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A clinical and laboratory study of plasma lipids in obstructive jaundice and several types of hepatic disease

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References

  1. ba]Adler, A. and Lemmel, H.: Zur feineren Diagnostik der Leber- krankbeiten. 1. Cholesterin-Ester im Blutes. Leberkranker.D. Arch. klin. Med., 158:173–214, Jan., 1928.

    CAS  Google Scholar 

  2. Bang, I.: Über Cholesterinämin.Biochem. Ztschr., 91:122–125, Sept., 1918.

    CAS  Google Scholar 

  3. Beumer, H. and Burger, M.: Beiträge zur chemie des Blutes in Krankheiten mit besonderer Berucksichtegung des Lipoids.Ztschr. fur exper. Path. u. Therap., 13:343–361, May, 1913.

    Article  Google Scholar 

  4. Bing, H. J. and Heckscher, A: 11 Mitterlung; Über die Fettmenge des Blutes bei normalen menschen.Biochem. Ztschr., 144:83, 1924.

    Google Scholar 

  5. Blix, G.: Diabetic Lipemia, 1.Acta. Med. Scandinav., 64:142–259, 1926.

    CAS  Google Scholar 

  6. Bloor, W. R.: The Distribution of the Lipoids (“Fats”) in Human Blood.J. Biol. Chem., 25:417, Sept., 1916.

    Google Scholar 

  7. Bloor, W. R.: Determination of Small Amounts of Lipid in Blood Plasma.J. Biol. Chem., 77:53–73, April, 1928.

    CAS  Google Scholar 

  8. Bloor, W. R.: Oxidation Determination of Phospholipid Lecithin and Cephalin) in Blood Tissues.J. Biol. Chem., 82:273–286, May, 1929.

    CAS  Google Scholar 

  9. Boyd, E. M.: A Differential Lipid Analysis in Normal Young Women by Micro-oxidation Methods.J. Biol. Chem., 101:323–336, June, 1933.

    CAS  Google Scholar 

  10. Boyd, E. M.: The Lipopenia of Fever.Canad. M. A. J., 32:500–506, May, 1935.

    CAS  Google Scholar 

  11. Boyd, E. M.: Diurnal Variations in Plasma Lipids.J. Biol. Chem., 110:61–70, June, 1935.

    CAS  Google Scholar 

  12. Boyd, E. M.: Anesthesia and Blood Lipids.S. G. O., 62:377–683, April, 1936.

    Google Scholar 

  13. Boyd, E. M.: The Extraction of Blood Lipids.J. Biol. Chem., 114:223–234, May, 1936.

    CAS  Google Scholar 

  14. Boyd, E. M.: The Oxidative Micro Estimation of Blood Lipids.Am. J. Clin. Path. Tech. Suppl., 2:77–90, May, 1938.

    CAS  Google Scholar 

  15. Boyd, E. M. and Connell, W. F.: Lipopenia Associated with Cholesterol Estersturz in Parenchymatous Hepatic Disease.Arch. Int. Med., 61:755–761, May, 1938.

    CAS  Google Scholar 

  16. Boyd, E. M. and Murray, R. B.: Effects of Anti-coagulants on Blood Lipids.J. Biol. Chem., 117:629–638, 1937.

    CAS  Google Scholar 

  17. Brün, G. C.: Cholesterol Content of the Red Blood Cells in Man.Acta. Med. Scandinav. Supp., 99:3–237, 1939.

    Google Scholar 

  18. Bruger, M. and Habs, H.: Uber Die Veresterung des Serumcholesterins bei Leberkrankheiten.Klin. Wohnschr., 6:2221–2223, Nov. 1927.

    Article  Google Scholar 

  19. Campbell, W. R. and Hanna, M. S.: The Determination of Nitrogen by Modified Kjeldahl Methods.J. Biol. Chem., 119: 107, June, 1937.

    Google Scholar 

  20. Campbell, W. R. and Hanna, M. S.: The Albumins, Globulins and Fibrinogen of Serum and Plasma.J. Biol. Chem., 119:15–33, June, 1937.

    CAS  Google Scholar 

  21. Campbell, W. R. and Hanna, M. S.: Sulfites as Protein and Precipitants.J. Biol. Chem., 119:9–14, June, 1937.

    CAS  Google Scholar 

  22. Chaufford, A., Laroche, G. and Grigaut, A.: De la teneur en Cholesterines des capsules surrènales dans differents ètats Pathologiques.Compt. rend. Soc. de biol., 73:23–25, July, 1912.

    Google Scholar 

  23. Chanutin, A. and Ludewig, S.: The Blood Plasma Cholesterol and Phospholipid Phosphorus in Rats Following Partial Hepatectomy and Following Ligation of the Bile Duct.J. Biol. Chem., 115:1–14, 1936.

    CAS  Google Scholar 

  24. Dennis, W.: Cholesterol in Human Blood Under Pathological Conditions.J. Biol. Chem., 29:93–110, Feb., 1917.

    Google Scholar 

  25. Epstein, E. Z.: Cholesterol of the Blood Plasma in Biliary and Hepatic Disease.Arch. Int. Med., 50:203–222, Aug., 1932.

    CAS  Google Scholar 

  26. Epstein, E. Z. and Greenspan, E. B.: Clinical Significance of Cholesterol Partition of the Blood Plasma in Hepatic and Biliary Diseases.Arch. Int. Med., 58:660, 1936.

    Google Scholar 

  27. Feigel, J.: Untersuchungen Über akute gelbe Leberstrophie. 111— Fette und Lipoids des Blutes.Biochem. Ztschr., 86:1–47, March, 1938.

    Google Scholar 

  28. Feigel, J.: Über das Vorksmen und die Verteilungfi von Fetten und Lipoiden in menschlichen Blutplasma bie Ikterus und Cholemie. Chemische Beitrage sur Kenntnis spezifischer Lipamien. III.Biochem. Ztschr., 90:1–38, Sept., 1918.

    Google Scholar 

  29. Feigel, J.: Ueber das Vorkomnen und die Vertilung von Fetten unde Lipoiden in Menschlichen Blut bei Toxamischen. (hamatinämisehen) Krankeitazustanden. Beobachtungen bei Perneziäsen Anamie und hamalyteschen ihterus) Chemische Beitrage Zur Kenntnis des Lipemiegebietes, VI.Biochem. Ztschr., 93:94–275, 275, 1919.

    Google Scholar 

  30. Folch, Schneider and Van Slyke, D. D.:J. Biol. Chem., 133, (Proc.) xxxiii, May, 1940.

    Google Scholar 

  31. Gardner, J. A. and Fox, F. W.: A Critical Study of the Methods of Estimating Cholesterol and Its Esters in Tissues.Biochem. J., 18:1058–1069, 1924.

    PubMed  CAS  Google Scholar 

  32. Gardner, J. A. and Gainsborough, H.: Cholesterol Secretion in Urine. 1.Biochem. J., 19:667–671, 1925.

    PubMed  CAS  Google Scholar 

  33. Gardner, J. A. and Gainsborough, H.: Studies on the Cholesterol Content of Normal Human Plasma; on the So-Called Alimentary Hyper-cholesterolemia.Biochem. J., 22:1048–1056, 1928.

    PubMed  CAS  Google Scholar 

  34. Gardner, J. A. and Gainsborough, H.: Blood Cholesterol Studies in Biliary and Hepatic Disease.Quart. J. Med., 23:465–483, July, 1930.

    CAS  Google Scholar 

  35. Gardner, J. A. and Williams, M.: A Critical Study of the Methods of Estimating Cholesterol and Allied Substances.Biochem. J., 15:363–375, 1921.

    PubMed  CAS  Google Scholar 

  36. Gildea, E. F., Kohn, E. and Man, E. B.: The Relationship Between Body Build and Serum Lipoids and a Discussion of These Qualities as Pyknophilic and Liptophilic Factors in Structure of Personality.Am. J. Psychist., 92:1247–1250, May, 1936.

    Google Scholar 

  37. Gildea, E. F., Man, E. B. and Biach, R. W.: Long Term Study of the Variations in Serum Proteins, Non Protein Nitrogen and Lipoids in Patients with Schizophrenic and Manic Depressive Psychoses and Normal People.Arch. Neurol. and Psychiat. Cited by Man, Gildea and Peters (92).

  38. Grigaut, A. et. L’Huillier, A.: iaux compare de la cholesterin des hematies et du serum dans le sang normal a pathologique.Compt. rend de Soc. Biol., 73:202–203, July, 1912.

    Google Scholar 

  39. Hawkins, W. B. and Wright. A.: The Blood Plasma Cholesterol; Fluctuations Due to Liver Injury and Bile Duct Obstruction.J. Exper. Med., 59:427–439, April, 1934.

    Article  CAS  Google Scholar 

  40. Jezler, A.: Cholesterinbestimmungen in Blut als Leberfunktions- prüfung.Schweiz. med. Wohnschr., 68:108–110, Jan. 29, 1938.

    CAS  Google Scholar 

  41. Jones, C. A.: A Clinical and Laboratory Study of Plasma Lipids in Obstructive Jaundice and Parenchymatous Hepatic Diseases. Thesis, Graduate School of Medicine, University of Pennsylvania, 1941.

  42. Kelsey, F. E.: Determination of Cholesterol.J. Biol. Chem., 127: 15–22, Jan., 1939.

    CAS  Google Scholar 

  43. Lehnherr, E. R.: The Value of Icteric Indices and Plasma Lipids in the Diagnosis of Jaundice.New England J. Med., 211:487–492, Sept. 14, 1934.

    CAS  Google Scholar 

  44. Luden, G.: Observation on Cholesterin Retention as a Factor in Cell Proliferation.J. Lab. and Clin. Med., 1:662–676, June, 1916.

    CAS  Google Scholar 

  45. Luden, G.: Studies on Cholesterol. 111—The Influence of Bile Derivatives in Bloor’s Cholesterol Determination. (Preliminary Report).J. Biol. Chem., 29:463–476, April. 1917.

    CAS  Google Scholar 

  46. Man, E. B. and Gildea, E. F.: A Modification of the Stoddard and Drury Titrimetric Method for the Determination of the Fatty Acids in Blood Serum.J. Biol. Chem., 99:43–60, Dec., 1932.

    CAS  Google Scholar 

  47. Man, E. B. and Gildea, E. F.: Serum Lipoids in Malnutrition.J. Clin. Invest., 15:203–214, March, 1936.

    Article  PubMed  CAS  Google Scholar 

  48. Man, E. B. and Gildea, E. F.: Variations in Lipemia of Normal Subjects.J. Biol. Chem., 119:769–779, July, 1937.

    CAS  Google Scholar 

  49. Man, E. B. and Peters, J. P.: Gravimetric Determination of Serum Cholesterol Adapted to the Man and Gildea Fatty Acid Method with a Note on the Estimation of Lipoid Phosphorus.J. Biol. Chem., 101:685–695, Aug., 1933.

    CAS  Google Scholar 

  50. Man, E. B. and Peters, J. P.: Serum Lipoids in Diabetes.J. Clin. Invest., 14:579–594. Sept., 1935.

    Article  PubMed  CAS  Google Scholar 

  51. Mancke, R.: Studien Über den Cholesterinstoffweschael 11— Mittelung. Der Cholesteringehalt des Blutserums bei Leberkrankheiten.Deutsches Arch. fur klin. Med., 170:358–368, March, 1931.

    CAS  Google Scholar 

  52. Mjassnikov, A. L.: Uber Die Rolle Der Leber in Cholesterinstoffweschael.Deutsches Klin. Wehnschr., 11:1910–1912, Nov., 1932.

    Google Scholar 

  53. Mueller, J. H.: A Comparison of Results Obtained by Colorimetric and Gravimetric Determination of Cholesterol.J. Biol. Chem., 25:549, 1916.

    CAS  Google Scholar 

  54. Mueller, J. H.: A Note on Solubility of Cholesterol Digitonide.J. Biol. Chem., 30:39–40, May, 1917.

    CAS  Google Scholar 

  55. Mülbock, O. and Kaufman, C.: Die gravimetrische Cholesterin- bestimmung im Blut und Serum.Biochem. Ztschr., 233:222–235, April, 1931.

    Google Scholar 

  56. Mülbock, O. and Kaufman, C.: Die cholesteringsholt im Blut and Serum bei gesunden Frauen in den Verschiedenem Lebeneilten and seiner Baziehangen Zur Sexulfunktion.Ztschr. f. d. Gesam. exper. Med., 102:461–468, Feb., 1938.

    Article  Google Scholar 

  57. Nachlas, A., Duff, G. L., Tidwell, H. C. and Holt, L. E., Jr.: Liver Function as Tested by the Lipemic Curve After Intravenous Fat Administration.J. Clin. Invest., 15:143–151, Jan., 1936.

    Article  PubMed  CAS  Google Scholar 

  58. Okey, R.: Micro Method for Estimation of Cholesterol by Oxidation of Digitonids.J. Biol. Chem., 88:367–379, Aug., 1930.

    CAS  Google Scholar 

  59. Okey, R. and Boyden, R. E.: Studies in Metabolism in Women. III. Variation in the Lipid Content of Blood in Relation to the Menstrual Cycle.J. Biol. Chem., 72:261–281, March, 1927.

    CAS  Google Scholar 

  60. Okey, R. and Stewart, D.: Diet and Blood Cholesterol in Normal Women.J. Biol. Chem., 99:717–727, Feb., 1933.

    CAS  Google Scholar 

  61. Oser, B. L. and Karr, W. G.: The Lipoid Partition in Blood in Health and in Disease.Arch. Int. Med., 37:507–515, Oct., 1925.

    Google Scholar 

  62. Page, S. H., Farr, L. E. and Weech, A. A.: The Effect of Prolonged Low Protein Diet on the Serum Lipoids of Dogs.J. Biol. Chem., 121:111–116, Oct., 1937.

    CAS  Google Scholar 

  63. Page, S. H., Kirk, E., Lewis, W. H., Tompson, W. R. and Van Slyke, D. D.: Plasma Lipids of Normal Men at Different Ages.J. Biol. Chem., 111:613–639, Nov., 1935.

    CAS  Google Scholar 

  64. Peters, J. P. and Eisenman, A. J.: The Serum Proteins in Disease Not Primarily Affecting the Cardiovascular System or Kidneys.Am. J. Med. Sci., 186:808–833., Dec., 1933.

    Article  Google Scholar 

  65. Peters, J. P. and Van Slyke, D. D.: Quantitative Clinical Chemistry. Vol. 1. Interpretations pp. 218–265. William Wilkins & Co., Baltimore, 1931.

    Google Scholar 

  66. Pinkhart, O. C., Bernhard, A. and Kohn, S. L.: The Significance of the Cholesterol Partition of the Blood Serum in Surgery of the Gall Bladder.Am. Surg., 110:701–719, Oct., 1939.

    Google Scholar 

  67. Rakestraw, N. W.: Clinical Factors in Fatigue. 1. The Effect of Muscular Exercise on Certain Common Blood Constituents.J. Biol. Chem., 47:565, Aug., 1921.

    CAS  Google Scholar 

  68. Rakestraw, N. W., Berley, C. V. and Hohn, Y. D.: Chemical Factors in Fatigue; Further Changes in Blood Constituents Following Strenuous Muscular Exercise.J. Biol. Chem., 56: 121–124, May, 1923.

    CAS  Google Scholar 

  69. Reinhold, J. G.: The Determination of Cholesterol. II. Factors Influencing the Accuracy of Various Methods.Am. J. Clin. Path., 6:31–40, Jan., 1936.

    CAS  Google Scholar 

  70. Rothschild, M. A. and Felson, J.: Cholesterol Content of Blood in Various Hepatic Conditions.Arch. Int. Med., 24:520–522, Nov., 1919.

    CAS  Google Scholar 

  71. Salvesen, H. A.: Variations in the Plasma Proteins in Nonrenal Conditions.Acta. Med. Scandinav., 72:113–123, 1929.

    Google Scholar 

  72. Shay, H. and Fieman, P.: The Value of a Combined Study of the Newer Laboratory Tests in the Differential Diagnosis of Toxic and Obstructive Jaundice Including Blood Phosphatase, Cholesterol, Galactose Tolerance and Glucose Tolerance.Am. J. Dig. Dis., 5:597–606, Nov., 1938.

    CAS  Google Scholar 

  73. Smith, R. M. and Marble, A.: The Colorimetric Determination of Free and Combined Cholesterol.J. Biol. Chem., 117:673–684, Feb., 1937.

    CAS  Google Scholar 

  74. Snell, A. M.: The Effects of Chronic Disease of the Liver on the Composition and Physicochemical Properties of Blood, Changes in the Serum Proteins, and Reduction in the Oxygen Saturation of Arterial Blood.Ann. Int. Med., 9:690–711, Dec, 1935.

    Google Scholar 

  75. Sperry, W. M.: The Relationship Between Total and Free Cholesterol in Human Blood Serum.J. Biol. Chem., 114:125–131, May, 1936.

    CAS  Google Scholar 

  76. Sperry, W. M.: The Concentration of Total Cholesterol in the Blood Serum.J. Biol. Chem., 117:391–395, Jan., 1937.

    CAS  Google Scholar 

  77. Sperry, W. M. and Schoenhiemer, R.: Comparison of Serum, Heparinized Plasma, and Oxalated Plasma in Regard to Cholesterol Content.J. Biol. Chem., 110:655–658, Aug., 1935.

    CAS  Google Scholar 

  78. Stepp, W.: Uber des Verhatten des Blutcholestrins beim Ikterus.Baitr. Pathol. Anst. U. Z. allg. Pathol., 69:233–241, 1921.

    Google Scholar 

  79. Stepp, W.: Uber den Cholesteringehalt des Blutserums bei Krankhiesten.Münch. med. Wohnschr., 65:781–783, July, 1931.

    Google Scholar 

  80. Stern, R. and Suchantke, G.: Clinical Significance of Cholesterol in Bile and Blood Serum; Equilibrium of Cholesterol and Cholesterol Ester in Disturbed Liver Function.Arch. f. exper. Path. and Pharmakol., 115:221–231, 1926.

    Article  CAS  Google Scholar 

  81. Stroebe, F.: Cholesterinëmie bei Lebercirrhose und hepatacel- luläron Ikterus.Klin. Wohnschr., 11:636–639, April, 1932.

    Article  CAS  Google Scholar 

  82. Stoesser, A. V.: Study of Cholesterol Fractions in Acute Infection of Infants with and Without Eczema.Proc. Soc. Exper. Biol. and Med., 34:10–11, Feb., 1936.

    CAS  Google Scholar 

  83. Thannhauser, S. J. and Schaber, H.: Ueber die Beziehungen des gleichgewichtes cholesterin und cholesterinester in Blut und Serum zur Leberfunction.Lin. Wohnschr., 5:252–253, Feb., 1926.

    CAS  Google Scholar 

  84. Tumen, H. and Bockus, H. L.: Clinical Significance of Serum Proteins in Hepatic Disease Compared with Other Liver Function Tests.Am. J. Med. Sci., 193:788-800.

  85. Turner, K. B. and Stiener, A.: A Long Term Study of the Variations of Serum Cholesterol in Man.J. Clin. Invest., 18: 45–49, Jan., 1939.

    Article  PubMed  CAS  Google Scholar 

  86. Weir, J. F.: The Diagnosis of Jaundice, Value of Clinical and Laboratory Data.Am. J. Surg., 15:494–503, March, 1932.

    Article  Google Scholar 

  87. Wendt, H.: Uber das Verhalten der Cholesterinester in Blutzerum Leberkranker.Klin. Wohnschr., 8:1215–1218, June, 1929.

    Article  CAS  Google Scholar 

  88. Weston, P. G.: Colorimetric Methods for Determining Serum Cholesterol.J. Biol. Chem., 28:383–387, Jan., 1917.

    CAS  Google Scholar 

  89. Whipple, G. H.: Protein Production and Exchange in the Body Including Hemoglobin, Plasma Protein and Cell Protein, 196:609–621, Nov., 1938.

    CAS  Google Scholar 

  90. White, F. W., Deutsche, E. and Maddock, S.: The Comparative Value of Serial Hippuric Acid Excretion, Total Cholesterol, Cholesterol Ester and Phospholipid Tests in Diseases of the Liver. 1. The Results of the Tests.Am. J. Dig. Dis., 5:603, Nov., 1939.

    Google Scholar 

  91. Yasizumi, Z.: Clinical Significance of Plasma Lipoid Content and Cholesterol Ester.Tokyo J. Exper. Med., 33:165–180, May, 1938.

    Article  Google Scholar 

  92. Yasuda, M.: On Lieberman-Burchard Reaction of Bound Cholesterol.J. Biochem, (Japan), 24:443–445, Nov., 1936.

    CAS  Google Scholar 

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From the Medical and Gastro-Enterological Services of the Graduate Hospital of the University of Pennsylvania

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Jones, C.A. A clinical and laboratory study of plasma lipids in obstructive jaundice and several types of hepatic disease. Jour. D. D. 9, 001–013 (1942). https://doi.org/10.1007/BF02996987

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