Summary
A case is presented of purpura due to hypoprothrombinemia in a patient suffering from anorexia nervosa. The abnormal bleeding state was cured by the administration of Vitamin K.
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Minot, G. R.: Three Cases of Chronic Dietary Deficiency.Med. Clin. No. Amer., 16:761, 1933.
Quick, A. J., Stanley-Brown, M. and Bancroft, F. W.: Study of Coagulation Defect in Hemophilia and Jaundice.Am. J. Med. Sci., 190:501, 1935.
Warner, E. D., Brinkhous, K. M. and Smith, H. P.: Quantitative Study on Blood Clotting: Prothrombin Fluctuations Under Experimental Conditions.Am. J. Physiol., 114:667, 1936.
Aggeler, P. M., Lucia, S. P. and Goldman, L.: Effect of Synthetic Vitamin K Compounds on the Prothrombin Concentration in Man.Proe. Soe. Exper. Biol. and Med., 43:689, 1940.
Aggeler, P. M. and Lucia, S. P. : The Bleeding Tendency in Diseases of the Liver and Biliary Passages. Acta Med. Scand., 107: fasc. III-V, 1941.
Lucia, S. P. and Aggeler, P. M.: The Influence of Liver Damage on the Plasma Prothrombin Concentration and Response to Vitamin K.Am. J. Med. Sci., 201:326, 1941.
Sweet, N. J., Lucia, S. P. and Aggeler, P. M.: A Clinico-Pathological Correlation Between Hepatic Damage and the Plasma Prothrombin Concentration.Am. J. Med. Sci., 203:665, 1942.
Warner, E. D., Brinkhous, K. M. and Smith, H. P.: Bleeding Tendency in Obstructive Jaundice: Prothrombin Deficiency and Dietary Factors.Proc. Soc. Exp. Biol. and Med., 37:628, 1938.
Brinkhous, K. M., Smith, H. P. and Warner, E. D.: Prothrombin Deficiency and the Bleeding Tendency in Obstructive Jaundice and in Biliary Fistula.Am. J. Med. Sci., 196:50, 1938.
Butt, H. R., Snell, A. M. and Osterberg, A. E.: Phthiocol, Its Therapeutic Effect in the Treatment of Hypoprothrombinemia Associated with Jaundice : A Preliminary Report. Proc. Staff Meet. Mayo Clinic, 14:497, 1939.
Butt, H. R., Snell, A. M. and Osterberg, A. E.: Pre-Operative and Post-Operative Administration of Vitamin K.J. A. M. A.,113:383, 1939.
Clark, R. L., Jr., Dixon, C. F., Butt, H. R. and Snell, A. M.: Deficiency of Prothrombin Associated with Various Intestinal Disorders : Its Treatment with Antihemorrhagie Vitamin (Vitamin K.) Proc. Staff Meet. Mayo Clinic, 14:407, 1939.
Weir, J. F., Butt, H. R. and Snell, A. M.: Further Observations on the Clinical Use of Vitamin K.Am. J. Dig. Dis., 7:486, 1940.
Rhoads, J. E.: The Relation of Vitamin K to Hemorrhagic Tendency in Obstructive Jaundice, with a Report on Cerophyl as a Source of Vitamin K.Surgery, 5 :794, 1939.
Rhoads, J. E. and Fliegelman, M. T.: The Use of 2-methyl-l,4-naphthoouinone (a Synthetic Vitamin K Substitute.)J. A. M. A., 114:400, 1940.
Stewart, J. D. and Rourke, G. M.: Control of Prothrombin Deficiency in Obstructive Jaundice by Use of Vitamin K.J. A. M. A., 113:2223, 1939.
Stewart, J. D.: Prothrombin Deficiency and the Effect of Vitamin K in Obstructive Jaundice and Biliary Fistula.Ann. Surq., 109:588, 1939.
Stewart, J. D., Rourke, G. M. and Allen, A. W.: Control of Post-Operative Bleeding in Obstructive Jaundice.Ann. Surg., 110 : 693, 1939.
Stewart, J. D. and Rourke, G. M.: Prothrombin and Vü amin K Therapy.New England J. Med., 221:403, 1939.
Pohle, F. J. and Stewart, J. K.: Observations on the Plasma Prothrombin and the Effect of Vitamin K in Patients with Liver or Biliary Tract Disease.J. Clin. Invest., 19:365, 1940.
Dam, H. and Glavind, J.: Vitamin K in Human Pathology.Lancet, 1 :720, 1938.
Illingworth, C. F. W.: Hemorrhage in Jaundice.Lancet, 1:1031, 1939.
Engel, R.: Sprue und Vitamin-K-Mangel.Med. Welt., 13:120, 1939.
Mackie, T. T.: Vitamin K Deficiency in the Absence of Jaundice.N. Y. State J. Med., 40 :987, 1940.
Albright, F. and Stewart, J. D.: Hypovitaminosis of All Fat-Soluble Vitamins Due to Steatorrhea. Report of Case.New Eng. J. Med., 223:239, 1940.
Kark, R. and Lozner, E. L.: Nutritional Deficiency of Vitamin K in Man.Lancet, 2:1162, 1939.
Scarborough, H.: Nutritional Deficiency of Vitamin K in Man.Lancet, 1 :1080, 1940.
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Aggeler, P.M., Lucia, S.P. & Fishbon, H.M. Purpura due to vitamin K deficiency in anorexia nervosa. Jour. D. D. 9, 227–229 (1942). https://doi.org/10.1007/BF02997416
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DOI: https://doi.org/10.1007/BF02997416