing rate; rather, the rates were not different from those of the unpaced control sessions. Pacing at high rates shifted the maximum heart rate toward the end of CS.

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Supported by Grant MH 13049 from the National Institute of Mental Health, U. S. Public Health Service, and in part by the Veterans Administration. Reprints may be obtained from the Psychology Research Laboratory, FDR VA Hospital, Montrose, New York 10548.

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Snapper, A.G., Kadden, R.M. & Schoenfeld, W.N. Cardiac pacing and the law of initial value in rhesus monkeys. Conditional Reflex 6, 227–235 (1971). https://doi.org/10.1007/BF03000457

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