Abstract
Simultaneous presentation of chronic lymphocytic leukemia and polycythemia vera is reported in a previously untreated patient. The course was remarkably mild with almost no treatment, suggesting control of each disease by the other.
The association of polycythemia vera (PV) and lymphoid neoplasms in the same patient is very unusual in the absence of previous cytotoxic therapy. Six cases of PV and chronic lymphocytic leukemia (CLL) have been reported, in which the occurrence of the two disorders was simultaneous, or sequential but spontaneous. We describe an additional patient in whom the presence of the two malignancies was clearly established, and who needed almost no therapy for more than 3 yr.
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Bethard W F, Block M H, Robson M: Coexistent chronic lymphatic leukemia and polycythemia vera.Blood 8, 934 (1953).
Heinle E W, Sarasti H O, Garcia D, Kenny J J, Westerman M P: Polycythemia vera associated with lymphomatous disease and myeloma.Arch intern Med 118, 351 (1966).
Vianna N J, Essman L J: Suppression of chronic lymphocytic leukemia by polycythemia vera.Cancer 27, 1337 (1971).
Taberner D A, Otridge B W, Chang J: Coexistent chronic lymphatic leukaemia with polycythaemia vera.Postgrad Med J 53, 222 (1977).
Januszewicz E, Firkin F C: Dual presentation of polycythaemia vera and lymphatic leukaemia.Aust NZ J Med 10, 209 (1980).
Manoharan A, Catovsky D, Clein P, Traub N E, Costello C, O’Brien M, Boralessa H, Galton D A G: Simultaneous or spontaneous occurrence of lympho- and myeloproliferative disorders: a report of four cases.Br J Haemat 48, 111 (1981).
Burkhardt R, Frish B, Bartl R: Bone marrow biopsy in haematological disorders.J clin Path 35, 257 (1982).
Berlin N I: Diagnosis and classification of the polycythemias.Sem Hemat 12, 339 (1975).
Binet J L, Catovsky D, Chandra P, Dighiero G, Montserrat E, Rai K R, Jawitsky A: Chronic lymphocytic leukaemia: proposals for a revised prognostic staging system.Br J Haemat 48, 365 (1981).
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Botelho de Sousa, A., Gouveia, J. Coexistent chronic lymphocytic leukemia and polycythemia vera requiring no treatment. Med. Oncol. & Tumor Pharmacother. 6, 239–240 (1989). https://doi.org/10.1007/BF02985197
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DOI: https://doi.org/10.1007/BF02985197