Abstract
Progression or reactivation of Otosclerotic disease as shown by tomography, despitemoderate dosage Sodium Fluoride therapy, is due to poor intestinal absorption of the drug in its enteric coated form. It is also seen when the drug is often temporarily withdrawn. During Sodium Fluoride therapy for Otosclerosis an intestinal absorption test of the preparation is necessary.
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References
Deka, R.C., Kacker S.K., Shambaugh G.E., Jr. (1978): Intestinal absorption of Fluoride-Laryngoscope 88: 1918–1921.
Shambaugh G.E. Jr. & Petrovic, A., (1968): Effects of Sodium Flouride on bone:An application to Otosclerosis and other declacifying bone diseases.Journal of the American Medical Association.204: 967.
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Deka, R.C. Progression or reactivation of Otosclerotic lesion despite Fluoride therapy. Indian J Otolaryngol 31, 101–102 (1979). https://doi.org/10.1007/BF02992405
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DOI: https://doi.org/10.1007/BF02992405