Abstract
The movement of copper and zinc from the fertilized egg into the developing embryo and the subsequent association of the two metals with metallothionein-like proteins (MT) of chick liver was investigated. Hepatic levels of MT in 1-d-old chicks, estimated from specifically bound115mCd, were increased eightfold over endogenous levels of these copper- and zinc-binding proteins in adult liver. Copper was assimilated from the oocyte into the embryo more rapidly than zinc in the early stages of embryogenesis. Between 15 and 16 d of development, during the time that (MT) was detected, there was a significant increase in copper concentration, whereas hepatic zinc concentration remained relatively constant.
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Sandrock, B.C., Kern, S.R. & Bryan, S.E. The movement of zinc and copper from the fertilized egg into metallothionein-like proteins in developing chick hepatic tissue. Biol Trace Elem Res 5, 503–515 (1983). https://doi.org/10.1007/BF02988942
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DOI: https://doi.org/10.1007/BF02988942