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Adrenal corticosteroids in the treatment of asthma

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References

  1. Hench PS, Kendall EC, Slocumb CH, Polley HF: The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone, compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis. Proc Staff Meet Mayo Clinic 24:181–197, 1949

    CAS  Google Scholar 

  2. Dluhy RG, Lauler DP, Thom GW: Pharmacology and chemistry of adrenal glucocorticoids. Med Clin North Am 57:1155–1165, 1973

    PubMed  CAS  Google Scholar 

  3. Baxter JD, Funder JW: Hormone receptors. N Engl J Med 301:1149–1161, 1979

    PubMed  CAS  Google Scholar 

  4. Morris HG: Factors that influence clinical responses to administered corticosteroids. J Allergy Clin Immunol 66:343–346, 1980

    Article  PubMed  CAS  Google Scholar 

  5. Zurier RB, Weissman G: Anti-immunologic and anti-inflammatory effects of steroid therapy. Med Clin N Am 57:1295–1307, 1973

    PubMed  CAS  Google Scholar 

  6. Fauci AS: Immunosuppressive and anti-inflammatory effects of glucocorticoids, in Baxter JD, Rousseau GG (eds): Glucocorticoid Hormone Action. New York, Springer-Verlag, 1979, pp 449–465

    Google Scholar 

  7. Slott RI, Zweiman B: Histologic studies of human skin test responses to ragweed and compound 48/80. II. Effects of corticosteroid therapy. J Allergy Clin Immunol 55:232–240, 1975

    Article  PubMed  CAS  Google Scholar 

  8. Ellul-Micallef R, Fenech FF: Effect of intravenous prednisolone in asthmatics with diminished adrenergic responsiveness. Lancet 2:1269–1271, 1975

    Article  PubMed  CAS  Google Scholar 

  9. Stephan WC, Chick TW, Avner BP, Jenne JW: Tachyphylaxis to inhaled isoproterenol and the effect of methylprednisolone in dogs. J Allergy Clin Immunol 65:105–109, 1980

    Article  PubMed  CAS  Google Scholar 

  10. Davies AO, Lefkowitz RJ: Agonist-promoted high affinity state of the β-adrenergic receptor in human neutrophils: Modulation by corticosteroids. J Clin Endocrinol Metab 53:703–708, 1981

    PubMed  CAS  Google Scholar 

  11. Kirkpatrick CH: Steroid therapy of allergic diseases. Med Clin N Am 57:1309–1320, 1973

    PubMed  CAS  Google Scholar 

  12. Claman HN: How corticosteroids work. J Allergy Clin Immunol 55:145–151, 1975

    Article  PubMed  CAS  Google Scholar 

  13. Jansani MK: Possible modes of action of ACTH and glucocorticoids in allergic diseases. Clin Allergy 2:1–41, 1972

    Article  Google Scholar 

  14. DeVries K, Orie NGM: Corticosteroids and allergy. Scand J Respir Dis Suppl 68:24–30, 1969

    CAS  Google Scholar 

  15. Schayer RW: Induced synthesis of histamine, microcirculatory regulation and the mechanism of action of the adrenal glucocorticoid hormones, in Kallos P, et al (eds): Progress in Allergy. New York, S Karger, 1963, pp 187–212

    Google Scholar 

  16. Grzglewski RJ: Effects of anti-inflammatory steroids on arachidonate cascade. Adv Inflammation Res 1:505–513, 1979

    Google Scholar 

  17. Greaves MW, McDonald-Gibson W: Inhibition of prostaglandin biosynthesis by corticosteroids. Br Med J 2:83–84, 1972

    PubMed  CAS  Google Scholar 

  18. Hammond CV, Hammond MD, Taylor WA: Selective inhibition by betamethasone of allergen-induced release of SRS-A from human lung. Int Arch Allergy Appl Immunol 67:284–286, 1982

    PubMed  CAS  Google Scholar 

  19. Oertel H, Kaliner M: The biologic activity of mast cell granules in rat skin: Effects of adrenocorticoids on late-phase inflammatory responses induced by mast cell granules. J Allergy Clin Immunol 68:238–245, 1981

    Article  PubMed  CAS  Google Scholar 

  20. Zweifach BW, Shorr E, Black MM: The influence of the adrenal cortex on behavior of the terminal vascular bed. Ann NY Acad Sci 56:626–633, 1953

    Article  PubMed  CAS  Google Scholar 

  21. Claman HN: Corticosteroids and lymphoid cells. N Engl J Med 287:388–397, 1972

    PubMed  CAS  Google Scholar 

  22. Stevenson HC, Fauci AS: Effects of corticosteroids on the function and distribution of human lymphocytes, in Franklin EC (ed): Clinical Immunology Update: Reviews for Physicians. New York, Elsevier Science Publishing Co., Inc., 1981, pp 337–355

    Google Scholar 

  23. Weissmann G, Thomas L: Studies on lysosomes. I. The effects of endotoxin, endotoxin tolerance, and cortisone on the release of acid hydrolysis from a granule fraction of rabbit liver. J Exp Med 116:433–450, 1962

    Article  PubMed  CAS  Google Scholar 

  24. Ellul-Micallef R, Borthwick RC, McHardy JR: The effect of oral prednisolone on gas exchange in chronic bronchial asthma. Br J Clin Pharmacol 2:479–182, 1980

    Google Scholar 

  25. Logsdon PJ, Middleton E, Coffee RG: Stimulation of leukocyte adenyl cyclase by hydrocortisone and isoproterenol in asthmatic and nonasthmatic subjects. J Allergy Clin Immunol 50:45–56, 1972

    Article  PubMed  CAS  Google Scholar 

  26. Fraser CM, Venter JC: The synthesis of β-adrenergic receptors in cultured human lung cells: Induction by glucocorticoids. Biochem Biophys Res Commun 94:390–397, 1980

    Article  PubMed  CAS  Google Scholar 

  27. Thompson EB, Lippman ME: Mechanisms of action of glucocorticoids. Metabolism 23:159–202, 1974

    Article  PubMed  CAS  Google Scholar 

  28. Middleton E: Mechanism of action of corticosteroids, in Stein M (ed): New Directions in Asthma. Park Ridge, Ill., American College of Chest Physicians, 1975, pp 433–446

    Google Scholar 

  29. Geddes BA, Lefcoe NM: Respiratory smooth muscle relaxing effect of commercial steroid preparations. Am Rev Respir Dis 107:395–399, 1973

    PubMed  CAS  Google Scholar 

  30. Frigas E, Loegering DA, Gleich GJ: Cytotoxic effects of the guinea pig eosinophil major basis protein on tracheal epithelium. Lab Invest 42:35–43, 1980

    PubMed  CAS  Google Scholar 

  31. Schatz M, Wasserman S, Patterson R: Eosinophils and immunologic lung disease. Med Clin North Am 65:1055–1071, 1981

    PubMed  CAS  Google Scholar 

  32. Gleich GJ, Loegering DA, Frigas E, Wasson DL, Solley GO, Mann KG: The major basic protein of the eosinophil granule: Physiochemical properties, localization and function, in Mahmous AAF, Austen KF (eds): The Eosinophil in Health and Disease. New York, Grune & Stratton, 1980, pp 79–97

    Google Scholar 

  33. Hirsh SR: The role of mucus in asthma, in Stein M, (ed): New Directions in Asthma. Park Ridge, Ill., American College of Chest Physicians, 1975, pp 351–373

    Google Scholar 

  34. Collins JV, Clark TJH, Brow D, Townsend J: The use of corticosteroids in treatment of acute asthma. Q J Med 44:259–273, 1975

    PubMed  CAS  Google Scholar 

  35. Pierson WE, Bierman CW, Kelley VC: A double-blind trial of corticosteroid therapy in status asthmaticus. Pediatrics 54:282–288, 1974

    PubMed  CAS  Google Scholar 

  36. Fanta CH, Rossing TH, McFadden ER: Glucocorticoids in acute asthma. Am Rev Respir Dis 125(suppl 3): 94, 1982

    Google Scholar 

  37. Loren ML, Chai H, Leung P, Rohr C, Brenner AM: Corticosteroids in the treatment of acute exacerbations of asthma. Ann Allergy 45:67–71, 1980

    PubMed  CAS  Google Scholar 

  38. Klaustermeyer WB, Hale FC: The physiologic effect of an intravenous glucocorticoid in bronchial asthma. Ann Allergy 37:80–86, 1976

    PubMed  CAS  Google Scholar 

  39. Editorial: Corticosteroids in acute severe asthma. Lancet 2:166–167, 1975

  40. Medical Research Council: Cortisone acetate in status asthmaticus. Lancet 2:803–806, 1956

    Google Scholar 

  41. Grant IWB: Are corticosteroids necessary in the treatment of severe acute asthma. Br J Dis Chest 76:125–129, 1981

    Google Scholar 

  42. Holgate ST, Baldwin CJ: Beta-adrenergic agonists resistance in normal human airways. Lancet 2:375–377, 1977

    Article  PubMed  CAS  Google Scholar 

  43. Shenfield GM, Hodson ME, Clarke SW, Paterson JW: Interactions of corticosteroids and catecholamines in the treatment of asthma. Thorax 30:430–435, 1975

    PubMed  CAS  Google Scholar 

  44. Kattan M, Gurwitz D, Levison H: Corticosteroids in status asthmaticus. J Pediatr 96:596–599, 1980

    Article  PubMed  CAS  Google Scholar 

  45. Luksza AR: Acute severe asthma treated without steroids. Br J Dis Chest 76:15–19, 1982

    PubMed  CAS  Google Scholar 

  46. Luksza AR: A new look at adult asthma. Br J Dis Chest 76:11–14, 1982

    PubMed  CAS  Google Scholar 

  47. Dwyer J, Lazarus L, Hickie JB: A study of cortisol metabolism in patients with chronic asthma. Aust Ann Med 16:297–302, 1967

    PubMed  CAS  Google Scholar 

  48. Rose JQ, Nickelson JA, Middleton E, Yarchak AM, Park BH, Jusko WJ: Prednisolone disposition in steroid-dependent asthmatics. J Allergy Clin Immunol 66:366–373, 1980

    Article  PubMed  CAS  Google Scholar 

  49. Collins JV, Harris PWR, Clark TJH, Townsend J: Intravenous corticosteroids in treatment of acute bronchial asthma. Lancet 1:1047–1049, 1980

    Google Scholar 

  50. Morris HG: Rational use of corticosteroid therapy, in Berman BA, MacDonnel KF (eds): Differential Diagnosis and Treatment of Pediatric Allergy. Boston, Little Brown, 1981, pp 267–284

    Google Scholar 

  51. McFadden ER, Kiser R, deGroot WJ, Holmes B, Kiker R, Viser G: A controlled study of the effects of single doses of hydrocortisone on the resolution of acute attacks of asthma. Am J Med 60:52–59, 1976

    Article  PubMed  Google Scholar 

  52. Harfi H, Hanissian AS, Crawford LV: Treatment of status asthmaticus in children with high doses and conventional doses of methylprednisolone. Pediatrics 61:829–831, 1978

    PubMed  CAS  Google Scholar 

  53. Krause HA, Santiago SM, Klaustermeyer WB: Intravenously given methylprednisolone in refractory asthma. West J Med 132:106–110, 1980

    Google Scholar 

  54. Easton J, Hilman B, Shapiro G, Weinberger M, Anderson J, Buckley J, Eggleston P, Bierman CW: Management of asthma. Pediatrics 68:874–879, 1981

    Google Scholar 

  55. Nassif EG, Weinberger M, Thompson R, Huntley W: The value of maintenance theophylline in steroid-dependent asthma. N Engl J Med 304:71–75, 1981

    PubMed  CAS  Google Scholar 

  56. The Boston Collaborative Drug Surveillance Program: Acute adverse reactions to prednisone in regulation to dosage. Clin Pharmacol Ther 13:694–698, 1972

    Google Scholar 

  57. Vince DJ: Nodular panniculitis after massive prednisone therapy. Can Med Assoc J 79:840–841, 1958

    PubMed  CAS  Google Scholar 

  58. Dees SC, McKay HW: Occurrence of pseudotumor cerebri (benign intracranial hypertension) during treatment of children with asthma by adrenal steroids: Report of three cases. Pediatrics 23:1143–1151, 1959

    PubMed  CAS  Google Scholar 

  59. Neville BGR, Wilson J: Benign intracranial hypertension following corticosteroid withdrawal in childhood. Br Med J 3:554–556, 1970

    Article  PubMed  CAS  Google Scholar 

  60. Fraser FC, Walker BE, Fainstat TD: The experimental production of cleft palate with cortisone and other hormones. J Cell Physiol 43(suppl 1):237–259, 1954

    CAS  Google Scholar 

  61. Fraser FC: Second International Conference on Congenital Malformations. New York, International Medical Congress, 1963

    Google Scholar 

  62. Blackburn WR, Kaplan HS, McKay DG: Morphologic changes in the developing rat placenta following prednisolone administration. Am J Obstet Gynecol 92:234–246, 1965

    PubMed  CAS  Google Scholar 

  63. Fainstat T: Cortisone induced congenital cleft palate in rabbits. Endocrinology 55:502–508, 1954

    PubMed  CAS  Google Scholar 

  64. Liggins GC: Premature parturition after infusion of corticotropin or cortisol into foetal lambs. J Endocrinol 42:323–329, 1968

    PubMed  CAS  Google Scholar 

  65. Schatz M, Patterson R, Zeitz S, O’Rourke J, Melam H: Corticosteroid therapy for the pregnant asthmatic patient. J Am Med Assoc 233:804–807, 1975

    Article  CAS  Google Scholar 

  66. Plumpton FS, Besser GM, Cole PV: Corticosteroid treatment and surgery. Anesthesia 24:3–18, 1969

    Article  CAS  Google Scholar 

  67. Kehlet H: A rational approach to dosage and preparation of parenteral glucocorticoid substitution therapy during surgical procedures. Acta Anesthesiol Scand 19:260–264, 1975

    Article  CAS  Google Scholar 

  68. Symreng T, Karlberg BE, Kagedal B, Schildt B: Physiological cortisol substitution of long-term steroid-dependent patients undergoing major surgery. Br J Anaesth, 53:949–954, 1981

    Article  PubMed  CAS  Google Scholar 

  69. Sahn SA: Corticosteroids in chronic bronchitis and pulmonary emphysema. Chest 73:389–396, 1978

    Article  PubMed  CAS  Google Scholar 

  70. Albert RK, Martin TR, Lewis SW: Controlled clinical trial of methylprednisolone in patients with chronic bronchitis and acute respiratory insufficiency. Ann Intern Med 92:753–758, 1980

    PubMed  CAS  Google Scholar 

  71. Mendella LA, Manfreda J, Warren CPW, Anthonisen NR: Steroid response in stable chronic obstructive pulmonary disease. Ann Intern Med 96:17–22, 1982

    PubMed  CAS  Google Scholar 

  72. Good RA, Vernier RL, Smith RT: Serious untoward reactions to therapy with cortisone and adrenocorticotropin in pediatric practice. I and II. Pediatrics 19:95–118, 272–284, 1957

    PubMed  CAS  Google Scholar 

  73. Melby JC, Silber RH: Clinical pharmacology of water soluble corticosteroid esters. Am Pract 12:156–161, 1961

    Google Scholar 

  74. Jubiz W, Meikle AW: Alterations of glucocorticoid actions by other drugs and disease states. Drugs 18:113–121, 1979

    Article  PubMed  CAS  Google Scholar 

  75. Tulin-Silver J, Schteingart DE, Mathews KP: Effect of theophylline on cortisol secretion. J Allergy Clin Immunol 67:45–50, 1981

    Article  PubMed  CAS  Google Scholar 

  76. Brooks SM, Sholiton LJ, Werk EE, Altenau P: The effects of ephedrine and theophylline on dexamethasone metabolism in bronchial asthma. J Clin Pharmacol 17:308–318, 1977

    PubMed  CAS  Google Scholar 

  77. Hellman L, Bradlow HL, Zumoff B, Gallagher TF: The influence of thyroid hormone on hydrocortisone production and metabolism. J Clin Endocrinol Metab 21:1231–1247, 1961

    PubMed  CAS  Google Scholar 

  78. Lange K, Slobody L, Strang RH: Treatment of nephrotic syndrome with interrupted ACTH or cortisone therapy. Proc Soc Exp Biol Med 82:315–317, 1953

    PubMed  CAS  Google Scholar 

  79. Siegel SC, Lovin BJ, Ely RS, Kelley VC: Adrenal function in allergy. III. Effect of prolonged intermittent steroid therapy in allergic children. Pediatrics 24:434–447, 1959

    PubMed  CAS  Google Scholar 

  80. Malone DNS, Grant IWB, Percy-Robb, IW: Hypothalamo-pituitary-adrenal function in asthmatic patients receiving long-term corticosteroid therapy. Lancet 2:733–735, 1970

    Article  PubMed  CAS  Google Scholar 

  81. Harter JG, Reddy WJ, Thorn GW: Studies on an intermittent corticosteroid dosage regimen. N Engl J Med 269:591–596, 1963

    PubMed  CAS  Google Scholar 

  82. Siegel SC: Corticosteroids and ACTH in the management of the atopic child. Pediatr Clin North Am 16:287–304, 1969

    PubMed  CAS  Google Scholar 

  83. Siegel SC, Goldberg M, Richards W, Busser RJ: Effects of alternate-day corticosteroid therapy on linear growth in children with intractable asthma. Isr J Med Sci 6:743, 1970

    Google Scholar 

  84. Axelrod L: Glucocorticoid therapy. Medicine 55:39–65, 1975

    Google Scholar 

  85. Soyka LF: Alternate-day corticosteroid therapy. Adv Pediatr 19:47–70, 1962

    Google Scholar 

  86. Soyka LF: Treatment of nephrotic syndrome in childhood—Use of alternate-day regimen. Am J Dis Child 113:693–701, 1967

    PubMed  CAS  Google Scholar 

  87. Morris HG, Neuman I, Ellis EF: Plasma steroid concentrations during alternate-day treatment with prednisone. J Allergy Clin Immunol 54:350–358, 1974

    Article  Google Scholar 

  88. Shapiro GG, Tattoni DS, Kelley VC, Pierson WE, Bierman CW: Growth, pulmonary, and endocrine function in chronic asthma patients on daily and alternate-day adrenocorticosteroid therapy J. Allergy Clin Immunol 57:430–439, 1976

    Article  CAS  Google Scholar 

  89. Reimer LG, Morris HG, Ellis EF: Growth of asthmatic children during treatment with alternate-day steroids. J Allergy Clin Immunol 55:224–231, 1975

    Article  PubMed  CAS  Google Scholar 

  90. O’Neill WM, Etheridge WB, Bloomer A: High-dose corticosteroids: Their use in treating idiopathic rapidly progressive glomerulonephritis. Arch Intern Med 139:514–518, 1979

    Article  PubMed  Google Scholar 

  91. Kimberly RP, Lockshin MD, Sherman RL, McDougal JS, Inman RD, Christian CL: High-dose intravenous methylprednisolone pulse therapy in systemic lupus erythematosus. Am J Med 70:817–824, 1981

    Article  PubMed  CAS  Google Scholar 

  92. Johnson RB, Lazarus GS: Pulse therapy: Therapeutic efficacy in the treatment of pyoderma gangrenosum. Arch Dermatol 18:76–84, 1982

    Article  Google Scholar 

  93. Miller JJ: Prolonged use of large intravenous steroid pulses in the rheumatic diseases in children. Pediatrics 65:989–994, 1980

    PubMed  Google Scholar 

  94. Liebling MR, Lieb E, McLaughlin K: Pulse methylprednisolone in rheumatoid arthritis: A double-blind cross-over trial. Ann Intern Med 94:21–26, 1981

    PubMed  CAS  Google Scholar 

  95. Hess EV, Kammen PL: Pulse therapy in rheumatoid arthritis. Ann Intern Med 94:128–129, 1981

    PubMed  CAS  Google Scholar 

  96. Moses RE, McCormick A, Mickey W: Fatal arrhythmia after pulse methylprednisolone therapy. Ann Intern Med 95:781–782, 1981

    PubMed  CAS  Google Scholar 

  97. Klinefelter HF, Winkenwerder WL, Bledsoe T: Single daily dose prednisone therapy J Am Med Assoc 241:2721–2723, 1979

    Article  CAS  Google Scholar 

  98. Myles AB, Schiller LFG, Glass D, Daily JR: Single daily dose corticosteroid treatment. Ann Rheum Dis 35:73–76, 1976

    Article  PubMed  CAS  Google Scholar 

  99. Ellis EF, Morris HG, Kiechel F, Pollock JD, Strang LJ: Short-term efficacy and side effects of cloprednol in children with asthma. J Clin Pharmacol 19:675–683, 1979

    PubMed  CAS  Google Scholar 

  100. Gavani UD, Hyde JS, Khurana S, Manaligod LM: Long-term cloprednol use in chronic asthma. J Am Med Assoc 242:2679–2682, 1979

    Article  CAS  Google Scholar 

  101. Siegel SC, Heimlich EM, Richards W, Kelley VC: Adrenal function in allergy. IV. Effect of dexamethasone aerosols in asthmatic children. Pediatrics 33:245–250, 1964

    PubMed  CAS  Google Scholar 

  102. Klein R, Waldman D, Kershnar H, Berger W, Coulson A, Katz R, Rachelefsky GS, Siegel S: Treatment of chronic childhood asthma with beclomethasone dipropionate aerosols. I. A double-blind crossover trial in non-steroid dependent patients. Pediatrics 60:7–13, 1977

    PubMed  CAS  Google Scholar 

  103. Kershnar H, Klein R, Waldman D, Berger W, Rachelefsky G, Katz R, Siegel S: Treatment of chronic childhood asthma with beclomethasone dipropionate aerosols. II. Effect on pituitary-adrenal function after substitution for oral corticosteroids. Pediatrics 62:189–197, 1978

    PubMed  CAS  Google Scholar 

  104. Andersson E, Smidt CM, Sikjaer B, Ainge G, Poynter D: Bronchial biopsies after beclomethasone dipropionate aerosol. Br J Dis Chest 77:35–43, 1977

    Article  Google Scholar 

  105. DeCotis BA, Settipane GA: The effect of inhaled beclomethasone on serum immunoglobulins. Proc N Engl Soc Allergy 2:153–156, 1981

    Article  Google Scholar 

  106. Soderbert-Warner M, Siegel S, Katz R, Rachelefsky G: Treatment of chronic childhood asthma with beclomethasone dipropionate aerosols (BDA). IV. Long-term effects on growth. J Allergy Clin Immunol 63:164, 1979 (abstract 99).

    Google Scholar 

  107. Wyatt R, Waschek J, Weinberger M, Sherman B: Effects of inhaled beclomethasone dipropionate and alternate-day prednisone on pituitary-adrenal function in children with chronic asthma. N Engl J Med 299:1387–1392, 1978

    Article  PubMed  CAS  Google Scholar 

  108. Vaz R, Senior B, Morris M, Binkiewicz A: Adrenal effects of beclomethasone inhalation therapy in asthmatic children. J Pediatr 100:660–662, 1982

    Article  PubMed  CAS  Google Scholar 

  109. Mellis CM, Phelan DD: Asthma deaths in children—A continuing problem. Thorax 32:29–34, 1977

    PubMed  CAS  Google Scholar 

  110. Harris DM, Martin LE, Harrison C, Jack D: The effect of oral and inhaled beclomethasone dipropionate on adrenal function. Clin Allergy 3:243–248, 1973

    Article  PubMed  CAS  Google Scholar 

  111. Mygind N, Hansen I: Beclomethasone dipropionate aerosol effect on the adrenals in normal persons. Acta Allergol 28:211–218, 1973

    PubMed  CAS  Google Scholar 

  112. Blaiss M, Herrod H, Crawford L, Lieberman P: Beclomethasone dipropionate aerosol: Hematological and immunological effects. Ann Allergy 48:210–214, 1982

    PubMed  CAS  Google Scholar 

  113. Nassif E, Weinberger M, Thompson R, Sherman B: Effects of continuous corticosteroid therapy for children with chronic asthma. J Allergy Clin Immunol 65:219–220, 1980 (abstract 183)

    Google Scholar 

  114. Godfrey S, Konig, P: Treatment of childhood asthma for 13 months and longer with beclomethasone dipropionate aerosol. Arch Dis Child 49:591–596, 1974

    PubMed  CAS  Google Scholar 

  115. Spitzer SA, Kaufman H, Koplovitz A, Topilsky M, Blum I: Beclomethasone dipropionate and chronic asthma. The effect of long-term aerosol administration on the hypothalamic-piruitary-adrenal axis after substitution for oral therapy with corticosteroids. Chest 70:38–42, 1976

    Article  PubMed  CAS  Google Scholar 

  116. Spector SL: Response of severe corticosteroid-dependent asthmatic patients to beclomethasone dipropionate aerosol, in Farr RS, Middleton EM Jr, Spector SL (eds): Recent Advances in Asthma Therapy. Miami, Symposia Specialists, 1976, pp 75–80

    Google Scholar 

  117. Sherman B, Weinberger M, Chen-Walden H, Wendt H: Further studies of the effects of inhaled glucocorticoids on pituitary-adrenal function in healthy adults. J Allergy Clin Immunol 69:208–212, 1982

    Article  PubMed  CAS  Google Scholar 

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Siegel, S.C. Adrenal corticosteroids in the treatment of asthma. Clin Rev Allerg 1, 123–146 (1983). https://doi.org/10.1007/BF02991321

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