Summary and Conclusions
Experimental and clinical evidence is cited which seems to demonstrate: (1) the occurrence of fatty degeneration of the liver when there is extensive destruction of the pancreas, (2) that the absence of the hormonal substance, lipocaic, may be the inciting factor for these changes in the liver, and (3) that there may be some therapeutic use for this preparation in certain clinical cases of pancreatic disease. If this is not available, the feeding of raw pancreas and diets high in lecithin is suggested. The possible relation of fatty change to the later development of cirrhosis invites speculation.
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Snell, A.M., Comfort, M.W. Hepatic lesions presumably secondary to pancreatic lithiasis and atrophy; report of two cases. American Journal of Digestive Diseases and Nutrition 4, 215–218 (1937). https://doi.org/10.1007/BF02999899
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DOI: https://doi.org/10.1007/BF02999899