Abstract
Malignant Schwannoma of the sinonasal tract is an extremely rare tumour. So far, only 19 cases have been reported in the literature. We report herein a case of malignant schwannoma involving nasal cavity, maxillary antrum and ethmoid sinus in a 60-year-old male patient. The patient was treated with surgery and post-operative radiotherapy. He currently remains free of the disease 15 months after the diagnosis and twelve months after completing therapy.
References
Ducatman, B.S., Scheithauer, B. W., Piepgras, D. G., et al. (1986): Malignant peripheral nerve sheath tumours. A clinicopathologic study of 20 cases. Cancer 57: 2006–2021.
Erlandson, R.A., Wooodrujj, J.M. (1982) Peripheral nerve sheath tumours: an electron microscopy study of 43 cases. Cancer 49: 273–287.
Ghosh, B.C., Ghosh, L., Huvos, A. G., et al (1973): Malignant Schwannoma a clinicopathologic study. Cancer 31: 184–190.
Harkin, J.C., Reed, R.J. (eds) (1969): Tumours of the peripheral nervous system. Atlas of tumour pathology. Series 2, Fascicle 3. Washington, DC: AFIP.
Hellquist, H.B., Lundgren, J. (1991): Neurogenic sarcoma of the sinonasal tract. The Journal of Laryngology and Otology 105: 186–190.
Kameyama, Y., Maeda, H., Nakane, S., et al (1987): Malignant Schwannoma of the maxilla in a patient without neurofibromatosis. Histopathology 11: 1205–1210.
Leslie, M.D., Cheung, K.Y.P. (1987): Malignant transformation of neurofibromas at multiple sites in a case of neurofibromatosis. Postgraduate Medical Journal 63: 131–133.
Maroun, F.B., Sadler, M., Murray, G.P., et al (1986): Primary malignant tumours of the trigeminal nerve. Canadian Journal of Neurological Sciences 13: 146–148.
Millard and Busser (1952): Schwannome du maxillaire superieur ďevolution maligne. Ann Otolaryngol Chir Cervicofac. 69: 706–708.
Nagayama, I., Nishimura, T., Furukawa, M. (1993): Malignant Schwannoma arising in a paranasal sinus. The Journal of Laryngology and Otology 107(2): 146–148.
Perzin, K.H., Panyu, H., Wechter, S. (1982): Nonepithelial tumours of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. XII: Schwann cell tumours (Neurilemoma, neurofibroma, maligant schwannnoma). Cancer 50: 2193–2202.
Pizzo, P.A., Horowitz, M.E., Poplack, D. G., et al (1993): Solid tumours of childhood, in Devitta Jr VT, Hellman S, Rosenberg SA, (eds): Cancer principles & practice of oncology. (ed 4). Philadelphia, Lippincott, 1993, pp 1738–1791.
Robitaille, Y., Seemayer, T.A., Deiry, A.E. (1975): Peripheral nerve sheath tumours involving paranasal sinuses: A case reportg and review of the literature. Cancer 35: 1254–1258.
Tanwar, R.K., Kumar, R., Malik, S., et al (1995): Orbital neurofibrosarcoma: A case Report. Indian Journal of Pathology and Microbiology 38: 91–94.
Vege, D. S., Chinoy, R.L., Ganesh, B., et al (1994): Malignant Peripheral Nerve Sheath Tumours of the Head and Neck: A clinicopathological study. Journal of Surgical oncology 55: 100–103.
Wick, M. R., Swanson, P.E. Scheithauer, B.W., et al (1987): Malignant peripheral nerve sheath tumour. An immunohistochemical study of 62 cases. American Journal of clinical pathology 87: 425–433.
Woodruff, J.M., Horten, B.C., Erlandson, R.A. (1990): Pathology of peripheral nerves and paragangliomas. In siverberg SS (ed): Principles and practice of surgical pathology. New York, Churchill Livingstone. pp 1997–2017.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Maheshwari, G.K., Baboo, H.A., Gopal, U. et al. Malignant schwannoma of the sinonasal tract. IJO & HNS 51, 47–50 (1999). https://doi.org/10.1007/BF02996845
Issue Date:
DOI: https://doi.org/10.1007/BF02996845