Skip to main content
Log in

Venom immunotherapy for stinging insect allergy

  • Published:
Clinical Reviews in Allergy Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Waterhouse AT: Bee sting and anaphylaxis. Lancet ii:946, 1914

    Article  Google Scholar 

  2. Braun LIB: Notes on desensitization of a patient hypersensitive to bee stings. S Afr Med Rec 23:408, 1925

    Google Scholar 

  3. Benson RL, Semenov H: Allergy in its relation to the bee sting. J Allergy 1:105–116, 1930

    Article  Google Scholar 

  4. Benson RL: Diagnosis of hypersensitiveness to the bee and to the mosquito. Arch Int Med 64:1306–1327, 1939

    Google Scholar 

  5. Mueller HL: Further experiences with severe allergic reactions to insect sting. N Engl J Med 261:374–377, 1959

    PubMed  CAS  Google Scholar 

  6. Mueller HL, Schmid WH, Rubinsztain R: Stinging-insect hypersensitivity: A 20-year study of immunologic treatment. Pediatrics 55:530–533, 1975

    PubMed  CAS  Google Scholar 

  7. Frazier CA, Barr SE: Correspondence J Allergy Clin Immunol 59:402, 1977

    Article  PubMed  CAS  Google Scholar 

  8. Insect Allergy Committee of the American Academy of Allergy: Insect sting allergy: Cooperative study. JAMA 193:115–120, 1965

    Google Scholar 

  9. Schwartz HJ: Skin sensitivity in insect allergy. JAMA 194:113–115, 1965

    Article  Google Scholar 

  10. Bernton HS, Brown H: Studies on the Hymenoptera. I. Skin reactions of normal persons to honeybee (Apis mellifera) extract. J Allergy 36:315–320, 1965

    Article  Google Scholar 

  11. Sobotka AK, Valentine MD, Benton AW, et al: Allergy to insect stings. I. Diagnosis of IgE-mediated Hymenoptera sensitivity by venom-induced histamine release. J Allergy Clin Immunol 53:170–184, 1974

    Article  PubMed  CAS  Google Scholar 

  12. Torsney PJ: Treatment failure: Insect desensitization. J Allergy Clin Immunol 52:303–306, 1973

    Article  PubMed  CAS  Google Scholar 

  13. Reisman RE: Stinging insect allergy-treatment failures. J Allergy Clin Immunol 52:257–258, 1973

    Article  PubMed  CAS  Google Scholar 

  14. Lichtenstein LM, Valentine MD, Sobotka AK: A case for venom treatment in anaphylactic sensitivity to Hymenoptera sting. N Engl J Med 290:1223–1227, 1974

    Article  PubMed  CAS  Google Scholar 

  15. Loveless MH: Immunization in wasp-sting allergy through venom-repositories and periodic insect stings. J Immunol 89:204–215, 1962

    PubMed  CAS  Google Scholar 

  16. Busse WW, Reed CE, Lichtenstein LM, et al: Immunotherapy in bee-sting anaphylaxis. Use of honeybee venom. JAMA 231:1154–1156, 1974

    Article  Google Scholar 

  17. Hunt KJ, Valentine MD, Sobotka AK, et al: A controlled trial of immunotherapy in insect hypersensitivity. N Engl J Med 299:157–161, 1978

    PubMed  CAS  Google Scholar 

  18. Chipps BE, Valentine MD, Kagey-Sobotka A, et al: Diagnosis and treatment of anaphylactic reactions to Hymenoptera stings in children. J Pediatr 97:177–184, 1980

    Article  PubMed  CAS  Google Scholar 

  19. Graft DF, Schuberth KC, Kagey-Sobotka A, et al: Assessment of prolonged venom immunotherapy in children. J Allergy Clin Immunol 71:140, 1983

    Article  Google Scholar 

  20. Golden DBK, Langlois J, Valentine MD, et al: Treatment failures with whole-body extract therapy of insect sting allergy. JAMA 246:2460–2463, 1981

    Article  PubMed  CAS  Google Scholar 

  21. Lichtenstein LM, Valentine MD, Sobotka AK: Insect allergy: The state of the art. J Allergy Clin Immunol 64:5–12, 1979

    Article  PubMed  CAS  Google Scholar 

  22. Yunginger JW: The sting-revisited. J Allergy Clin Immunol 64:1–2, 1979

    Article  PubMed  CAS  Google Scholar 

  23. Reisman RE: Stinging insect allergy. J Allergy Clin Immunol 64:3–4, 1979

    Article  PubMed  CAS  Google Scholar 

  24. Kagen SL: Inhalent insect allergy in Levine MI, Lockey RD (eds): Monograph on insect allergy. 2nd edition. Pittsburgh, Dave Lambert Associates, 1986

    Google Scholar 

  25. Golden DBK, Kagey-Sobotka A, Valentine MD, et al: Dose dependence of Hymenoptera venom immunotherapy. J Allergy Clin Immunol 67:370–374, 1981

    Article  PubMed  CAS  Google Scholar 

  26. Golden DBK, Valentine MD, Kagey-Sobotka A, et al: Regimens of Hymenoptera venom immunotherapy. Ann Intern Med 92:620–624, 1980

    PubMed  CAS  Google Scholar 

  27. Yunginger JW, Paull BR, Jones RT, et al: Rush venom immunotherapy program for honeybee sting sensitivity. J Allergy Clin Immunol 63:340–347, 1979

    Article  PubMed  CAS  Google Scholar 

  28. Golden DBK, Kagey-Sobotka A, Valentine, MD, et al: Prolonged maintenance interval in Hymenoptera venom immunotherapy. J Allergy Clin Immunol 67:482–484, 1981

    Article  PubMed  CAS  Google Scholar 

  29. Kern F, Sobotka AK, Valentine MD, et al: Allergy to insect sting. III. Allergenic cross-reactivity among the vespid venoms. J Allergy Clin Immunol 57:554–559, 1976

    Article  PubMed  CAS  Google Scholar 

  30. King TP, Sobotka AK, Lochoumain L, et al: Protein allergens of white-faced hornet, yellow jacket and yellow jacket venoms. Biochemistry 17:5156–5174, 1978

    Article  Google Scholar 

  31. Hoffman, DR: Allergens in Hymenoptera venoms. VI. Cross-reactivity of human IgE antibodies to the three vespid venoms and between vespid and paper wasp venoms. Ann Allergy 46:304–309, 1981

    PubMed  CAS  Google Scholar 

  32. Reisman RE, Mueller UR, Wypych JI, et al: Comparison of the allergenicity and antigenicity of yellow jacket and hornet venoms. J Allergy Clin Immunol 69:268–274, 1982

    Article  PubMed  CAS  Google Scholar 

  33. Reisman RE, Wypych JI, Mueller UR, et al: Comparison of the allergenicity and antigenicity of Polistes venom and other vespid venoms. J Allergy Clin Immunol 70:281–287, 1982

    Article  PubMed  CAS  Google Scholar 

  34. Hoffman DR: Allergens in Hymenoptera venom. XV. The immunologic basis of vespid venom cross-reactivity. J Allergy Clin Immunol 75:611–613, 1985

    Article  PubMed  CAS  Google Scholar 

  35. King TP, Joslyn A, Kochoumian L: Antigenic cross-reactivity of venom proteins from hornets, wasps, and yellow jackets. J Allergy Clin Immunol 75:621–628, 1985

    Article  PubMed  CAS  Google Scholar 

  36. Reisman RE: Stinging insect allergy: Progress and problems. J Allergy Clin Immunol 75:553–555, 1985

    Article  PubMed  CAS  Google Scholar 

  37. Golden DBK, Valentine MD, Kagey-Sobotka A, et al: Cross-reactivity of vespid venoms. J Allergy Clin Immunol 67:57 (Abstract), 1981

    Google Scholar 

  38. Golden DBK: Diagnosis and prevalence of stinging insect allergy. Clin Rev Allergy 2:119–136, 1987

    Google Scholar 

  39. Patterson R, Lieberman P, Irons JS, et al: Immunotherapy, in Middleton E, Reed CE, Ellis EF, (eds): Allergy: Principles and Practice. St. Louis, The C.V. Mosby Co., 1983, pp 1119–1142

    Google Scholar 

  40. Graft DF, Valentine MD: Immunotherapy, in Kaplan AP (ed): Allergy. New York, Churchill Livingstone, 1985, pp 679–692

    Google Scholar 

  41. Golden DBK, Kagey-Sobotka A, Hamilton RG, et al: Human immune response to Hymenoptera venoma. J Allergy Clin Immunol 71:140 (Abstract), 1983

    Article  Google Scholar 

  42. Cooke RA, Barnard JH, Hebald S: Serologic evidence of immunity with co-existing sensitization in a type of human allergy (hay fever). J Exp Med 62:733–750, 1935

    Article  CAS  PubMed  Google Scholar 

  43. Lichtenstein LM, Norman PS, Winkerwerder WL: A single year of immunotherapy for ragweed, hay fever: Immunologic and clinical studies. Ann Intern Med 75:663–671, 1971

    PubMed  CAS  Google Scholar 

  44. Evans R, Pence H, Kaplan H, et al: The effect of immunotherapy on humoral and cellular responses in ragweed hay fever. J Clin Invest 57:1378–1385, 1976

    Article  PubMed  CAS  Google Scholar 

  45. Lessof MH, Sobotka AK, Lichtenstein LM: Effects of passive antibody in bee venom anaphylaxis. Johns Hopkins Med J 142:1–7, 1978

    PubMed  CAS  Google Scholar 

  46. Golden DBK, Meyers DA, Kagey-Sobotka A, et al: Clinical relevance of the venom-specific immunoglobulin G antibody level during immunotherapy. J Allergy din Immunol 69:489–493, 1982

    Article  CAS  Google Scholar 

  47. Schuberth KC, Lichtenstein LM, Kagey-Sobotka A, et al: An epidemiologic study of insect allergy in children. I. Characteristics of the disease. J Pediatr 100:546–551, 1982

    Article  PubMed  CAS  Google Scholar 

  48. Schuberth KC, Lichtenstein LM, Kagey-Sobotka A, et al: Epidemiologic study of insect allergy in children. II. Effect of accidental stings in allergic children. J Pediatr 102:361–365, 1983

    Article  PubMed  CAS  Google Scholar 

  49. National Center for Health Statistics. Deaths from each cause by 5-year age groups, race, and sex: United States, 1979–1983. Hyattsville MD

  50. Schuberth KC, Graft DF, Kagey-Sobotka A, et al: Do all children with insect allergy need venom therapy? J Allergy Clin Immunol 71:140 (Abstract), 1983

    Article  Google Scholar 

  51. Graft DF, Schuberth KC, Kagey-Sobotka A, et al: A prospective study of the natural history of large local reactions after Hymenoptera stings in children. J Pediatr 104:664–668, 1984

    Article  PubMed  CAS  Google Scholar 

  52. Mauriello PM, Barde SH, Georgitis JW, et al: Natural history of large local reactions from stinging insects. J Allergy Clin Immunol 74:494–498, 1984

    Article  PubMed  CAS  Google Scholar 

  53. Golden DBK, Valentine MD, Kagey-Sobotka A, et al: Prevalence of Hymenoptera venom allergy. J Allergy Clin Immunol 69:124 (Abstract), 1982

    Article  Google Scholar 

  54. Lichtenstein LM, Kagey-Sobotka A, Golden DBK, et al: Once stung, twice shy: When should insect allergy be treated? JAMA 244:1683–1684 (Commentary), 1980

    Article  PubMed  CAS  Google Scholar 

  55. Mickalide AD, Valentine MD, Dear MR, et al: Insect allergy in children: What is the real cost of the disease? Int Arch Allergy Appl Immunol 77:206–209, 1985

    PubMed  CAS  Google Scholar 

  56. Levine MI: Systemic reactions to immunotherapy. J Allergy Clin Immunol 63:209, 1979

    Google Scholar 

  57. Golden DBK: Insect sting allergy in adults, in Lichtenstein LM, Fauci AS (eds): Current Therapy in Allergy and Immunology 1983–1984. Philadelphia, B.C. Decker Inc., 1983, pp 70–75

    Google Scholar 

  58. Yunginger JW, Jones RT, Leiferman KM: Immunological studies in beekeepers and their family members. J Allergy Clin Immunol 61:93–101, 1978

    Article  PubMed  CAS  Google Scholar 

  59. McDonald JA, Li FP, Mehta CR: Cancer mortality among beekeepers. J Occup Med 21:811–813, 1979

    PubMed  CAS  Google Scholar 

  60. Schwartz HJ, Golden DBK, Lockey RF: Committee on Insects AAAI: Venom immunotherapy (VIT) and the pregnant woman with Hymenoptera allergy (H.A.). J Allergy Clin Immunol 77:140 (Abstract), 1986

    Google Scholar 

  61. Graft DF, Schuberth KC, Kagey-Sobotka A, et al: The development of negative skin tests in children treated with venom immunotherapy. J Allergy Clin Immunol 73:61–68, 1984

    Article  PubMed  CAS  Google Scholar 

  62. Randolph CC, Reisman RE: Further evaluation of decline in venom-specific IgE as a criterion for discontinuing venom immunotherapy (VIT). J Allergy Clin Immunol 75:151 (Abstract), 1985

    Article  Google Scholar 

  63. Urbanek R, Forster J, Kuhn W, et al: Discontinuation of bee venom immunotherapy in children and adolescents. J Pediatr 107:367–371, 1985

    Article  PubMed  CAS  Google Scholar 

  64. Schuberth KC, Kwiterovich KA, Szklo M, et al: Sequelae of accidental stings in children who stop venom immunotherapy. J Allergy Clin Immunol 77:179 (Abstract), 1986

    Google Scholar 

  65. Golden DBK, Kagey-Sobotka A, Gadde J, et al: Is venom immunotherapy (VIT) forever? J Allergy Clin Immunol 75:208, 1985

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Graft, D.F. Venom immunotherapy for stinging insect allergy. Clin Rev Allergy 5, 149–159 (1987). https://doi.org/10.1007/BF02991204

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02991204

Keywords

Navigation