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Studies on the chemical nature of the interaction between the intrinsic and extrinsic antianemic factors upon incubation of liver extract and normal gastric juice

  • Experimental Physiology
  • Published:
The American Journal of Digestive Diseases

Summary

Attempts have been made to determine the chemical change occurring as a result of incubation together of liver extract and normal gastric juice at pH 2.0, 5.6 and 8.0. The chemical constituents of liver extract which were studied were the carboxyl groups, amino nitrogen, and soluble nitrogen after precipitation with trichloracetic acid.

No significant chemical changes were noted in this series of experiments except for those associated with a slight proteolytic effect at pH 2.0, attributable to peptic activity.

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References

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Authors and Affiliations

  1. Indianapolis, Indiana

    O. M. Helmer Ph.D. & Charles P. Emerson B.S.

Authors
  1. O. M. Helmer Ph.D.
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  2. Charles P. Emerson B.S.
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Additional information

From the Lilly Laboratory for Clinical Research, Indianapolis City Hospital, Indianapolis, Indiana.

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Helmer, O.M., Emerson, C.P. Studies on the chemical nature of the interaction between the intrinsic and extrinsic antianemic factors upon incubation of liver extract and normal gastric juice. American Journal of Digestive Diseases and Nutrition 3, 906–908 (1936). https://doi.org/10.1007/BF02999293

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  • DOI: https://doi.org/10.1007/BF02999293

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