Skip to main content
Log in

Aluminum hydroxide as an antacid in peptic ulcer

  • Therapeutics
  • Published:
The American Journal of Digestive Diseases

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Roch, M.: Comptes Rendus.Congres Francais de medecine, Paris, p. 101, 1922, (quoted by Kagan, see reference 3).

  2. Guillermin, R.: Hyperchlorhydria et hydrate d’aluminum colloidal.Revue med. de la Suisse rom., 44:243–246, April, 1924.

    Google Scholar 

  3. Kagan, S. R.: The treatment of gastric ulcer and hyperchlorhydria.Clin. Med., 32:229–235, April, 1925.

    Google Scholar 

  4. Crohn, B. B.: The clinical use of colloidal aluminum hydroxide as a gastric antacid.J. Lab. Clin. Med., 14:610–614, April, 1929.

    CAS  Google Scholar 

  5. Kreis, L.: Kausale Radikalheilung der Hyperazidität dur konservative Behandlung.Wien. Med. Woch., 81:140, Jan. 24, 1931.

    Google Scholar 

  6. Einsel, I. H., Adams, W. L., and Myers, V. C.: Aluminum Hydroxide in the Treatment of Peptic Ulcer.Trans. Am. Gastro-Enterolog. Assn., 37:89–92, 1934;Am. J. Dig. Dis. and Nutrition, 1:513–516, Sept., 1934.

    Google Scholar 

  7. Unpublished data presented before the Experimental Medicine Section of the Cleveland Academy of Medicine, Dec., 1930.

  8. Myers, V. C., Mull, J. W., and Morrison, D. B.: The Estimation of Aluminum in Animal Tissues.J. Biol. Chem., 78:595–604, August, 1928.

    CAS  Google Scholar 

  9. Einsel, I. H., and Rowland, V. C.: The Aluminum Hydroxide Treatment of Peptic Ulcer.Ohio State Med. J., 28:173–174, March, 1932.

    Google Scholar 

  10. Myers, V. C., and Muntwyler, E.: The Colorimetric Estimation of the Hydrogen ion Concentration of Blood.J. Biol. Chem., 78:243–253, June, 1928.

    CAS  Google Scholar 

  11. Wilson, D., and Ball, E. G.: A Study of the Estimation of Chloride in Blood Serum.J. Biol. Chem., 79:221–227, Sept., 1928.

    CAS  Google Scholar 

  12. Stadie, W. C., and Ross, E. C.: A Micro Method for the Determination of Base in Blood and Serum and other Biological Materials.J. Biol. Chem., 65:735–754, Oct., 1925.

    CAS  Google Scholar 

  13. Wright, S. L., and Allison, C. L.: The Determination of Total Base.J. Biol. Chem., 100:1–11, March, 1933.

    CAS  Google Scholar 

  14. Helmer, O. M., Fouts, P. J., and Zerfas, L. G.: Gastro-Intestinal Studies. I. Gastric juice in pernicious anemia.J. Clin. Invest., 11:1129–1153, Nov., 1932.

    Article  PubMed  CAS  Google Scholar 

  15. Van Slyke, D. D., and Cullen, G. E.: Studies of Acidosis. I. The bicarbonate concentration of the blood plasma: its significance and its determination as a measure of acidosis.J. Biol. Chem., 30:289–346, 1917.

    Google Scholar 

  16. Bloomfield, A. L., and Keefer, C. S.: Gastric Motility and the Volume of Gastric Secretion in Man.J. Clin. Invest., 5:295–301, Feb., 1928.

    Article  PubMed  CAS  Google Scholar 

  17. Berglund, H., Wahlquist, H., and Sherwood, K. K.: Hydrochloric Acid and Total Chlorine Content of Pure Gastric Juice Produced after Histamine Injection.Proc. Soc. Exp. Biol. and Med., 24:927–929, June, 1927.

    Google Scholar 

  18. Polland, W. S., Roberts, A. M., and Bloomfield, A. L.: The Chloride, Base and Nitrogen Content of Gastric Juice after Histamine Stimulation.J. Clin. Invest., 5:611–637, June, 1928.

    Article  PubMed  CAS  Google Scholar 

  19. Bulgar, H. A., Stroud, C. M., and Heideman, M. L.: Electrolyte Variations in Human Gastric Juice.J. Clin. Invest., 5:547–560, June, 1928.

    Article  Google Scholar 

  20. Austin, J. H., and Gammon, G. D.: Gastric Secretion after Histamine. Sodium and Potassium Content and Pepsin Estimation.J. Clin. Invest., 10:287–307, June, 1931.

    Article  PubMed  CAS  Google Scholar 

  21. Gatewood, W. E., Gaebler, O. H., Muntwyler, E., and Myers, V. C.: Alkalosis in Patients with Peptic Ulcer.Arch. Int. Med., 42:79–105, July, 1928.

    CAS  Google Scholar 

  22. Wildman, H. A.: Chloride Metabolism and Alkalosis in Alkali Treatment of Peptic Ulcer.Arch. Int. Med., 43:615–632, May, 1929.

    Google Scholar 

  23. Myers, V. C., and Killian, J. A.: The Solubility in the Stomach and Duodenum of Aluminum Compounds Found in Baking Powder Residues.J. Biol. Chem., 78:519–594, August, 1928.

    Google Scholar 

  24. Myers, V. C., and Mull, J. W.: The Influence of the Administration of Aluminum upon the Aluminum Content of the Tissues, and upon the Growth and Reproduction of Rats.J. Biol. Chem., 78:605–613, August, 1928.

    CAS  Google Scholar 

  25. Myers, V. C., and Morrison, D. B.: The Influence of the Administration of Aluminum upon the Aluminum Content of the Tissues of the Dog.J. Biol. Chem., 78:615–624, August, 1928, also Eveleth D. F., and Myers, V. C.: Studies on Aluminum. II. The Storage of Intravenously Injected Aluminum in the Dog.J. Biol. Chem., 113:467–471, March, 1936.

    CAS  Google Scholar 

  26. Wührer, J.: Zur Frage der Resorption von Aluminumverbindungen im Organismus, mit Berucksichtigung des normalen Aluminumgehalt terischer Gewebe.Biochem. Z., 265:169–180, 1933.

    Google Scholar 

  27. Dodds, E. C., and Smith, K. S.: Variations in the Blood Chlorides in Relation to Meals.J. Physiol., 58:157–162, Dec. 28, 1923.

    PubMed  CAS  Google Scholar 

  28. Gram, H. C.: Chlorides of Serum, Blood and Corpuscles in Various Pathological Conditions.J. Biol. Chem., 61:337–343, Sept., 1924.

    CAS  Google Scholar 

  29. Arnoldi, W.: Ueber Aenderungen des Chlorgehalts im Blutserum bei Sekretionsstorungen des Magens.Zeit. klin. Med., 76:45–56, 1912.

    Google Scholar 

  30. Molnar, B., Jr., and Hetenyi, G.: Ueber den Chlorgehalt des Blutserums bei Sekretionsstorungen des Magens und Beinflussing der Anazidität durch Kochsalz.Arch. f. Verdauungskr., 30:8–12, 1922.

    Article  CAS  Google Scholar 

  31. Lim, R. K. S., and Ni, T. S.: Changes in Blood Constituents Accompanying Gastric Secretion. I. Chlorides.Am. J. Physiol., 75:475–486, Jan., 1926.

    Google Scholar 

  32. Jordan, S. M.: Calcium, Chloride and Carbon Dioxide Content of Venous Blood in Cases of Gastroduodenal Ulcer Treated with Alkalis.J. Am. Med. Assoc., 87:1906–1909, Dec. 4, 1926.

    CAS  Google Scholar 

  33. Bloch, L., and Serby, A. M.: Plasma and Corpuscular Chlorides in Peptic Ulcer.Arch. Int. Med., 41:415–419, March, 1928.

    CAS  Google Scholar 

  34. Sunderman, F. W.: The Total Base and Protein Components of the Serum During Lobar Pneumonia with a Note on the Gastric Secretion.J. Clin. Invest., 9:615–633, Feb., 1931.

    Article  PubMed  CAS  Google Scholar 

  35. Myers, V. C., and Booher, L. E.: Some Variations in the Acid-Base Balance of the Blood in Disease.J. Biol. Chem., 59:699–712, April, 1924.

    CAS  Google Scholar 

  36. Hiestand, R. F., and Hall, J. L.: Effect of Histamine on Alkali Reserve and on Blood Sugar in Man.Arch. Int. Med., 49:799–807, May, 1932.

    CAS  Google Scholar 

  37. Katzenelbogen, S.: The Action of Histamine on the Alkali Reserve.J. Am. Med. Assoc., 92:1240–1241, April 13, 1929.

    CAS  Google Scholar 

  38. Neale, A. V., and Klumpp, T. G.: Action of Histamine on the Pancreas.J. Clin. Invest., 9:197–208, Oct., 1930.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

From the Departments of Biochemistry and Medicine (City Hospital Service), School of Medicine, Western Reserve University, Cleveland.

The data presented in this paper are taken from the dissertation submitted by W. Lloyd Adams to the Graduate School of Western Rements University, June 1933, in partial fulfillment of the requirements of the degree of Doctor of Philosophy.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lloyd Adams, W., Einsel, I.H. & Myers, V.C. Aluminum hydroxide as an antacid in peptic ulcer. American Journal of Digestive Diseases and Nutrition 3, 112–120 (1936). https://doi.org/10.1007/BF02999073

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02999073

Keywords

Navigation