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The incorporation of selenium and alterations of macro- and trace element levels in individual blood cells following supplementation with sodium selenite and vitamin E

A nuclear microprobe application

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Abstract

Significant alterations in the selenium content of erythrocytes, thrombocytes, and neutrophil granulocytes were observed following a daily supplementation of 200 μg Se + 100 mg vitamin E during a period of 2 months. The neutrophil granulocytes incorporated more selenium than the thrombocytes. The iron content of the thrombocytes decreased on selenium supplementation, while the opposite was noted for the neutrophil granulocytes. The glutathione peroxidase activity was not significantly changed during the period of observation.

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Authors and Affiliations

  1. Gustaf Werner Institute, Uppsala University, Uppsala, Sweden

    Erland Johansson & Ulf Lindh

  2. Department of Physical Biology, Uppsala, Sweden

    Erland Johansson & Ulf Lindh

  3. Department of Biomedical Research, Pharmacia AB, Uppsala, Sweden

    EBBA LANDSTRöM

Authors
  1. Erland Johansson
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  2. Ulf Lindh
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  3. EBBA LANDSTRöM
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Johansson, E., Lindh, U. & LANDSTRöM, E. The incorporation of selenium and alterations of macro- and trace element levels in individual blood cells following supplementation with sodium selenite and vitamin E. Biol Trace Elem Res 5, 433–447 (1983). https://doi.org/10.1007/BF02988937

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  • DOI: https://doi.org/10.1007/BF02988937

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