Skip to main content
Log in

Liver function tests in the aged (The serum cholesterol partition, bromsulphalein, cephalin-flocculation and oral and intravenous hippuric acid tests)

  • Published:
The American Journal of Digestive Diseases

Summary

  1. 1.

    Various liver function tests were performed on normal individuals past sixty years of age.

  2. 2.

    In eighty-six per cent of these subjects, at least one of the tests showed evidence of liver dysfunction.

  3. 3.

    Abnormal results of liver function tests may be encountered in apparently healthy subjects above sixty years of age.

The authors express their appreciation to Dr. Samuel Seidenberg for his cooperation in this study.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Rafsky. H. A. and Newman, B.: Cholesterol Partition in the Aged.J. Lab. and Clin. Med., 27:1563, 1942.

    CAS  Google Scholar 

  2. Hanser, F. M.: The Flocculation of Cephalin-Cholesterol Emulsions by Pathological Sera.Tr. A. Am. Physicians, 53:148, 1938.

    Google Scholar 

  3. Rosenthal, S. M. and White, E. C.: Clinical Application of the Bromsulphthalein Test for Hepatic Function.J. A. M. A., 84:1112, April 11, 1925.

    Google Scholar 

  4. Quick, A. J.: The Synthesis of Hippuric Acid. A New Test of Liver Function.Am. J. Med. Sci., 185:630. 1933.

    Article  Google Scholar 

  5. Quick, A. J.: Intravenous Modification of the Hippuric Acid Test for Liver Function.Am. J. Dig. Dis., 6:716, 1939.

    CAS  Google Scholar 

  6. Mateer, J. G. : Personal communication.

  7. Bloor, W. R. and Knudson, A. J.: Cholesterol and Cholesterol Esters in Human Blood.J. Biol. Chem., 27:107, 1916.

    CAS  Google Scholar 

  8. Todd, J. C. and Sanford, A. H.: Clinical Diagnosis by Laboratory Methods. Saunders, Philadelphia, p. 365, 1939.

    Google Scholar 

  9. Cantarow, A. and Tromper, M.: Clinical Biochemistry. Saunders, Philadelphia, p. 172, 1939.

    Google Scholar 

  10. Bodansky, M. and Bodansky, O.: Biochemistry of Disease. Mac-millan, New York, p. 145. 1940.

    Google Scholar 

  11. Stitt, E. R., Clough, P. W. and Clough. M. C.: Practical Bacteriology, Hematology, and Animal Parasitology. Blakiston, Philadelphia, p. 677, 1938. 12. Ibid., p. 766.

    Google Scholar 

  12. Weichselbaum, T. E. and Probstein, J. G.: Determination of Hippuric Acid in Urine.J. Lab. ami Clin. Med., 24:636, 1939.

    CAS  Google Scholar 

  13. Mateer, J. G., Baltz, J. I., Marion, D. F. and Hollands, R. A.: A Comparison of the Newer Liver Function Tests. (Comparison of the Intravenous Hippuric Acid Test, the Cephalin Flocculation Test, the Colloidal Gold Test and a Serial Bromsulphthalein Test with the Oral Hippuric Acid Test and the Rosen-thai Bromsulphthalein Test).Am. J. Dig. Dis., 9:13, 1942.

    CAS  Google Scholar 

  14. Pohle, F. J. and Stewart, J. K.: The Cephalin-Cholesterol Flocculation Test as an Aid in the Diagnosis of Liver Disorders.J. Clin. Invest., 20:241, 1941.

    Article  PubMed  CAS  Google Scholar 

  15. Snell, A. M. and Magath, T. B.: The Use and Interpretation of Tests for Liver Function.J. A. M. A., 110:167, Jan. 15, 1938.

    CAS  Google Scholar 

  16. Soffer, L. J.: Present Day Status of Liver Function Tests.Medicine, 14:185, 1935.

    Article  Google Scholar 

  17. Paulson, M. and Wyler, C. I.: Multiple Tests of Hepatic Function in Gastroenteric Malignancy. The Value of the Bromsulphthalein, Hippuric Acid and the van den Bergh Reaction in Detecting Hepatic Metastasis, with an Evaluation of the Normality of the Hippuric Acid Test.Ann. Int. Med., 16:872, 1942.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rafsky, H.A., Newman, B. Liver function tests in the aged (The serum cholesterol partition, bromsulphalein, cephalin-flocculation and oral and intravenous hippuric acid tests). Jour. D. D. 10, 66–69 (1943). https://doi.org/10.1007/BF02996916

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02996916

Keywords

Navigation