Summary
1. As a result of crossing-over between two differently invertedX-chromosomes anX-chromosome was obtained with a deficiency for a part of its genetically inert region.
2. In theXY males carrying this chromosome, theX andY-chromosomes synapse only in 61·4 per cent. of cases. Each of the unsynapsed chromosomes is lost during disjunction approximately in one-fourth of the cases, not reaching either of the daughter nuclei.
3.XYY males carrying this chromosome produce gametes almost exclusively of theXY andY types.
4. The case studied appears to confirm the views of Muller and Painter concerning the homology of the inert part of theX-chromosome with theY-chromosome, and supports the opinion that few or no gene mutations can at present arise in theY-chromosome (except those of the genebb).
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References
Agol, I. I. (1929). “Step-allelomorphism inDrosophila melanogaster, etc.”Journ. Exp. Biol. (Russian)5, 84–101.
Bridges, C. B. (1916). “Non-disjunction as proof of the chromosome theory of heredity.”Genetics,1, 1–52, 107–63.
Dobzhansky, Th. (1932). “Cytological map of theX-chromosome ofDrosophila melanogaster.”Biol. Zentralbl. 52, 493–509.
Kuhn (1929). “Ein Beweis für die Lebensfähigkeit von Spermatozoen ohneX undY-Chromosomen beiDrosophila melanogaster.”Z. ind. Abst. Vererb. 53, 26–7.
Morgan, T. H.,Bridges, C. B. andSturtevant, A. H. (1925).The Genetics of Drosophila. s’Gravenhage. Pp. 262.
Muller, H. J. andPainter, T. S. (1932). “The differentiation of sex-chromosomes ofDrosophila into genetically active and inert regions,”Z. ind. Abst. Vererb. 62, 316–65.
Painter, T. S. (1931). “A cytological map of theX-chromosome ofDrosophila melanogaster.”Science,73, 647–8.
Painter, T. S. andMuller, H. J. (1932). “A cytological map of theX-chromosome ofDrosophila.”Proc. Sixth Int. Cong. Gen. 1, 147–8.
Sidorov, B. N. (1931). “Investigation of the step-allelomorphism inD. melanogaster, etc.”Journ. Exp. Biol. (Russian)7, 28–40.
Sivertzev-Dobzhansky, N. P. andDobzhansky, Th. (1933). “Deficiency and duplications for the gene bobbed inDrosophila melanogaster.”Genetics,18, 173–92.
Stern, C. (1927). “Ein genetischer und zytologischer Beweis für Vererbung imY-Chromosom vonDrosophila melanogaster.”Z. ind. Abst. Vererb. 44, 188–231.
—— (1929). “Untersuchungen über Aberrationen desY-Chromosom vonDrosophila melanogaster.” Ibid.51, 253–353.
—— (1930). “Über Reduktionstypen der Heterochromosomen vonDrosophila melanogaster.”Biol. Zentralbl. 49, 718–53.
Wilson, E. B. (1907). “Note on the chromosome groups ofMetapodius andBanasa.”Biol. Bull. 12, 303–13.
—— (1909). “Studies on chromosomes. V. The chromosomes ofMetapodius, etc.”Journ. Exp. Zool. 6, 143–215.
—— (1910). “Studies on chromosomes. VI. A new type of chromosome-combination inMetapodius.” Ibid.9, 53–78.
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Gershenson, S. Studies on the genetically inert region of theX-chromosome ofDrosophila . Journ. of Genetics 28, 297–313 (1933). https://doi.org/10.1007/BF02981776
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DOI: https://doi.org/10.1007/BF02981776