The American Journal of Digestive Diseases

, Volume 12, Issue 8, pp 272–276 | Cite as

Allergy as a factor in surface ulcers, varicose veins, phlebitis and thrombosis

  • John A. Turnbull


  1. 1.

    The causes and symptoms of varicose veins, together with their sequelae, varicose ulcer, thrombosis and phlebitis, are reviewed.

  2. 2.

    Attention is called to the fact that

  1. a)

    most of these conditions occur most frequently in the legs, but

  2. b)

    thrombosis, in particular, while it has been observed in all parts of the body, is more frequent in the coronary and femoral arteries.

  1. 3.

    Allergenic foods and other substances may produce inflammation and other reactions in the endothelium of the blood vessels, in the same way that they produce the more familiar sensitizations of the epithelium.

  2. 4.

    Six cases are cited: 2 had pruritis and eczema; 3 had varicose ulcers of the leg, 1 of the neck; 2 had angina pectoris, showing involvement of the coronary arteries; there were 2 case’s of thrombosis of the femoral vessels.

  3. 5.

    In each of the cases described, complete relief of symptoms was obtained by adherence to diets based on avoidance of allergenic foods, as demonstrated by cutaneous tests. In Cases 1, 5 and 6, lapses from the prescribed diet brought on recurrence of symptoms.



Ulcer Healing Allergenic Food Varicose Vein Sulfanilamide Phlebitis 
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  1. 1.
    Aschoff, Ludwig: “Thrombosis”, Arch. Int. Med. XII, p. 503, Nov. 1913.Google Scholar
  2. 2.
    Dietrich, A.: “Wesen und Bedingungen der Thrombose und Embolie”, Klin. Wchnschr. X, p. 54, Jan. 10, 1931.CrossRefGoogle Scholar
  3. 3.
    Pfleiderer, “Zur Emboliefrage”, Munch, med. Wchnschr. LXXV, p. 859, May 18, 1928.Google Scholar
  4. 4.
    Knepper, R. and Waaler, G.: “Hyperergische Ateritis der Kranz-und Lungengefasse bei funktioneller Belastung”, Virchow’s Archiv f. path. Anat, u. Physiol., CCXCIV p. 587, 1935.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1945

Authors and Affiliations

  • John A. Turnbull
    • 1
  1. 1.Boston

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