Skip to main content
Log in

Measurements of blood viscosity using a pressure-scanning slit viscometer

  • Published:
KSME International Journal Aims and scope Submit manuscript

Abstract

A newly designed pressure-scanning slit viscometer is developed to combine an optical device without refraction while measuring blood viscosity over a range of shear rates. The capillary tube in a previously designed capillary viscometer was replaced with a transparent slit, which is affordable to mount optical measurement of flowing blood cells. Using a pressure transducer, we measured the change of pressure in a collecting chamber with respect to the time, p(t), from which the viscosity and shear rate were mathematically calculated. For water, standard oil and whole blood, excellent agreement was found between the results from the pressure-scanning slit viscometer and those from a commercially available rotating viscometer. This new viscometer overcomes the drawbacks of the previously designed capillary viscometer in the measuring whole blood viscosity. First, the pressure-scanning slit viscometer can combine an optical instrument such as a microscope. Second, this design is low cost and simple (i.e., ease of operation, no moving parts, and disposable).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Abbreviations

h:

Half slit gap (mm)

L:

Slit length (m)

P:

Pressure (Pa)

Q:

Flow rate (m3/s)

t:

Time (s)

V:

Volume (m3)

v:

Voltage (V)

w:

Slit width (mm)

ρ:

Density (kg/m3)

\(\dot \gamma \) :

Shear rate (s-1)

η:

Non-Newtonian viscosity (Pa·s)

τ:

Shear stress (Pa)

A:

Atmospheric condition

h:

Head

i:

Initial

w:

Wall

References

  • Bird, R., Amstrong, R. C. and Hassager, O., 1987,Dynamics of Polymeric Liquids, Vol. 1, New York: John Wiley & Son.

    Google Scholar 

  • Chandler, W. L. and Schmer, G., 1986, “Evaulation of a New Dynamic Viscometer for Measuring the Viscosity of Whole Blood and Plasma, ”Clin. Chem., Vol. 32, pp. 505–507.

    Article  Google Scholar 

  • Dintenfass, L., 1969, “ Blood Rheology in Pathogenesis of the Coronary Heart Deseases, ” Am. Heart J. Vol. 77, pp. 139–147.

    Article  Google Scholar 

  • Fahraeus, R. and Lindquist, T., 1931, The Viscosity of the Blood in Narrow Capillary Tubes,Am. J. Physio., Vol. 96, No. 562, pp. 1931–1939.

    Google Scholar 

  • Fossum, E., Høieggen, A. and Moan, A., 1997, “ Whole Blood Viscosity, Blood Pressure and Cardiovascular Risk Factors in Healthy Blood Donors, ”Blood Press., Vol. 6, pp. 161–165.

    Article  Google Scholar 

  • Kim, S., Cho, Y. I., Kensey, K. R., Pellizzari, R. O. and Stark, P. R. H., 2000, “ A Scanning Dual-Capillary-Tube Viscometer, ”Review of Scientific Instruments, Vol. 71, pp. 3188–3192.

    Article  Google Scholar 

  • Lide, D. R.(Ed), 1994, CRC handbook of chemistry and physics, 75th ed.CRC Press, Boca Raton, FL.

    Google Scholar 

  • Macosko, W., 1993,Rheology: Principles, Measurements, and Applications, VCH, New York.

    Google Scholar 

  • Ogawa, K., Okawara, S., Ito, S. and Taniguchi, K., 1991, “ Blood Viscometer with Vacuum Glass Suction Tube and Needle, ”J. Chemical Eng. of Japan, Vol.24, p. 215–221.

    Article  Google Scholar 

  • Reinhart, W. H., Haeberli A., Stark, J. and Straub, P. W., 1990, “ Influence of Blood Withdrawal and Anticoagulant on Clotting Activity, Hematologic Data, and Certain Rheologic Measurements, ”J. Lab. Clinical Med., Vol. 115, pp. 98–103.

    Google Scholar 

  • Shin, S. and Keum, D. Y., 2002a, “ Continuous Viscosity Measurement of Polymer Solutions over a Range of Shear Rates Using a Mass-Detecting Capillary Viscometer, ”KSME Int. J., Vol. 16, pp. 255–261.

    Article  Google Scholar 

  • Shin, S. and Keum, D. Y., 2002b, “ A New Mass-Detecting Capillary Viscometer, ”Biosensor and Bioelectronics, Vol. 17, pp. 383–388.

    Article  Google Scholar 

  • Shin, S., Keum, D. Y. and Ku, Y. H., 2002c, “Blood Viscosity Measurement Using a Pressure-Scanning Capillary Viscometer, ”KSME Int. J., Vol. 16, pp. 1719–1724.

    Article  Google Scholar 

  • Singh, M. and Coulter, A., 1973, “ Rheology of Blood Effect of Dilution with Various Dextrans, ”Microvasc. Res., Vol. 5, pp. 123–135.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sehyun Shin.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shin, S., Lee, SW. & Ku, YH. Measurements of blood viscosity using a pressure-scanning slit viscometer. KSME International Journal 18, 1036–1041 (2004). https://doi.org/10.1007/BF02990876

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02990876

Key Words

Navigation