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Cholesterol metabolism in jaundice

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The American Journal of Digestive Diseases

Summary

In obstructive jaundice blood cholesterol rises while bile cholesterol is normal or low depending on the completeness of the obstruction and its duration.

In obstructive jaundice with liver infection, both blood and bile cholesterol are low.

In toxic jaundice the blood cholesterol is normal or low depending on the severity of the disease. Bile cholesterol is uniformly low and remains low after the condition has apparently cleared up.

Hyperthyroidism causes an elevation of bile cholesterol approximately in proportion to the depression of blood cholesterol.

Myxedema produces a low bile cholesterol and a proportionate elevation of blood cholesterol.

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From the Gastro-Enterological Department of the Lahey Clinic, Boston. Delivered (by invitation) at the Thirty-Ninth Annual Session of the American Gastro-Enterological Association, Atlantic City, N. J., May 4–5, 1936.

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Wilkinson, S.A. Cholesterol metabolism in jaundice. American Journal of Digestive Diseases and Nutrition 3, 618–622 (1936). https://doi.org/10.1007/BF02999178

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  • DOI: https://doi.org/10.1007/BF02999178

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