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Theophylline

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References

  1. Greene JA, Paul WO, Fallier AE: The action of theophylline with ethylene diamine on intrathecal and venous pressures in cardiac failure and on bronchial obstruction in cardiac failure and in bronchial asthma. J Am Med Assoc 109:1712, 1937

    CAS  Google Scholar 

  2. Herrmann GR, Aynesworth MB, Marlin J: Successful treatment of persistent extreme dyspnea, status asthmaticus: Use of theophylline ethylene diamine (aminophylline USP). J Lab Clin Med 23:135, 1937

    Google Scholar 

  3. May CD: History of the introduction of theophylline into the treatment of asthma. Clin Allergy 4:211–217, 1974

    Article  PubMed  CAS  Google Scholar 

  4. Ellis EF: Theophylline and derivatives, in Middleton E Jr, Reed CE, Ellis EF (eds): Allergy: Principles and Practice, St. Louis, CV Mosby, 1978, pp 434–453

    Google Scholar 

  5. Armand J, Deplante D, Badinand A: Theophylline toxicity in children. Lyon Med 229:485, 1973

    CAS  Google Scholar 

  6. Ogilvie RI: Clinical pharmacokinetics of theophylline. Clin Pharmacol 3:267, 1978

    Article  CAS  Google Scholar 

  7. Weinberger M, Hendeles L, Ahrens R: Clinical pharmacology of drugs used for asthma. Pediatr Clin North Am 28:47–75, 1981

    PubMed  CAS  Google Scholar 

  8. Weinberger M, Hendeles L, Bighley L: The relation of product formulation to absorption of oral theophylline. N Engl J Med 299:852–857, 1978

    PubMed  CAS  Google Scholar 

  9. Kampa IS, Dunikoski LK Jr, Jarzabek JI, Grubesich D: Comparison of three assay procedures for theophylline determination. Ther Drug Monit 1:249–256, 1979

    Article  PubMed  CAS  Google Scholar 

  10. Boeck RL, Frith EM, Simons FER: Comparison of a high performance liquid chromatographic and an enzyme immunoassay technique for quantitation of theophylline in serum. Ther Drug Monit 1:65–73, 1979

    Google Scholar 

  11. Cornish HH, Christman AA: A study of the metabolism of theobromine, theophylline, and caffeine in man. J Biol Chem 228:315–323, 1957

    PubMed  CAS  Google Scholar 

  12. Ellis EF, Koysooko R, Levy G: Pharmacokinetics of theophylline in children with asthma. Pediatrics 58:542–547, 1976

    PubMed  CAS  Google Scholar 

  13. Jusko WJ, Gardner MJ, Mangione A, Schentag JJ, Koup, JR, Vance JW: Factors affecting theophylline clearances: Age, tobacco, marijuana, cirrhosis, congestive heart failure, obesity, oral contraceptives, benzodiazepines, barbiturates, and ethanol. J Pharm Sci 68:1358–1366, 1979

    Article  PubMed  CAS  Google Scholar 

  14. Gal P, Jusko WJ, Yurchak AM, Franklin BA: Theophylline disposition in obesity. Clin Pharmacol Ther 23:438–444, 1978

    PubMed  CAS  Google Scholar 

  15. Blouin RA, Elgert JF, Bauer LA: Theophylline clearance: Effect of marked obesity. Clin Pharmacol Ther 28:619–623, 1980

    PubMed  CAS  Google Scholar 

  16. Monks TJ, Caldwell J, Smith RL: Influence of methylxanthine-containing foods on theophylline metabolism and kinetics. Clin Pharmacol Ther 26:513–524, 1979

    PubMed  CAS  Google Scholar 

  17. Kappas A, Anderson KE, Conney AH, Alvares AP: Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man. Clin Pharmacol Ther 20:643–653, 1976

    PubMed  CAS  Google Scholar 

  18. Kappas A, Alvares AP, Anderson KE, Pantuck EJ, Pantuck CB, Chang R, Conney AH: Effect of charcoal-broiled meat on antipyrine and theophylline metabolism. Clin Pharmacol Ther 23:445–450, 1978

    PubMed  CAS  Google Scholar 

  19. Jusko WJ, Scentag JJ, Clark JH, Gardner M, Yurchak AM: Enhanced biotransformation of theophylline in marihuana and tobacco smokers. Clin Pharmacol Ther 24:406–410, 1978

    CAS  Google Scholar 

  20. Grygiel JJ, Birkett DJ: Cigarette smoking and theophylline clearance and metabolism. Clin Pharmacol Ther 30:491–196, 1981

    PubMed  CAS  Google Scholar 

  21. Powell JR, Thiercelin J-F, Vozeh S, Sansom L, Reigelman S: The influence of cigarette smoking and sex on theophylline disposition. Am Rev Respir Dis 116:17–23, 1977

    PubMed  CAS  Google Scholar 

  22. Marquis J, Carruthers SG, Spence JD, Brownstone YS, Toogood JH: Phenytoin-theophylline interaction. N Engl J Med 307:1189, 1982

    PubMed  CAS  Google Scholar 

  23. Weinberger M, Hudgel D, Spector S, Chidsey C: Inhibition of theophylline clearance by troleandomycin. J Allergy Clin Immunol 59:228–231, 1977

    Article  PubMed  CAS  Google Scholar 

  24. LaForce CF, Miller MF, Chai H: Effect of erythromycin on theophylline clearance in asthmatic children. J Pediatr 99:153–156, 1981

    Article  PubMed  CAS  Google Scholar 

  25. Prince RA, Wing DS, Weinberger MM, Hendeles LS, Riegelman S: Effect of erythromycin on theophylline kinetics. J Allergy Clin Immunol 68:427–431, 1981

    Article  PubMed  CAS  Google Scholar 

  26. Zarowitz BJM, Szefler SJ, Lasezkay GM: Effect of erythromycin base on theophylline kinetics. Clin Pharmacol Ther 29:601–605, 1981

    PubMed  CAS  Google Scholar 

  27. Jackson JE, Powell JR, Wandell M, Bently J, Dorr R: Cimetidine decreases theophylline clearance. Am Rev Respir Dis 123:615–617, 1981

    PubMed  CAS  Google Scholar 

  28. Roberts RK, Grice J, Wood L, Petroff V, McGuffie C: Cimetidine impairs the elimination of theophylline and antipyrine. Gastroenterology 81:19–21, 1981

    PubMed  CAS  Google Scholar 

  29. Weinberger M, Smith G, Milavetz G, Hendeles L: Decreased theophylline clearance due to cimetidine. N Engl J Med 304:672, 1981

    PubMed  CAS  Google Scholar 

  30. Conrad KA, Nyman DW: Effects of metoprolol and propranolol on theophylline elimination. Clin Pharmacol Ther 28:463–167, 1980

    PubMed  CAS  Google Scholar 

  31. Renton KW, Gray JD, Hall RI: Decreased elimination of theophylline after influenza vaccination. Can Med Assoc J 123:288–290, 1980

    PubMed  CAS  Google Scholar 

  32. Mangione A, Imhoff TE, Lee RV, Shum LY, Jusko WJ: Pharmacokinetics of theophylline in hepatic disease. Chest 73:616–622, 1978

    Article  PubMed  CAS  Google Scholar 

  33. Piafsky KM, Sitar DS, Rangno RE, Ogilvie RI: Theophylline disposition in patients with hepatic cirrhosis. N Engl J Med 296:1495–1497, 1977

    PubMed  CAS  Google Scholar 

  34. Jenne JW, Chick TW, Miller BA, Strickland RD: Apparent theophylline half-life fluctuations during treatment of acute left ventricular failure. Am J Hosp Pharm 34:408–409, 1977

    PubMed  CAS  Google Scholar 

  35. Piafsky KM, Sitar DS, Rangno RE, Ogilvie RI: Theophylline kinetics in acute pulmonary edema. Clin Pharmacol Ther 21:310–316, 1977

    PubMed  CAS  Google Scholar 

  36. Vicuna N, McNay JL, Ludden TM, Schwertner H: Impaired theophylline clearance in patients with cor pulmonale. Br J Clin Pharmacol 7:33–37, 1979

    PubMed  CAS  Google Scholar 

  37. Chang KC, Bell TD, Lauer BA, Chai H: Altered theophylline pharmacokinetics during acute respiratory viral illness. Lancet 1:1132–1133, 1978

    Article  PubMed  CAS  Google Scholar 

  38. Vozeh S, Powell JR, Riegelman S, Costello JF, Sheiner LB, Hopewell PC: Changes in theophylline clearance during acute illness. J Am Med Assoc 240:1882–1884, 1978

    Article  CAS  Google Scholar 

  39. Weinberger M, Ginchansky E: Dose-dependent kinetics of theophylline disposition in asthmatic children. J Pediatr 91:820–824, 1977

    Article  PubMed  CAS  Google Scholar 

  40. Jenne JW, Wyze MS, Rood FS: Pharmacokinetics of theophylline: Application to adjustment of the clinical dose of aminophylline. Clin Pharmacol Ther 13:349, 1972

    PubMed  CAS  Google Scholar 

  41. Sarrazin E, Hendeles L, Weinberger M, Muir K, Riegelman S: Dose-dependent kinetics for theophylline: Observations among ambulatory asthmatic children. J Pediatr 97:825–828,1980

    Article  PubMed  CAS  Google Scholar 

  42. Eney RD, Goldstein EO: Compliance of chronic asthmatics with oral administration of theophylline as measured by serum and salivary levels. Pediatrics 57:513–517, 1976

    PubMed  CAS  Google Scholar 

  43. Sublett JL, Pollard SJ, Kadlec GJ, Karibo JM: Non-compliance in asthmatic children: A study of theophylline levels in a pediatric emergency room population. Ann Allergy 43:95–97, 1979

    PubMed  CAS  Google Scholar 

  44. Green ER, Green AW, Lane R, Slaughter R, Middleton E Jr: Absorption characteristics of sustained release theophylline capsules administered in applesauce. J Pediatr 98:832–834, 1981

    Article  PubMed  CAS  Google Scholar 

  45. Weinberger M, Hendeles L, Wong I, Vaughan L: Relationship of formulation and dosing interval to fluctuation of serum theophylline concentration in children with chronic asthma. J Pediatr 99:145–152, 1981

    Article  PubMed  CAS  Google Scholar 

  46. Simons FER, Luciuk GH, Simons KJ: Sustained-release theophylline for treatment of asthma in preschool children. Am J Dis Child 136:790–793, 1982

    PubMed  CAS  Google Scholar 

  47. Dederich RA, Szefler SJ, Green ER: Intrasubject variation in sustained-release theophylline absorption. J Allergy Clin Immunol 67:465–471, 1981

    Article  PubMed  CAS  Google Scholar 

  48. Mitenko PA, Ogilvie RI: Rational intravenous doses of theophylline. N Engl J Med 289:600–603, 1973

    PubMed  CAS  Google Scholar 

  49. Maselli R, Casal GL, Ellis EF: Pharmacologic effects of intravenously administered aminophylline in asthmatic children. J Pediatr 76:777–782, 1970

    Article  PubMed  CAS  Google Scholar 

  50. Nicholson DP, Chick TW: A re-evaluation of parenteral aminophylline. Am Rev Respir Dis 108:241–247, 1973

    PubMed  CAS  Google Scholar 

  51. Rachelefsky GS, Katz RM, Siegel SC: A sustained release theophylline preparation: Efficacy in childhood asthma with low serum theophylline levels. Ann Allergy 40:252–257, 1978

    PubMed  CAS  Google Scholar 

  52. Ogilvie RI: Monitoring plasma theophylline concentrations. Ther Drug Monit 2:111–117,1980

    Article  PubMed  CAS  Google Scholar 

  53. Hendeles L, Weinberger M, Johnson G: Monitoring serum theophylline levels. Clin Pharmacokinet 3:294–312, 1978

    Article  PubMed  CAS  Google Scholar 

  54. Koysooko R, Ellis EF, Levy G: Relationship between theophylline concentration in plasma and saliva of man. Clin Pharmacol Ther 15:454–460, 1974

    PubMed  CAS  Google Scholar 

  55. Jonkman JHG, Koeter GH, Schoenmaker R, deVries K, Greving JE, deZeeuw RA: Correlation of serum and saliva theophylline concentrations after administration of a sustained release preparation. Eur J Clin Pharmacol 20:73–78, 1981

    Article  PubMed  CAS  Google Scholar 

  56. Leung P, Kalisker A, Bell TD: Variation in theophylline clearance rate with time in chronic childhood asthma. J Allergy Clin Immunol 59:440–444, 1977

    Article  PubMed  CAS  Google Scholar 

  57. Nicklas RA, Whitehurst VE, Donohoe RF: Combined use of beta-adrenergic agonists and methyl xanthines. N Engl J Med 307:557–558, 1982

    PubMed  CAS  Google Scholar 

  58. Snodgrass W, Sawyer D, Conner CS, Rumack BH, Peterson RG, Sullivan, Jr., JB: Asymptomatic theophylline overdose. Drug Intell Clin Pharm 14:783–785, 1980

    Google Scholar 

  59. Sintek C, Hendeles L, Weinberger M: Inhibition of theophylline absorption by activated charcoal. J Pediatr 94:314–316, 1979

    Article  PubMed  CAS  Google Scholar 

  60. Berg MJ, Berlinger WG, Goldberg MJ, Spector R, Johnson GF: Acceleration of the body clearance of phenobarbital by oral activated charcoal. N Engl J Med 307:642–644, 1982

    Article  PubMed  CAS  Google Scholar 

  61. Espinosa-Melendez E, Chang TMS: ACAC (albumin-collodion coated activated charcoal) hemoperfusion: In-vitro removal and clearance of theophylline. J Dial 4:21–29, 1980

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. From the Department of Pediatrics, State University of New York at Buffalo School of Medicine, Buffalo, New York

    Elliot F. Ellis MD

  2. Children’s Hospital, 219 Bryant Street, 14222, Buffalo, NY

    Elliot F. Ellis MD

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  1. Elliot F. Ellis MD
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Ellis, E.F. Theophylline. Clin Rev Allerg 1, 73–85 (1983). https://doi.org/10.1007/BF02991318

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