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Gastrite granulomateuse

Granulomatous gastritis

Gastritis granulomatosa

  • Published:
Acta Endoscopica

Résumé

Le diagnostic de gastrite granulomateuse designe une lesion peu frequente, caracterisee par la presence de granulomes dans la muqueuse gastrique. Le diagnostic etiopathogenique n’est obtenu qu’en combinant Pexamen morphologique avec les resultats des investigations cliniques et biologiques. Les formes idiopathiques de la gastrite granulomateuse (69 %) comportent la maladie de Crohn (37 %), la sarcoidose (5 %) et la gastrite granulomateuse idiopathique (27 %).

La reaction aux corps etrangers (15 %), les infections (3 %), l’association avec les vasculites (3 %) et avec les lesions malignes (10 %) en tant que cause de gastrite granulomateuse, ne representent qu’une proportion largement inferieure.

Bien que le diagnostic de gastrite granulomateuse idiopathique soit fonde sur des donnees cliniques, radiologiques et morphologiques, l’entite elle-meme ne parait pas entierement homogene. La description recente de l’association gastrite granulomateuse etHelicobacter pylori, presente un grand interet et pose un probleme.

Summary

Granulomatous gastritis is an uncommon morphological diagnosis based upon the presence of granulomas in the gastric mucosa. An etiopathogenetic diagnosis can only be reached by combining the morphological examination with clinical and laboratory investigations.

The idiopathic forms of granulomatous gastritis (69 %), comprising Crohn’s disease (37 %), sarcoidosis (5 %) and idiopathic granulomatous gastritis (27 %), largely outnumber the foreign body reaction (15 %), infections (3 %), vasculitis associated (3 %) and malignancy associated forms (10 %). Although the diagnosis of idiopathic granulomatous gastritis is based upon clinical, radiological and morphological features, it seems this entity may not be entirely homogeneous. The recent description of granulomatous gastritis associated with Helicobacter pylori is of interest and raises questions.

Resumen

El diagnostico de gastritis granulomatosa designa una lesion poco frecuente, caracterizada por la presencia de granulomas en la mucosa gdstrica. El diagnostico etiopatogenico solo es posible si se combina el examen morfologico con los resultados de los estudios clinicos y biologicos. Las formas idiopdticas de la gastritis granulomatosa (69 %) comprenden la enfermedad de Crohn (37 %), la sarcoidosis (5 %) y la gastritis granulomatosa idiopdtica (27 %). Las reacciones a cuerpos extrahos (15 %), las infecciones (3 %) y la asociacion con vasculitis (3 %) y lesiones malignas (10 %) no representan sino una pequena proporcion.

Aun cuando el diagnostico de gastritis granulomatosa idiopdtica se basa en datos clinicos, radiologicos y morfoldgicos, la entidad no parece totalmente homogenea. La reciente descripcion de la asociacion gastritis granulomatosa-helicobacter pylori es de gran interes y ptantea, al mismo tiempo una nueva problemdtica.

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  1. Dept. of Pathology, Universi-taire Ziekenhuizen Leuven, U.Z. Sint-Rafael, Kapucijnenvoer 33, 3000, Leuven, Belgium

    N. Ectors, K. Geboes & V. Desmet

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Ectors, N., Geboes, K. & Desmet, V. Gastrite granulomateuse. Acta Endosc 20, 453–461 (1990). https://doi.org/10.1007/BF02977553

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