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A clinical trial of cotrimazine (Aubril) in Ear, Nose & Throat infections

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Abstract

An open clinical trial of cotrimazine (Aubril) was conducted in 44 patients suffering from Ear, Nose and Throat (EIMT) infections. The daily dosage employed was 1 g. for 7 to 10 days with a loading dose of 2 g. on the first day. A total of 52 infections were present in the 38 patients finally assemble for efficacy and tolerability. Thiry-five infections were considered cured, 16 improved, while only 1 failed to respond, Side effects were recorded in 3 patients (7.9%) and consisted of nausea in two patients and pain in abdomen in the third. We conclude that cotrimazine (Aubril) is an efficacious and well tolerated antimicrobial agent for the treatment of common EIMT infections.

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Authors and Affiliations

  1. Maulana Azad Medical College & Assoc. LNJPN & GB Pant Hospitals, 110 002, New Delhi

    P. K. Kakar (Prof. & Head of ENT Department), P. L. Dhingra (Professor of ENT), A. K. Agarwal (Assistant Professor of ENT), A. M. Shenoy (Senior Resident of ENT) & J. Kaur (Postgraduate Student in ENT)

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  1. P. K. Kakar
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  2. P. L. Dhingra
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  3. A. K. Agarwal
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  4. A. M. Shenoy
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  5. J. Kaur
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Kakar, P.K., Dhingra, P.L., Agarwal, A.K. et al. A clinical trial of cotrimazine (Aubril) in Ear, Nose & Throat infections. Indian J Otolaryngol 39, 92–94 (1987). https://doi.org/10.1007/BF02995366

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  • DOI: https://doi.org/10.1007/BF02995366

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