Abstract
An X-ray microprobe for trace elemental analysis at micrometer spatial resolutions, using synchrotron radiation (SR), is under development. The facility consists of two beamlines, one including a 1∶1 focusing mirror and the other an 8∶1 ellipsoidal mirror. At present, “white light” is used for excitation of the characteristic X-ray fluorescence lines. Sensitivities in thin biological samples are in the range of 2–20 fg in 100 μm2 areas in 5 min irradiation times. Scanning techniques, as well as microtomography and chemical speciation, are discussed. Application to a specific biomedical study is included.
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Gordon, B.M., Jones, K.W., Hanson, A.L. et al. An X-ray microprobe facility using synchrotron radiation. Biol Trace Elem Res 26, 133–141 (1990). https://doi.org/10.1007/BF02992666
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DOI: https://doi.org/10.1007/BF02992666