Abstract
Five phenolic compounds were isolated from 80% aq. acetone extract ofDuchesnea chrysantha. Their cytotoxicities were screened by the colorimetric tetrazolium assay (MTT assay). Gallic acid, methyl caffeate, protocatechuic acid and pedunculagin mildly inhibited the survival of PC14 and MKN45 human cancer cell. Brevifolin carboxylic acid showed a strong cytotoxic activity.
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Ihn Rhan Lee, Seung Won Wee, Yong Nam Han, Studies on the Pharmacological Actions and Biologically Active Components of Korean Traditional Medicone (VI). Tannins fromDuchesnea indica.Kor. J. Pharmacogn., 20(2), 110–116 (1989).
Ihn Rhan Lee, Seung Hye Hahn, Young Nam Han, Studies on the pharmacological actions and biologically active components of Korean traditional medicines. Anticancer macromolecular substances fromDuchesnea chrysantha herba.Saengyak Hakhoechi, 21(2), 186–92 (1990).
Ihn Rhan Lee, Young Hee Kim, Studies on the antitumor activity ofDuchesnea chrysantha herba.Arch. Pharm. Res, 9(1), 1–4 (1986).
Ihn Rhan Lee, Young Hee Kim, Gwang Ja Jeong, Studies on the pharmacological actions and biological active components of Korean traditional medicine.Yakhak Hoeji, 31(4), 230–235 (1987).
Margaret K. Seikel and W. E. Hillis, Hydrolysable Tannins ofEucalyptus delegatensis Wood.Phytochemistry, 9, 1115–1128 (1970).
Mukherjee K. S., Bhattacharya M. K., Ghosh P. K., Phytochemical investigation ofAesculus indica Linn. and a2Fragaria indica Andr.J. Indian Chem. Soc., 60(5), 507–508 (1983).
Stuart G., Chinese Materia Medica, Vegitable Kingdom, Shanghi, 178 (1991).
Takashi Tanaka, Gen-Ichiro Nonaka and Itsuo Nishioka. Tannins and Related Compounds. XI Revision of the Structures of Punicalin and Punicalagin, and Isolation and Characterization of 2-O-Galloylpunicalin from the Bark ofPunica granatum L.Chem. Pharm. Bull., 34 (2), 650–655 (1986).
Von Otto Th, Schmidt, Rudolf Eckert, Brevifolin carbonsaure, ihre optisch aktiven Formen und ihre Bindung an Glucose im Algarobina, einer neuen kristallisieten Verbindung aus Algarobilla. Eugenia Giinther und Hartmut Fiesser.Liebig Ann. Chem., 706, 804–212 (1967).
Won Sik Woo, Reserch method of natural product, p. 65, Mineumsa, 65 (1989).
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Lee, I.R., Yang, M.Y. Phenolic compounds fromDuchesnea chrysantha and their cytotoxic activities in human cancer cell. Arch. Pharm. Res. 17, 476–479 (1994). https://doi.org/10.1007/BF02979129
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DOI: https://doi.org/10.1007/BF02979129