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Production of peptic ulcers in rats and mice by diets deficient in protein

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The American Journal of Digestive Diseases

Summary

Ulceration of the prostomach and main stomach of rats and mice and ulceration of the duodenum of mice but not of rats was found to occur as a result of starvation or diets deficient in protein or in essential amino-acids.

Ulceration thus produced is regarded as objective evidence of protein-hunger or amino-acid-hunger which has been carried to a pathologic extreme.

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Authors and Affiliations

  1. Chicago, Illinois

    Frederick Hoelzel & Esther Da Costa M.S.

Authors
  1. Frederick Hoelzel
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  2. Esther Da Costa M.S.
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From the Department of Physiology, University of Chicago.

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Hoelzel, F., Da Costa, E. Production of peptic ulcers in rats and mice by diets deficient in protein. American Journal of Digestive Diseases and Nutrition 4, 325–331 (1937). https://doi.org/10.1007/BF02999927

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  • DOI: https://doi.org/10.1007/BF02999927

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