Skip to main content
Log in

A patient with two thyroid papillary carcinomas demonstrating hot and cold lesions on 123I thyroid scintigraphy

  • Case Reports
  • Published:
Annals of Nuclear Medicine Aims and scope Submit manuscript

Abstract

A 44-year-old euthyroid woman had two palpable nodules in the thyroid gland. 123I thyroid scintigraphy showed a hot nodule in the right lobe and a cold one in the left lobe. Total thyroidectomy was performed, and histopathologic examination revealed that both tumors contained papillary carcinoma. Thus, hot nodules on a thyroid scintigram with 123I do not necessarily preclude malignancy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Ashcraft MW, Van Herle AJ. Management of thyroid nodules. I. Head and Neck Surgery 1981; 3: 297–322.

    Article  PubMed  CAS  Google Scholar 

  2. Ikekubo K, Hino M, Ito H, Otani M, Yamaguchi H, Saiki Y, et al. Thyroid carcinoma in solitary hot lesions on Tc-99m sodium pertechnetate scans. Ann Nucl Med 1989; 3: 31–36.

    PubMed  CAS  Google Scholar 

  3. Hay ID, Morris JC. Toxic adenoma and toxic multinodular goiter. In. The Thyroid, seventh edition, Braverman EL, Utiger DR, eds. Philadelphia; Lippincott-Raven Publishers, 1996: 566–572.

    Google Scholar 

  4. Ghose MK, Genuth SM, Abellera RM, Friedman S, Lidsky I. Functioning primary thyroid carcinoma and metastases producing hyperthyroidism. J Clin Endocr 1971; 33: 639–646.

    Google Scholar 

  5. Katagiri M, Suzuki S, Sadahiro S, Kubouchi K, Ohmura T, Tsumura O, et al. Accumulation of iodine-131 and technetium-99m pertechnetate in thyroid carcinoma. Eur J Nucl Med 1988; 13: 276–279.

    CAS  Google Scholar 

  6. Sandler MP, Fellmeth B, Salhany KE, Patton JA. Thyroid carcinoma masquerading as a solitary benign hyperfunctioning nodule. Clin Nucl Med 1988; 13: 410–415.

    Article  PubMed  CAS  Google Scholar 

  7. Rosa GD, Testa A, Maurizi M, Satta MA, Aimoni C, Artuso A, et al. Thyroid carcinoma mimicking a toxic adenoma. Eur J Nucl Med 1990; 17: 179–184.

    Article  PubMed  Google Scholar 

  8. Michigishi T, Mizukami Y, Shuke N, Satake R, Noguchi M, Aburano T, et al. An autonomously functioning thyroid carcinoma associated with euthyroid Graves' disease. J Nucl Med 1992; 33: 2024–2026.

    PubMed  CAS  Google Scholar 

  9. Cirillo RL, Pozderac RV, Caniano DA, Falko JM. Metastatic pure papillary thyroid carcinoma presenting as a toxic hot nodule. Clin Nucl Med 1998; 23: 345–349.

    Article  PubMed  Google Scholar 

  10. Elizabeth D, Rosen BI, Jerald B, Jaccqueline J, Kirsh CJ. Management of the hot thyroid nodule. Am J Surg 1995; 170: 481–483.

    Article  Google Scholar 

  11. Khan O, Ell PJ, Maclennan KA, Kurtz A, Williams ES. Thyroid carcinoma in an autonomously hyperfunctioning thyroid nodule. Postgrad Med J 1981; 57: 172–175.

    Article  PubMed  CAS  Google Scholar 

  12. Hoving J, Piers DA, Vermey A, Oosterhuis JW. Carcinoma in hyperfunctioning thyroid nodule in recurrent hyperthyroidism. Eur J Nucl Med 1981; 6: 131–132.

    Article  PubMed  CAS  Google Scholar 

  13. Livadas DP, Kotoulas OB, Bouropoulou V, Sfontouris J, Psarras A, Koutras DA. The coexistence of thyroid malignancy with autonomous hot nodules of the thyroid. Clin Nucl Med 1977; 2: 350–354.

    Article  Google Scholar 

  14. Kusić Z, Becker DV, Saenger EL, Paras P, Gatside P, Wessler T, et al. Comparison of technetium-99m and iodine-123 imaging of thyroid nodules: correlation with pathologic findings. J Nucl Med 1990; 31: 393–399.

    PubMed  Google Scholar 

  15. Liel T, Ariad S, Barchana M. Long-term follow-up of patients with initially benign thyroid fine-needle aspirations. Thyroid 2001; 11: 775–778.

    Article  PubMed  CAS  Google Scholar 

  16. Ochi H, Sawa H, Fukuda T, Inoue Y, Nakajima H, Masuda Y, et al. Thallium-201-chloride thyroid scintigraphy to evaluate benign and/or malignant nodules. Cancer 1982; 50: 236–240.

    Article  PubMed  CAS  Google Scholar 

  17. Koizumi M, Taguchi H, Goto M, Nomura T, Watari T. Thallium-201 scintigraphy in the evaluation of thyroid nodules—A retrospective study of 246 cases. Ann Nucl Med 1993; 7: 147–152.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Masahiro Iwata.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Iwata, M., Kasagi, K., Misaki, T. et al. A patient with two thyroid papillary carcinomas demonstrating hot and cold lesions on 123I thyroid scintigraphy. Ann Nucl Med 16, 355–358 (2002). https://doi.org/10.1007/BF02988621

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02988621

Key words

Navigation