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Gastric ulcers associated with cinchophen poisoning

Report of an Instance with consideration of the possible etiologic relationship

  • Clinical Medicine
  • Published:
The American Journal of Digestive Diseases

Summary

An instance of cinchophen poisoning associated with gastric ulcers is reported and another case is collected from the literature. The probability of cinchophen acting as the etiologic agent is suggested and discussed. Attention is directed to the need of further clinical and roentgenologic studies of the stomach and duodenum of patients who exhibit cinchophen poisoning. It is suggested that a carefulanamnesis in all peptic ulcer patients from the stand-point of cinchophen therapy might yield interesting data.

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References

  1. Van Wagoner, F. H., and Churchill, T. P.: Production of Gastric and Duodenal Ulcers in Experimental Cinchophen Poisoning of Dogs.Arch. Path. 14: 860; (Dec.) 1932. Churchill, T. P., and Van Wagoner, F. H.: Cinchophen Poisoning,Proc. Soc. Exper. Biol. and Med. 28; 581; (March) 1931.

    Google Scholar 

  2. Barbour, H. G., and Fisk, M. E.: Liver Damage in Dogs and Rats after Repeated Oral Administration of Cinchophen, Ethyl Ester of Paramethylphenylcinchoninic Acid (Tolysin) and Sodium Salicylate,J. Pharm. and Exper. Therap. 48; 341; (July) 1933.

    CAS  Google Scholar 

  3. Reah, T. G.: Cinchophen Poisoning.Lancet 2: 504: (Sept. 3), 1932.

    Article  Google Scholar 

  4. Rabinowitz, M. A.: Atrophy of the Liver Due to Cinchophen Preparations,Jour. A. M. A. 95; 1228; (Oct. 25), 1930.

    Google Scholar 

  5. Quick, A. J.: The Probable Allergic Nature of Cinchophen Poisoning. With Special Reference to the Arthus Phenomenon and with Precautions to be Followed in Cinchophen Administration,Am. J. Med. Sc. 187; 115; (Jan.) 1934.

    Article  Google Scholar 

  6. Opie, E. L.: Inflammatory Reaction of the Immune Animal to Antigen and Its Relation to Antibodies.J. Immunol 9; 231: (July) 1924.

    CAS  Google Scholar 

  7. Auer, J.: Local Auto-inoculation of the Sensitized Organism with Foreign Protein as a Cause of Abnormal Reactions,J. Exper. Med. 32; 427; (Oct.) 1920.

    Article  Google Scholar 

  8. Shapiro, P. F., and Ivy, A. C.: Gastric Ulcer. Experimental Production of Gastric Ulcer by Local Anaphylaxis,Arch. Int. Med. 38; 237; (Aug.) 1926.

    CAS  Google Scholar 

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From the Departments of Medicine and Pathology, Michael Reese Hospital, Chicago, Illinois.

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Bloch, L., Rosenberg, D.H. Gastric ulcers associated with cinchophen poisoning. American Journal of Digestive Diseases and Nutrition 1, 29–31 (1934). https://doi.org/10.1007/BF02998976

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  • DOI: https://doi.org/10.1007/BF02998976

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