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A case of general paresis showing marked treatment-associated improvement of cerebellar blood flow by quantitative imaging analysis

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Abstract

We describe a patient with general paresis who developed progressive dementia and a cerebellar syndrome including wide-based gait, slurred speech, and intention tremor. Quantitative analysis by means of a Patlak plot of single-photon emission computed tomography (SPECT) with99mTc-ethyl cysteinate dimer showed generally low blood flow in the cerebrum and the cerebellum. After antisyphilitic therapy, blood flow in the brain, especially in the cerebellum, improved noticeably, as did the cognitive disorder and the cerebellar syndrome.

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Authors and Affiliations

  1. Department of Psychiatry, Nara Medical University, Shijo-cho 840, 634-8522, Kashihara, Japan

    Masayuki Morikawa, Jun Kosaka, Hiroyoshi Ohsawa, Junzo Iida & Toshifumi Kishimoto

  2. Department of Oncoradiology, Nara Medical University, Shijo-cho 840, 634-8522, Kashihara, Japan

    Teruhiko Imai

Authors
  1. Masayuki Morikawa
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  2. Jun Kosaka
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  3. Teruhiko Imai
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  4. Hiroyoshi Ohsawa
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  5. Junzo Iida
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  6. Toshifumi Kishimoto
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Corresponding author

Correspondence to Masayuki Morikawa.

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Morikawa, M., Kosaka, J., Imai, T. et al. A case of general paresis showing marked treatment-associated improvement of cerebellar blood flow by quantitative imaging analysis. Ann Nucl Med 16, 71–74 (2002). https://doi.org/10.1007/BF02995296

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  • DOI: https://doi.org/10.1007/BF02995296

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