Summary
Heterogeneity of recombination tests may result in heterogeneity in the distribution of mutants over a chromosome map. Differential effects of various mutagens on the distribution pattern cannot be regarded as proven unless the localization tests are homogeneous. Differential production of visible mutants cannot be demonstrated by comparing observations made by different workers.
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References
Fahmy, O. G. &Fahmy, Myrtle J. (1956). Cytogenetic analysis of the action of carcinogens and tumour inhibitors inDrosophila melanogaster. V. Differential genetic response to the alkylating mutagens and X-radiation.J. Genet. 54, 146–64.
Spencer, W. P. &Stern, C. (1948). Experiments to test the validity of the linearr-dose/mutation frequency relation in Drosophila at low dosage.Genetics,33, 43–74.
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Stern, C. A note on the detection of differential effects of mutagens. J Genet 55, 276–279 (1957). https://doi.org/10.1007/BF02981643
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DOI: https://doi.org/10.1007/BF02981643