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Drug allergy: An overview

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References

  1. Steel K, Gertman PM, Crescenzi C, Anderson J: Iatrogenic illness on a general medical service at a university hospital. N Engl J Med 304:638, 1981

    PubMed  CAS  Google Scholar 

  2. Jick H: Adverse drug reactions: The magnitude of the problem. J Allergy Clin Immunol 74(part 2):555, 1984

    Article  PubMed  CAS  Google Scholar 

  3. Armstrong B, Dinan B, Jick H: Fatal drug reactions in patients admitted to surgical services. Am J Surg 132:643, 1976

    Article  PubMed  CAS  Google Scholar 

  4. Porter J, Jick H: Drug-related deaths among medical inpatients. JAMA 237:879, 1977

    Article  PubMed  CAS  Google Scholar 

  5. Jick, H: Drugs-Remarkably nontoxic. N Engl J Med 291:284, 1974

    Google Scholar 

  6. Karch FE: Commentary on adverse drug reactors-A matter of opinion. Clin Pharmacol Ther 19:489, 1976

    PubMed  CAS  Google Scholar 

  7. Schindel L: Placebo-induced adverse reactions. In Meyler L, Peck HM (eds): Drug-Induced Diseases, vol 3. Amsterdam, Excerpta Medica, 1968

    Google Scholar 

  8. Kramer MS, Leventhal JM, Hutchinson TA, Feinstein AR: An algorithm for the operational assessment of adverse drug reactions. 1. Background, description, and instructions for use. JAMA 242:623, 1979

    Article  PubMed  CAS  Google Scholar 

  9. Borda IT, Slone D, Jick H: Assessment of adverse reactions within a drug surveillance program. JAMA 205:645, 1968

    Article  PubMed  CAS  Google Scholar 

  10. Boston Collaborative Drug Surveillance Program: Drug-induced anaphylaxis: A cooperative study. JAMA 224:613, 1973

    Google Scholar 

  11. DeSwarte RD: Drug allergy-Problems and strategies. J Allergy Clin Immunol 74:209, 1984

    Article  PubMed  CAS  Google Scholar 

  12. Schatz M, Patterson R, DeSwarte RD: Non-organic adverse reactions to aeroallergen immunotherapy. J Allergy Clin Immunol 58:198, 1976

    Article  PubMed  CAS  Google Scholar 

  13. Wolf S: The pharmacology of placebos. Pharmacol Rev 11:689, 1959

    PubMed  CAS  Google Scholar 

  14. Bartlett JG: Antibiotic-associated pseudomembranous colitis due to toxin-producing Clostridia. N Engl J Med 298:531, 1978

    PubMed  CAS  Google Scholar 

  15. Gelfand JA, Elin RJ, Berry FW Jr, et al: Endotoxemia associated with the Jarisch-Herxheimer reaction. N Engl J Med 295:211, 1976

    PubMed  CAS  Google Scholar 

  16. Martin EW: Hazards of Medication, 2nd ed. Philadelphia, JB Lippincott, 1978

    Google Scholar 

  17. Hansten PD: Drug Interactions, 5th ed. Philadelphia, Lea and Febiger. 1985

    Google Scholar 

  18. Ladu BM: Pharmacogenetics. Med Cli North Am 53:839, 1969

    Google Scholar 

  19. Landsteiner K: The Specificity of Serological Reactions. Cambridge, Harvard University Press, 1945

    Google Scholar 

  20. Levine BB: Immunologic mechanisms of penicillin allergy. A haptenic model system for the study of allergic diseases in man. N Engl J Med 275:1115, 1966

    PubMed  CAS  Google Scholar 

  21. Bundgaard H, DeWeck AL: The role of amino-reactive impurities in acetylsalicylic acid. Int Arch Allergy AppI Immunol 49:119, 1978

    Google Scholar 

  22. Rosenberg S, Landay R, Klotz SD, Fireman P: Serum IgE antibodies to psyllium in individuals allergic to psyllium and English plantain. Ann Allergy 48:294, 1982

    PubMed  CAS  Google Scholar 

  23. Twarog FG: Hypersensitivity to pancreatic extracts in parents of patients with cystic fibrosis. J Allergy Clin Immunol 59:35, 1977

    Article  PubMed  CAS  Google Scholar 

  24. Petz LD, Fudenberg HH: Immunologic mechanisms in drug-induced cytopenias. In Brown EB (ed): Progress in Hematology, vol 9. New York, Grune and Stratton, 1975

    Google Scholar 

  25. Dukor P, Kallos P, Schlumberger HD, West GB: Pseudo-allergic reactions, vol 1. Genetic aspects and anaphylactoid reactions. Basel, S. Karger, 1980

    Google Scholar 

  26. Reidenberg MM, Lowenthal D: Adverse nondrug reactions. N Engl J Med 279:678, 1968

    PubMed  CAS  Google Scholar 

  27. DeSwarte RD: Drug allergy. In Patterson R (ed): Allergic Diseases: diagnosis and management, ed 3. Philadelphia, JB Lippincott Co, 1985

    Google Scholar 

  28. Cluff LE, Caranasos GJ, Stewart RB: Clinical problems with drugs. Philadelphia, WB Saunders Co, 1975

    Google Scholar 

  29. Davies DM (ed): Textbook of adverse drug reactions. Oxford, Oxford University Press, 1981

    Google Scholar 

  30. Meyler L, Herxheimer A (eds): Side effects of drugs, vols I to VII. Amsterdam, Excerpta Medica, 1955 to 1972

    Google Scholar 

  31. Dukes mng (ed): Side effects of drugs, vols viii and ix. Amsterdam, Excerpta Medica, 1975 and 1980

    Google Scholar 

  32. Dukes MNG (ed): Side effects of drugs, annual 1 to 8. Amsterdam-Oxford, Excerpta Medica, 1973 to 1984.

    Google Scholar 

  33. Weiss RB: Hypersensitivity reactions to cancer chemotherapy. Semin Oncol 9:5, 1982

    PubMed  CAS  Google Scholar 

  34. Stoelting RK: Allergic reactions during anesthesia. Anesth Anal 62:341, 1983

    Article  CAS  Google Scholar 

  35. Mendelson LM, Meltzer EO, Hamburger RN: Anaphylaxis-like rections to corticosteroid therapy. J Allergy Clin Immunol 54:125, 1974

    Article  PubMed  CAS  Google Scholar 

  36. Knapp AB, Grimshaw RS Jr, Goldfarb JP, et al: Cimetadine-induced anaphylaxis. Ann Intern Med 97:374, 1982

    PubMed  CAS  Google Scholar 

  37. Barnett EV, Stone G, Swisher SN, et al: Serum sickness and plasmacytosis: Clinical, immunologic, and hematologic analysis. Am J Med 35:113, 1963

    Article  PubMed  CAS  Google Scholar 

  38. Benveniste J, Henson PM, Cochrane CG: A possible role for IgE in immune complex disease. In Ishazaka K, Dayton DH Jr. (eds): The biologic role of the IgE system. Bethesda, US Dept of HEW, 1973

    Google Scholar 

  39. Kniker WT, Guerra FA, Richards SEM: Prevention of immune complex disease (serum sickness) by antagonists of vasoactive amines. Pediat Res 5:381, 1971

    Google Scholar 

  40. DeBard ML: Methyldopa reaction simulating septic shock. Arch Intern Med 139:196, 1979

    Article  PubMed  CAS  Google Scholar 

  41. Chusid MJ, Atkins E: Studies on the mechanism of penicillin-induced fever. J Exp Med 136:227, 1972

    Article  PubMed  CAS  Google Scholar 

  42. Bernheim HA, Block LH, Atkins E: Fever: pathogenesis, pathophysiology, and purpose. Ann Intern Med 91:261, 1979

    PubMed  CAS  Google Scholar 

  43. Utsinger PD, Zvailfler NJ, Bluestein HG: Hypocomplementemia in procainamide-associated systemic lupus erythematosus (letters). Ann Intern Med 84: 293, 1976

    PubMed  CAS  Google Scholar 

  44. Blomgren SE, Condemi JJ, Bignall NC et al: Antinuclear antibody induced by procainamide. A prospective study. N Engl J Med 281:64, 1969

    PubMed  CAS  Google Scholar 

  45. Fritzler MJ, Tan EM: Antibodies to histones in drug-induced and idiopathic lupus erythematosus. J Clin Invest 62:560, 1978

    Article  PubMed  CAS  Google Scholar 

  46. Becker M, Klajman J, Moalem T, et al: Circulating immune complexes in sera from patients receiving procainamide. Clin Immunol Immunopathol 12:220, 1979

    Article  PubMed  CAS  Google Scholar 

  47. Atkinson AJ Jr, Lee WK, Quinn ML, et al: Dose-ranging trial of N-acetylprocainamide in patients with premature ventricular contractions. Clin Pharmacol Ther 21:575, 1977

    PubMed  Google Scholar 

  48. Parker CW: Drug allergy. In Parker CW (ed): Clinical Immunology, vol 2. Philadelphia, WB Saunders Co, 1980

    Google Scholar 

  49. Braverman IM, Yen A: Demonstration of immune complexes to spontaneous and histamine-induced lesions and in normal skin of patients with leukocytoclastic angiitis. J Invest Dermatol 64:105, 1975

    Article  PubMed  CAS  Google Scholar 

  50. Arndt KA, Jick H: Rates of cutaneous reactions to drugs: A report from the Boston Collaborative Drug Surveillance Program. JAMA 235:913, 1976

    Article  Google Scholar 

  51. Kuokhanen K: Drug eruptions: A series of 464 cases in the Department of Dermatology, University of Turka, Finland, during 1966–1970. Acta Allergol 27:407, 1972

    Google Scholar 

  52. Dunagen WG, Millikan LE: Drug eruptions. Med Clin North Am 64:983, 1980

    Google Scholar 

  53. Fisher AA: Topical medicaments which are common sensitizers. Ann Allergy 49:97, 1982

    Google Scholar 

  54. Elias J, Hevinson A: Hypersensitivity reactions to ethylenediamine in aminophylline. Am Rev Resp Dis 123:550, 1981

    PubMed  CAS  Google Scholar 

  55. Kazmierowski JA, Wuepper KD: Erythema multiforme: Immune complex vasculitis of the superficial cutaneous microvasculature. J Invest Dermatol 71:366, 1978

    Article  PubMed  CAS  Google Scholar 

  56. Hasan T, Jansen CT: Erythroderma: A follow-up study of fifty cases. J Am Acad Dermatol 8: 836, 1983

    Article  PubMed  CAS  Google Scholar 

  57. Amon RB, Dimond RL: Toxic epidermal necrolysis: rapid differentiation between staphy-lococcal-induced disease and drug-induced disease. Arch Dermatol 111:1433, 1975

    Article  PubMed  CAS  Google Scholar 

  58. Rosenow EC III: Drug-induced hypersensitivity in the lung. In Kirkpatrick CH, Reynolds HY (eds): Immunologic and infectious reactions in the lung. New York, Marcel Dekker, 1977

    Google Scholar 

  59. Rosenow EC III: Miscellaneous drug-induced pulmonary disease. Semin Resp Med 2:76, 1980

    Article  Google Scholar 

  60. Weber RW, Hoffman M, Raine DA et al: Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes and preservatives in a population of perennial asthmatics. J Allergy Clin Immunol 64:32, 1979

    Article  PubMed  CAS  Google Scholar 

  61. Stevenson DD: Diagnosis, prevention, and treatment of adverse reactions to aspirin (ASA) and nonsteroidal anti-inflammatory drugs (MSAID). J Allergy Clin Immunol 74:617, 1984

    Article  PubMed  CAS  Google Scholar 

  62. Pleslow WW, Stevenson DD, Mathison DA et al: Aspirin-sensitive rhinosinusitis/asthma: Spectrum of adverse reactions to aspirin. J Allergy Clin Immunol 71:574, 1983

    Article  Google Scholar 

  63. Goetzl EJ: Mediators of immediate hypersensitivity derived from arachidonic acid. N Engl J Med 303:822, 1980

    PubMed  CAS  Google Scholar 

  64. Dajani BM, Silman NA, Shubair KS et al: Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics. J Allergy Clin Immunol 68:201, 1981

    Article  PubMed  CAS  Google Scholar 

  65. Settipane GA: Metabisulfites in drugs. N Engl Reg Allergy Proc 4:304, 1983

    Article  Google Scholar 

  66. Holmberg L, Bowman G, Bottinger LE, et al: Adverse reactions to nitrofurantoin. Analysis of 921 reports. Am J Med 69:733, 1980

    Article  PubMed  CAS  Google Scholar 

  67. Back O, Liden S, Ahlstedt S: Adverse reactions to nitrofurantoin in relation to cellular and humoral immune response. Clin Exp Immunol 28:400, 1976

    Google Scholar 

  68. Herman JJ: Intractable sneezing due to IgE-mediated triethandamine sensitivity. J Allergy Clin Immunol 71:339, 1983

    Article  PubMed  CAS  Google Scholar 

  69. Spry CJF: Eosinophilia and allergic reactions to drugs. Clin Haematol 9:521, 1980

    PubMed  CAS  Google Scholar 

  70. Mitchell JR, Zimmerman HJ, Ishak KG et al: Isoniazid liver injury: Clinical spectrum, pathology, and probable pathogenesis. Ann Intern Med 84:181, 1976

    PubMed  CAS  Google Scholar 

  71. Mills PR, Rüssel RI: Diagnosis of hepatic granulomas: A review. J Royal Soc Med 76:393, 1983

    CAS  Google Scholar 

  72. Appel GB, Dagati V, Bergman M, Pirani CL: Nephrotic syndrome and immune complex glomerulonephritis associated with chlorpropamide therapy. Ann J Med 74:337, 1983

    CAS  Google Scholar 

  73. Kleinknecht D, Vanhille Ph, Morel-Maroger L, et ai: Acute interstitial nephritis due to drug hypersensitivity. An up-to-date review with a report of 19 cases. Adv Nephrol 12:277, 1983

    CAS  Google Scholar 

  74. Brezin JH, Katz SM, Schwartz AB, et al: Reversible renal failure and nephrotic syndrome associated with nonsteroidal anti-inflammatory drugs. N Engl J Med 301:1271, 1979

    PubMed  CAS  Google Scholar 

  75. Border WZ, Lehman DH, Egan JD, et al: Antitubular basement membrane antibodies in methicillin-associated interstitial nephritis. N Engl J Med 291:381, 1974

    Article  Google Scholar 

  76. Husby G, Tung KSK, Williams RC Jr: Characteristization of renal tissue lymphocytes in patients with interstitial nephritis. Am J Med 70:31, 1981

    Article  PubMed  CAS  Google Scholar 

  77. Frizzera G, Moran EM, Rappaport H: Angioimmunoblastic lymphadenopathy with dys-proteinemia. Lancet i:1070, 1974

    Article  Google Scholar 

  78. Tomecki KH, Catalano CJ: Dapsone hypersensitivity. Arch Dermatol 117: 38, 1981

    Article  PubMed  CAS  Google Scholar 

  79. Jarisch R, Roth A, Boltz A, et al: Diagnosis of penicillin allergy by means of Phadebas RAST penicilloyl G and V skin tests. Clin Allergy 11:155, 1981

    Article  PubMed  CAS  Google Scholar 

  80. Kraft D, Berglund A, Rumpold H, et al: Radioallergosorbent test with conjugates specific for “minor” heptenic determinants in the diagnosis of IgE-mediated penicillin allergy in man. Clin Allergy 11:579, 1981

    Article  PubMed  CAS  Google Scholar 

  81. Bretza J, Wells I, Novey HS: Association of IgE antibodies to sodium aurothiomalate and adverse reactions to chrysotherapy for rheumatoid arthritis. Am J Med 74:945, 1983

    Article  PubMed  CAS  Google Scholar 

  82. Grammar LC, Patterson R: Proteins: Chymopapain and insulin. J Allergy Clin Immunol 74:635, 1984

    Article  Google Scholar 

  83. Rocklin RE: Clinical application of in vitro lymphocyte tests. In Schwartz RS (ed): Progress in clinical immunology, vol 2. New York, Grune & Stratton Inc, 1974

    Google Scholar 

  84. Rosenthal A: Follow-up study of fatal penicillin reactions. JAMA 167:1118, 1958

    CAS  Google Scholar 

  85. Lawson DH, Jick H: Drug prescribing in hospitals: an international comparison. Am J Public Health 66: 644, 1976

    Article  PubMed  CAS  Google Scholar 

  86. Mathews KP: Clinical spectrum of allergic and pseudo allergic drug reactions. J Allergy Clin Immunol 74 (part 2): 558, 1984

    Article  PubMed  CAS  Google Scholar 

  87. Delafuente JC: Is it really a drug allergy? Hosp Formul 20:355, 1985

    Google Scholar 

  88. Baigelman W, Cupples LA, Harding J, Vignoni B: Documentation of drug allergy in CCU patients. Hosp Pract 90:6, 1983

    Google Scholar 

  89. Norman PS: Adverse drug reactions and alternative drugs of choice. In Modell W (ed): Drugs of choice 1982–83. St. Louis, The CV Mosby Co, 1982

    Google Scholar 

  90. Adkinson NF Jr: Risk factors for drug allergy. J Allergy Immunol 74 (part 2):567, 1984

    Article  Google Scholar 

  91. Miller JR, Orgel A, Meltzer EO: The safety of egg-containing vaccines for egg-allergic patients. J Allergy Clin Immunol 71:568, 1983

    Article  PubMed  CAS  Google Scholar 

  92. Mendelson LM, Ressler C, Rosen JP, et al: Routine elective penicillin allergy skin testing in children and adolescents: Study of sensitization. J Allergy Clin Immunol 73:76, 1984

    Article  PubMed  CAS  Google Scholar 

  93. Lieberman P, Patterson R, Metz R, Lucena G: Allergic reactions to insulin. JAMA 215:1106, 1971

    Article  PubMed  CAS  Google Scholar 

  94. Ross AC, Knapp DE: Discovery of new adverse drug reactions. A review of the Food and Drug Administration’s Spontaneous Reporting System. JAMA 252:1030, 1984

    Article  Google Scholar 

  95. Wingert WA, Wainschel J: Diagnosis and management of evenomation by poisonous snakes. South Med J 68:1015, 1975

    PubMed  CAS  Google Scholar 

  96. Herman JJ, Radin R, Schneiderman R: Allergic reactions to measles (rubeola) vaccine in patients hypersensitive to egg protein. J Pediat 102:196, 1983

    Article  PubMed  CAS  Google Scholar 

  97. Stevenson DD: Desensitization of aspirin-sensitive asthmatics: A therapeutic alternative. J Asthma 20:31, 1983

    Article  PubMed  Google Scholar 

  98. Stevenson DD, Pleskow WW, Simon RA et al: Aspirin sensitive rhinosinusitis asthma: A double-blind crossover study of treatment with aspirin. J Allergy Clin Immunol 73:500, 1984

    Article  PubMed  CAS  Google Scholar 

  99. Purdy BH, Philips DM, Summers RW: Desensitization of sulfasalazine skin rash. Ann Intern Med 100:512, 1984

    PubMed  CAS  Google Scholar 

  100. Thompson JE: The management of hypersensitivity reactions to antitubuculous drugs. Med J Aust 36:1058, 1969

    Google Scholar 

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  1. Northwestern University Medical School, 60611, Chicago, IL

    Richard D. DeSwarte MD (Clinical Associate Professor of Medicine)

  2. the Rockford Clinic, Ltd., Rockford, IL

    Richard D. DeSwarte MD (Clinical Associate Professor of Medicine)

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DeSwarte, R.D. Drug allergy: An overview. Clin Rev Allergy 4, 143–169 (1986). https://doi.org/10.1007/BF02991106

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