Some effects of magnesium trisilicate ingestion upon blood, urine, and feces of human subjects

Conclusions

• 1. The effect of ingesting 6 grams of hydrated magnesium trisilicate daily for periods of several days upon urine and blood magnesium and calcium, urine pH and titratable acidity, feces pH, and the absorption of carbohydrates, fats and proteins in humans has been studied.

• 2. Serum calcium was slightly decreased, and urinary calcium was unchanged.

• 3. Serum magnesium levels were generally definitely, and in some cases markedly increased, with resultant drowsiness. Urinary magnesium was increased an average of 56 percent.

• 4. Urinary pH was increased an average of about 8 percent, and titratable acidity was decreased 34 percent. Feces pH was increased 5.5 percent.

• 5. The utilization of carbohydrates and fats was essentially unchanged. Protein absorption was decreased and represented the loss of 6-10 percent of dietary protein.

• 6. An average of about 6.5 percent of the magnesium content of trisilicate ingested was absorbed and excreted in the urine. This was markedly increased by increased acidification of the gastro-intestinal tract.