Abstract
Tōnin(Persicae Semen) is the herb medicine that contains amygdalin as a major ingredient. Amygdalin in water is decomposed into benzaldehyde, HCN, and glucose by emulsin, a hydrolysis enzyme in tōnin. A useful and practical method for the optimum extraction condition of amygdalin without enzymatic hydrolysis is required. The extraction yield of amygdalin of natural formula tō nin was 0.1% from crude powders, 1.4% from small pieces, 3.5% from half pieces and 2.4% from whole pieces. The extraction yield of amygdalin of outer shell-eliminated tō nin was 0.3% from crude powders, 1.4% from small pieces, and 3.5% from half pieces and whole pieces respectively. The extraction yield of amygdalin was most high when using the size larger than half.
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Hwang, EY., Lee, SS., Lee, JH. et al. Development of quantitative extraction method of amygdalin without enzymatic hydrolysis from tōnin(persicae semen) by high performance liquid chromatography. Arch Pharm Res 25, 453–456 (2002). https://doi.org/10.1007/BF02976601
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DOI: https://doi.org/10.1007/BF02976601