Medical Oncology and Tumor Pharmacotherapy

, Volume 6, Issue 4, pp 279–283 | Cite as

Treatment of small cell lung cancer by eight weeks chemotherapy

  • S. M. Crawford
  • D. Parker
  • M. G. Glaser
  • B. M. Southcott
  • R. H. J. Begent
  • G. J. S. Rustin
  • E. S. Newlands
  • A. J. Ward
  • K. D. Bagshawe
Original Articles


Eighty-two patients with small cell lung cancer (SCLC), 32 with limited disease, were treated with alternating chemotherapy. Eight courses were administered at weekly intervals, and responding patients received radiotherapy to sites of bulk disease. Overall response rate was 76.8%. Overall median survival was 265 days, 408 days in patients with limited disease. The median symptom free period after chemotherapy was completed was 123 days. These results are comparable with those in reports of chemotherapy of longer duration and warrant the further investigation of short duration treatment in this disease.

Key words

Small cell lung cancer Alternating chemotherapy 


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Copyright information

© Humana Press Inc. 1989

Authors and Affiliations

  • S. M. Crawford
    • 1
  • D. Parker
    • 3
  • M. G. Glaser
    • 2
  • B. M. Southcott
    • 2
  • R. H. J. Begent
    • 1
  • G. J. S. Rustin
    • 1
  • E. S. Newlands
    • 1
  • A. J. Ward
    • 3
  • K. D. Bagshawe
    • 1
  1. 1.Cancer Research Campaign Laboratories and Department of Medical OncologyCharing Cross HospitalLondon
  2. 2.Department of RadiotherapyCharing Cross HospitalLondon
  3. 3.Department of Clinical OncologyBradford Royal InfirmaryBradfordUK

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