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Two plant alkaloids isolated fromCorydalis longipes as potential antifungal agents

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Abstract

The alkaloidsN-methylhydrasteine hydroxylactam and 1-methoxyberberine chloride were isolated fromCorydalis longipes. Both alkaloids showed high efficacy individually (in concentration of 50–150 ppm) and also in a 1 : 1 mixture against spore germination of some fungi,viz. Alternaria alternata, A. brassicae, Curvularia maculans, Curvularia sp.,Colletotrichum gloeosporioides, Colletotrichum sp.,Helminthosporium speciferum, H. pennisetti, Helminthosporium sp. andUstilago cynodontis. The antifungal effect of single compounds was dose-dependent. If the mutual ratio of the two components in the mixture was changed from 1 : 1 to a major content of any of the two compounds, the inhibitory effect on spore germination decreased.

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Authors and Affiliations

  1. Department of Mycology and Plant Pathology, Institute of Agricultural Sciences, Banaras Hindu University, 221 005, Varanasi, India

    N. V. Singh, S. Azmi, S. Maurya & U. P. Singh

  2. Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, 221 005, Varanasi, India

    R. N. Jha & V. B. Pandey

Authors
  1. N. V. Singh
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  2. S. Azmi
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  3. S. Maurya
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  4. U. P. Singh
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  5. R. N. Jha
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  6. V. B. Pandey
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Correspondence to U. P. Singh.

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Singh, N.V., Azmi, S., Maurya, S. et al. Two plant alkaloids isolated fromCorydalis longipes as potential antifungal agents. Folia Microbiol 48, 605–609 (2003). https://doi.org/10.1007/BF02993466

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  • DOI: https://doi.org/10.1007/BF02993466

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