Microbial metabolism of the environmental estrogen bisphenol A

Abstract

Preliminary microbial metabolism studies of bisphenol A (BPA) (1) on twenty six microorganisms have shown thatAspergillus fumigatus is capable of metabolizing BPA. Scale-up fermentation of 1 withA. fumigatus gave a metabolite (2) and its structure was established as bisphenol A-O-β-D-glucopyranoside (BPAG) based on spectroscopic analyses.

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Correspondence to Soon-Ho Yim or Hyun Jung Kim or Ik-Soo Lee.

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Yim, SH., Kim, H.J. & Lee, IS. Microbial metabolism of the environmental estrogen bisphenol A. Arch Pharm Res 26, 805–808 (2003). https://doi.org/10.1007/BF02980024

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Key words

  • Microbial metabolism
  • Bisphenol A
  • Bisphenol A-O-β-D-glucopyranoside
  • Aspergillus fumigatus