Abstract
Three varieties of methyl citrate and 1-methyl malate were isolated from the fruits ofOpuntia ficus-indica var.saboten Makino throughin vitro bioassay-guided isolation for the inhibition on monoamine oxidase(MAO). The IC50 values for MAO-B of 1-monomethyl citrate, 1,3-dimethyl citrate, trimethyl citrate and 1-methyl malate were 0.19, 0.23, 0.61 and 0.25 mM, respectively. However, on MAO-A, their inhibitions showed only marginal activity.
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Han, Y.N., Choo, Y., Lee, YC. et al. Monoamine oxidase B inhibitors from the fruits ofOpuntia ficus-indica var.saboten . Arch Pharm Res 24, 51–54 (2001). https://doi.org/10.1007/BF02976493
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DOI: https://doi.org/10.1007/BF02976493