Skip to main content
SpringerLink
Log in

The bioelectrical activity of cerebellar structures in the freely-moving rat

  • Published:
Integrative Psychological and Behavioral Science Aims and scope Submit manuscript

Abstract

Electrodes were implanted in the brains of 27 freelymoving rats and the bioelectrical activity of cerebellar cortical structures (lobus simplex, tuber verrais, lobus ansiformis, crus II) and the dentate nucleus was measured simultaneously with the activity of the cerebral cortex and dorsal hippocampus and respiratory rate and motor activity. Different behavioral states were produced by habituation procedures and by elaborating conditional avoidance reflexes to light-flash or click series. In addition, startle reflexes to acoustic stimuli were used to evaluate behavioral state.

The following conclusions could be drawn: 1) in the awake rat the various cerebellar structures have clearly distinguishable bioelectrical activity patterns; 2) changes in these patterns depend on the actual behavioral state of the animal; 3) this dependence upon behavior is especially clear in crus II, one of the projection zones of the tactile and proprioceptive afferent nerves in the cerebellar cortex.

The changes in the electrocerebellogram of the unrestrained rat may be used as an indicator of the behavioral state of the animal.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Adrian, E. D.: Discharge frequencies in the cerebral and cerebellar cortex.J. Physiol. (London),83: 32P-33P, 1935.

    Google Scholar 

  • Brookhart, J. M.: The cerebellum.In: Field, J. (ed.):Handbook of Physiology. Section 1, Neurophysiology, Vol.II. Washington, American Physiology Society, 1960, pp. 1245–1280.

    Google Scholar 

  • Brookhart, J. M., Moruzzi, G., and Snider, R. S.: Origin of cerebellar waves.J. Neurophysiol.,14: 181–190, 1951.

    PubMed  Google Scholar 

  • Crepax, P., and Infantellina, F.: L’attività elettrica del lembo isolato di corteccia cerebellare di gatto.Boll. Soc. Ital. Biol. Sper.,31: 1229–1231, 1955.

    PubMed  Google Scholar 

  • Crepax, P., and Infantellina, F.: Il preparato di lembo isolato di corteccia cerebellare di gatto.Arch. Sci. Biol. (Bologna),41: 57–73, 1957.

    Google Scholar 

  • Dow, R. S., and Moruzzi, G.: The Physiology and Pathology of the Cerebellum. Minneapolis, University of Minnesota Press, 1958, 675 pp.

    Google Scholar 

  • Irger, I. M., Koreischa, L. A., and Tolmasskaja, E. S.: Voprosy nejrochirurgii,5: 34–38, 1949 (Russ.).

    Google Scholar 

  • Irger, I. M., Koreischa, L. A., and Tolmasskaja, E. S.: (Untersuchungen über die elektrische Aktivität phylogenetisch unterschiedlicher Teile des Kleinhirns beim Menschen und bei Tieren.)Fiziol. Z. SSSR,37: 273–282, 1951 (Russ.).

    Google Scholar 

  • Klingberg, F., and Pickenhain, L.: Veränderungen des ECG, der kortikalen hervorgerufenen Potentiale und der Startle-Reaktionen bei Ratten während der Ausarbeitung eines bedingten Fluchtreflexes.Acta Biol. Med. German.,12: 552–567, 1964.

    PubMed  Google Scholar 

  • Klingberg, F., and Pickenhain, L.: Über die Beteiligung des Hippokampus an der Ausarbeitung eines bedingten Fluchtreflexes bei der Ratte.Acta Physiol. Acad. Sci. Hungar.,27: 359–374, 1965a.

    Google Scholar 

  • Klingberg, F., and Pickenhain, L.: Elektrophysiologische und Verhaltensuntersuchungen über die Ausarbeitung eines bedingten Abwehrreflexes auf elektrische Reize ohne Fluchtmöglichkeit bei Ratten.Acta Biol. Med. German.,14: 749–763, 1965b.

    PubMed  Google Scholar 

  • Klingberg, F., and Pickenhain, L.: Über induzierte Salven im Bulbus olfactorius der Ratte und ihre Beziehung zum Verhalten des Tieres.Acta Biol. Med. German.,15: 58–70, 1965c.

    Google Scholar 

  • Klingberg, F., and Pickenhain, L.: Das Auftreten kortikaler Nachentladungen als Indikator für den Verhaltenszustand des Tieres.Wiss. Z. Karl-Marx-Univers. Leipzig,15: 533–539, 1966.

    Google Scholar 

  • Klingberg, F., and Pickenhain, L.: Der Einfluss des Verhaltens auf die photisch ausgelöste Rekrutierung.Acta Biol. Med. German.,19: 267–283, 1967.

    PubMed  Google Scholar 

  • Klingberg, F., and Pickenhain, L.: Das Auftreten von “Spindelentladungen” bei der Ratte in Beziehung zum Verhalten.Acta Biol. Med. German.,20: 45–54, 1968.

    PubMed  Google Scholar 

  • Klingberg, F., Pickenhain, L., and Gelbrich, D.: Registrierung der Atmung bei der frei beweglichen Ratte im chronischen elektrophysiologischen Experiment.Acta Biol. Med. German.,12: 619–622, 1964.

    PubMed  Google Scholar 

  • Klingberg, F., Pickenhain, L., and Sakano, N.: Beziehungen zwischen der motorischen Reaktionsbereitschaft der Ratte und dem Startle-Reflex.Acta Physiol. Acad. Sci. Hungar.,29: 261–266, 1966.

    Google Scholar 

  • Kullanda, K. M.: (Elektrische Erscheinungen in der Kleinhirnrinde.) in: Sovremennye problemy elektrofiziologičeskich issledovanij nervnoj sistemy. Moscow, 1964, 333–360 (Russ.).

  • Larsell, O.: The morphogenesis and adult pattern of the lobules and fissures of the cerebellum in the white ratJ. Comp. Neurol.,97: 281–356, 1952.

    Article  PubMed  Google Scholar 

  • Lifschitz, W.: Changes in cerebellar electrical activity during the development of conditioned reflexes.J. Physiol., London,159: 29P-30P, 1961.

    Google Scholar 

  • Pickenhain, L., and Klingberg, F.: Behavioral and electrophysiological changes during avoidance conditioning to light flashes in rat.Electroenceph. Clin. Neurophysiol.,18: 464–476, 1965.

    Article  PubMed  Google Scholar 

  • Pickenhain, L., and Klingberg, F.: Charakterisierung unterschiedlicher Stadien des Wachzustandes bei der Ratte durch elektrophysiologische und Verhaltensdaten.Acta Physiol. Acad. Sci. Hungar.,29: 253–260, 1966.

    Google Scholar 

  • Pickenhain, L., and Klingberg, F.: Hippocampal slow wave activity as a correlate of basic behavioral mechanisms in rat. In: Progress in Brain Research. Vol. 27, Structure and Function of the Limbic System, 1967a, pp. 218–227.

  • Pickenhain, L., and Klingberg, F.: Electrophysiological and behavioral investigations on the delay period of conditioned reflexes, In: Recent Development of Neurobiology in Hungary. Vol. 1: lissák, K. (ed.): Results in Neuroanatomy, Neurochemistry, Neuropharmacology and Neurophysiology, 1967b, pp. 98–120.

  • Pickenhain, L., and Klingberg, F.: Hirnmechanismen und Verhalten.In: J. Bures, G. Kostjuk, E. Roy John and L. Pickenhain (Hrg.), Abhandlungen aus dem Gebiet der Hirnforschung und Verhaltensphysiologie, Bd. 2, VEB G. Fischer V. Jena, 1968, 256 pp.

  • Rétif, J.: Ètude de l’activité électrique spontanée du cervelet humain.Acta Neurol. Psychiat. Belg.,64: 825–831, 1964.

    Google Scholar 

  • Snider, R. S., and Eldred, E.: Maintenance of spontaneous activity within the cerebellum.Proc. Soc. Exp. Biol. Med.,72: 124–127, 1949.

    PubMed  Google Scholar 

  • Szabó, I., Kellényi, L., and Karmos, G.: A simple device for recording movements of unrestrained animals.Acta Physiol. Acad. Sci. Hungar.,26: 343–349, 1965.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Leipzig, German Democratic Republic

    J. Oehler, L. Pickenhain & F. Klingberg

Authors
  1. J. Oehler
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Pickenhain
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. F. Klingberg
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Revision of a paper delivered at the Third Annual Meeting of the Pavlovian Society of North America, Baltimore, Maryland, September 6, 1968.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Oehler, J., Pickenhain, L. & Klingberg, F. The bioelectrical activity of cerebellar structures in the freely-moving rat. Integr. psych. behav. 4, 187–198 (1969). https://doi.org/10.1007/BF02999657

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02999657

Keywords

Search

Navigation