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Free radical scavengers from the heartwood ofJuniperus chinensis

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Abstract

The antioxidant activity ofJuniperus chinensis (Cupressaceae) was determined by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl). The methanolic extract ofJ. chinensis heartwood showed the strong antioxidant activity. The antioxidant activity ofn-BuOH soluble fraction was stronger than that of the others, and the fraction was subjected to purification by repeated silica gel and Sephadex LH-20 column chromatography. Quercetin, naringenin, taxifolin, aromadendrin and isoquercitrin were isolated from then-BuOH fraction. Their structures were elucidated by physico-chemical and spectroscopic studies.

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Correspondence to Dae Keun Kim.

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Lim, J.P., Song, Y.C., Kim, J.W. et al. Free radical scavengers from the heartwood ofJuniperus chinensis . Arch Pharm Res 25, 449–452 (2002). https://doi.org/10.1007/BF02976600

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