Summary
A method by which the standard deviation of the expectednumber of recessives may be calculated for human or other data derived from small families is given. This involves the same functions as previously tabulated for a method of comparing the hypothetical expectation of recessives with an“adjusted” proportion based on the observed data. It leads to precisely the same numerical results and is free from ana priori assumption implicit in the earlier statement.
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References
Eisher, R. A. (1921). “On the mathematical foundations of theoretical statistics.”Phil. Trans. Roy. Soc. A,222, 309.
Haldane, J. B. S. (1932). “A method for investigating recessive characters in Man.”Journ. Gen. 25.
Hogben, L. T. (1931). “The genetic analysis of familial traits. 1. Single gene substitutions.”Journ. Gen. 25.
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Hogben, L. The factorial analysis of small families with parents of undetermined genotype. Journ. of Genetics 26, 75–79 (1932). https://doi.org/10.1007/BF02991444
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DOI: https://doi.org/10.1007/BF02991444