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Human serum sickness

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References

  1. von Pirquet CE: Allergy. Arch Intern Med 7:259–426, 1911

    Google Scholar 

  2. Cochrane CG, Koffler D: Immune complex disease in experimental animals and man. Adv Immunol 16:185–263, 1973

    Article  PubMed  CAS  Google Scholar 

  3. Frick OL: Serum sickness. In Middleton E, Reed CE, Ellis EF (eds): Allergy: principles and practice. St. Louis, CV Mosby, 1978, pp 574–583

    Google Scholar 

  4. Fauci AS: Vasculitis. In Parker CW (ed): Clinical immunology. Philadelphia, Saunders, 1980, pp 486–490

    Google Scholar 

  5. Mackenzie GM, Hanger FM: Serum disease and serum accidents. JAMA 94:260–265, 1930

    Google Scholar 

  6. von Pirquet CE, Schick B: Die Serum Krankheit (serum sickness). Baltimore, Williams & Wilkins, 1951

    Google Scholar 

  7. Karliner JS, Belaval GS: Incidence of reactions following administration of antirabies serum. JAMA 193:109, 1965

    Google Scholar 

  8. Report of the International Conference of Adverse Reactions Reporting Systems. National Academy of Sciences, Washington D.C., 1971

  9. Mannick M: Characteristics of immune complexes and principles of immune complex diseases. In McCarty DV (ed): Arthritis and allied conditions. Philadelphia, Lea & Febinger, 1979, pp 256–266

    Google Scholar 

  10. Barnett EV, Knutson DW, Abrass CK, Chia DS, Young LS, Liebling MR: Circulating immune complexes: Their immunochemistry, detection, and importance. Ann Intern Med 91:430–440, 1979

    Google Scholar 

  11. Stiehm RE, Rachelefsky GS: Control of antibody synthesis. In Middleton E, Reed CE, Ellis EF (eds): Allergy: principles and practice. St. Louis, CV Mosby, 1978, pp 37–51

    Google Scholar 

  12. Isaacs KL, Miller F: Role of antigen size and change in immune complex GN. Lab Invest 47:198–205, 1982

    PubMed  CAS  Google Scholar 

  13. McLeish KR, Gohara AF, Gunning WT: Chronic serum sickness in the mouse. Nephron 31:28–83, 1982

    Article  Google Scholar 

  14. Iverson BM, Matre R, Ofstad J: The heterologous immune complex GN. Acta Pathol Microbiol Immunol Scand 90:241–256, 1982

    Google Scholar 

  15. Weaver GH: Serum disease. Arch Intern Med 3:485, 1909

    Google Scholar 

  16. Kohler P: Immune complexes and allergic disease. In Middleton E, Reed CE, Ellis E (eds): Allergy: principles and practice. St. Louis, CV Mosby, 1978, pp 155–176

    Google Scholar 

  17. Wells JV: Immune mechanisms in tissue damage. In Fudenberg HH, Stites DP, Caldwell JE, Wells JV (eds): Basic and clinical immunology. Los Altos, Lange Medical Publications, 1980, pp 191–206

    Google Scholar 

  18. Theofilopoulos AN, Dixon FJ: The biology and detection of immune complexes. Adv Immunol 28:89–220, 1980

    Article  Google Scholar 

  19. Devey ME, Bleasdale K, Collins M, Steward MW: Experimental antigen-antibody complex disease in mice. Int Arch Allergy Appl Immunol 68:47–53, 1982

    PubMed  CAS  Google Scholar 

  20. Cochrane CG, Dixon FJ: Immune complex injury. In Samter M (ed): Immunological diseases. Boston, Little, Brown, 1978, pp 210–229

    Google Scholar 

  21. Reinhardt MC, Devey M, Collins M, Gregory B, Steward MW: The effect of protein deficiency on the development of chronic antigen antibody complex disease in mice. Clin Exp Immunol 44:528–557, 1981

    PubMed  CAS  Google Scholar 

  22. Arbesman CE, Kantor SZ, Rose NR, Witebsky E: Serum sickness. J Allergy 31:257–272, 1960

    Article  PubMed  CAS  Google Scholar 

  23. Mannik M: Pathophysiology of circulating immune complexes. Arthritis Rheum 25:783–787, 1982

    Article  PubMed  CAS  Google Scholar 

  24. Mannik M, Arend WP: Fate of preformed immune complexes in rabbits and rhesus monkeys. J Exp Med 134:195–315, 1971

    Google Scholar 

  25. Haakenstad AO, Mannik M: Saturation of the reticuloendothelial system with soluble immune complexes. J Immunol 112:1934–1948, 1974

    Google Scholar 

  26. Cochrane CG: Mechanisms involved in the deposition of immune complexes in tissues. J Exp Med 134:753–893, 1971

    Article  Google Scholar 

  27. Wiggins RC, Cochrane CG: Immune complex mediated biologic effects. N Engl J Med 304:518–520, 1981

    PubMed  CAS  Google Scholar 

  28. Gelfand MC, Frank MM, Green I: A receptor for the 3rd component of complement in the human renal glomerulus. J Exp Med 142:1029–1034, 1975

    Article  PubMed  CAS  Google Scholar 

  29. Lamers MC: Factors influencing the development of immune complex diseases. Allergy 36:527–535, 1982

    Article  Google Scholar 

  30. Inman RD, Day NK: Immunologic and clinical aspects of immune complex disease. Am J Med 70:1097, 1981

    Article  PubMed  CAS  Google Scholar 

  31. Weisman G, Smolen JE, Korchak HM: Release of inflammatory mediators from stimulated neutrophils. N Engl J Med 303:27–34, 1980

    Google Scholar 

  32. Henson PM: Interaction of cells with immune complexes: Adherence, release of corticosteroids, and tissue injury. J Exp Med 134:1145–1355, 1981

    Google Scholar 

  33. Albini B, Ossi E, Andres G: The pathogenesis of pericardial, pleural, and peritoneal effusions in rabbits with serum sickness. Lab Invest 37:64–78, 1977

    PubMed  CAS  Google Scholar 

  34. Fish AJ, Michael AF, Vernier RL, Good RA: Acute serum sickness nephritis in the rabbit. Am J Pathol 49:997–1013, 1966

    PubMed  CAS  Google Scholar 

  35. Wilson CB, Dixon FJ: Quantitation of acute and chronic serum sickness in the rabbit. J Exp Med 134:75–185, 1971

    Article  Google Scholar 

  36. Holdsworth SR, Neale TJ, Wilson CB: The participation of macrophages and monocytes in experimental immune complex GN. Clin Immunol Immunopathol 15:510–524, 1980

    Article  PubMed  CAS  Google Scholar 

  37. Hunsicker LG, Shearer TP, Plattner SB, Weisenburger D: The role of monocyte in serum sickness nephritis. J Exp Med 150:413–425, 1979

    Article  PubMed  CAS  Google Scholar 

  38. Levine BB: Immunologic mechanisms of penicillin allergy. A haptenic model for the study of allergic diseases in man. N Engl J Med 275:1115–1125, 1966

    PubMed  CAS  Google Scholar 

  39. Parker CW: Drug allergy. N Engl J Med 292:511–514, 1975

    PubMed  CAS  Google Scholar 

  40. Hoornrje SJ, et al: Serum sickness-like syndrome with membranous glomerulopathy in patient on captopril (letter). Lancet 2:1297, 1979

    Article  Google Scholar 

  41. Sanders WE, et al: Adverse reactions to cephalothin and cephapirin. N Engl J Med 290:424–429, 1974

    PubMed  CAS  Google Scholar 

  42. Wolfe MS, Moede AL: Serum sickness with furazolidone. Am J Trop Med Hygiene 27:762–765, 1978

    CAS  Google Scholar 

  43. Prazak G: Tinea pedis—griseofulvin. Arch Dermatol 81:825, 1960

    Google Scholar 

  44. Williams BD, et al: Circulating immune complexes after repeated halothane anesthesia. Br Med J 2:159–162, 1977

    Article  PubMed  CAS  Google Scholar 

  45. Smith JM, Springett VH: Serum transminase levels during treatment with isoniazid, streptomycin, and PAS. Tubercle 47:245, 1966

    Article  PubMed  CAS  Google Scholar 

  46. Bernstein SH, Houser HB: Sensitivity reactions to intramuscular injection of benzathine penicillin. N Engl J Med 260:747–751, 1959

    PubMed  CAS  Google Scholar 

  47. Cormia FE, et al: Reactions to penicillin. Bull US Army Med Dept 4:694–702, 1945

    Google Scholar 

  48. Fellner MJ, et al: Double reaction to penicillin: Anaphylactic and serum sickness-like reactions due to a single dose. Arch Dermatol 96:687–688, 1967

    Article  PubMed  CAS  Google Scholar 

  49. Zidar BL, et al: Diphenylhydantoin induced serum sickness with fibrin platelet thrombi in lymph node micro vasculature. Am J Med 58:704–708, 1975

    Article  PubMed  CAS  Google Scholar 

  50. Braverman IM, Levin J: Dilantin-induced serum sickness; case report and inquiry into its mechanism. Am J Med 35:418–422, 1963

    Article  PubMed  CAS  Google Scholar 

  51. Haruda F: Phenytoin hypersensitivity; 38 cases. Neurology 29:1480–1485, 1979

    PubMed  CAS  Google Scholar 

  52. Longcope WT: Serum sickness and analogous reactions from certain drugs particularly the sulfonamides. Medicine 22:251–286, 1943

    Article  CAS  Google Scholar 

  53. Rich AR: The role of hypersensitivity in periarteritis nodosa as indicated by seven cases developing during serum sickness and sulfonamide therapy. Bull Johns Hopkins Hosp 71:123–139, 1942

    Google Scholar 

  54. Rytand DA: Onset of the nephrotic syndrome during a reaction to bee sting. Stanford Med Bull 13:224–233, 1955

    PubMed  CAS  Google Scholar 

  55. Sheehan RK: Serum sickness and recurrent angioedema after bee sting. JAMA 193:155–156, 1965

    PubMed  CAS  Google Scholar 

  56. Jex-Blake AJ: Bee stings. E Afr Med J 19:74, 1942

    Google Scholar 

  57. Kohler PF: Asthma hyposensitization and arteritis: Direct relationship or red herring? J Allergy Clin Immunol 57:232, 1976 (abstr)

    Google Scholar 

  58. Phanupak P, Kohler PF: Recent advances in allergic vasculitis. Adv Allergy Pulmon Dis 5:19, 1978

    Google Scholar 

  59. Daschbach RJ: Serum sickness and tetanus immunization (letter). JAMA 220:1619, 1972

    Article  PubMed  CAS  Google Scholar 

  60. Dietz GF: Serum sickness after tetanus toxoid injection (letter). JAMA 220:137, 1972

    Google Scholar 

  61. Bayer AS, et al: Circulating immune complexes in infective endocarditis. N Engl J Med 295:1500–1505, 1976

    PubMed  CAS  Google Scholar 

  62. Kohler PF: Clinical immune complex disease; manifestations in systemic lupus erythematosus and hepatitis B virus infection. Medicine 52:419–429, 1973

    Article  PubMed  CAS  Google Scholar 

  63. London WT: Hepatitis B virus and antigen-antibody complex diseases (editorial). N Engl J Med 296:1528–1529, 1977

    PubMed  CAS  Google Scholar 

  64. Kojis FG: Serum sickness and anaphylaxis; analysis of cases of 6,211 patients treated with horse serum for various infections. Am J Dis Child 64:93–143, 1942

    Google Scholar 

  65. Vessal S, Kravis LP: Immunologic mechanisms responsible for adverse reactions to routine immunizations in children. Clin Pediatr 15:688–696, 1976

    Article  CAS  Google Scholar 

  66. Arbesman CE, et al: Immunologic studies of a Guillian-Barré syndrome following tetanus antitoxin. NY State J Med 58:2647, 1958

    CAS  Google Scholar 

  67. De La Pava S, et al: Fatal glomerulonephritis after receiving horse anti-human-cancer serum. Arch Intern Med 109:67–75, 1962

    Google Scholar 

  68. Barnett EV, et al: Serum sickness and plasmacytosis: A clinical, immunologic, and hematologic analysis. Am J Med 35:113–122, 1963

    Article  PubMed  CAS  Google Scholar 

  69. Vaughan JH, et al: Serum sickness: Evidence in man of antigen-antibody complexes and free light chains in the circulation during the acute reaction. Ann Intern Med 67:596–602, 1967

    PubMed  CAS  Google Scholar 

  70. De Carpio J, et al: Transient monoclonal proteins in drug hypersensitivity reactions. Am J Med 66:1051–1056, 1979

    Article  PubMed  Google Scholar 

  71. Dixon FJ: The role of antigen-antibody complexes in disease. Harvey Lect 58:21, 1963

    PubMed  CAS  Google Scholar 

  72. Lieberman P, et al: Studies of urticaria and acute serum sickness with the C1q precipitin test. Arch Intern Med 137:440–442, 1977

    Article  PubMed  CAS  Google Scholar 

  73. Hardin JA, et al: Immune complexes and the evolution of lyme arthritis; dissemination and localization of C1q binding activity. N Engl J Med 301:1358–1363, 1979

    Article  PubMed  CAS  Google Scholar 

  74. Lambert PH, et al: A WHO collaborative study for the evaluation of eighteen methods for the detection of immune complexes in serum. J Clin Lab Immunol 1:1–15, 1978

    Google Scholar 

  75. Reisman RE, et al: Serum sickness. II. Demonstration and characterization of antibodies. J Allergy 32:531, 1961

    Article  PubMed  CAS  Google Scholar 

  76. Kniker WT, et al: Prevention of immune complex disease (serum sickness) by antagonists of vasoactive amines. Pediatr Res 5:381, 1971 (abstr)

    Google Scholar 

  77. Patterson R: Allergic diseases. Diagnosis and management. Philadelphia, J.P. Lippincott, 1980

    Google Scholar 

  78. Gellis SS, et al: Current pediatric therapy. Philadelphia, Saunders, 1966

    Google Scholar 

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Naguwa, S.M., Nelson, B.L. Human serum sickness. Clin Rev Allergy 3, 117–126 (1985). https://doi.org/10.1007/BF02993045

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