Skip to main content

A New antioxidant monoterpene glycoside, α-benzoyloxypaeoniflorin fromPaeonia suffruticosa

Abstract

α-Benzoyloxypaeoniflorin (1), a new antioxidant monoterpene α-glycoside anomer was isolated fromPaeonia suffruticosa along with known compounds, β-benzoyloxypaeoniflorin (2), paeonolide, paeoniflorin and mudanpioside H. The structure of1 has been determined by comparing spectral data with those of β-benzoyloxypaeoniflorin(2). Compound1 exhibited moderately potent radical scavenging activity on DPPH radical.

This is a preview of subscription content, access via your institution.

References

  • Bax, A. and Sommers, M. F.,1H and13C assignments from sensitivity-enhanced detection of heteronuclear multiplebond connectivity by 2D multiple quantum NMR.J. Am. Chem. Soc., 108, 2093–2094 (1986).

    Article  CAS  Google Scholar 

  • Bax, A. and Subramanian, S. J., Sensitivity-enhanced twodimensional heteronuclear shift correlation NMR spectroscopy.J. Magn. Reson., 67, 565–569 (1986).

    CAS  Google Scholar 

  • Bock, K., Lundt, I. and Pederson, C., Assignment of anomeric structure to carbohydrates through geminal13C-H coupling constants.Tetrahedron Lett., 13, 1037–1040 (1973).

    Article  Google Scholar 

  • Ding, H.-Y., Wu, Y.-C., Jin, H.-C., Chan, Y.-Y., Wu, P.-L. and Wu, T.-S., Glycosides fromPaeonia suffruticosa.Chem. Pharm. Bull., 47, 652–655 (1999).

    CAS  Google Scholar 

  • Kariyone, T., Takahashi, M. and Takaishi, K., Synthesis and antimicrobial activity of acyl derivatives of heterocyclic amines.Yakugaku Zasshi, 79, 920–925 (1956).

    Google Scholar 

  • Kitakawa, T., Yoshikawa, M., Tsunaga, K. and Tani, T., Studies onMoutan cortex (II) on the chemical constituents.Shoyakugaku Zasshi, 33, 171–179 (1979).

    Google Scholar 

  • Morita, N., Shimizu, M. and Hayashi, T., Stomachic-digestans: drug group in the Chinese medicine formulation (10).The Journal of Traditional Sino-Japanese Medicine, 12, 86–92 (1991) and the literature cited therein.

    Google Scholar 

  • Murakami, N., Saka, M., Shimada, H., Matsuda, H., Yamahara, J. and Yoshikawa, M., New bioactive monoterpene glycosides fromPaeonia radix.Chem. Pharm. Bull., 44, 1279–1281 (1996).

    PubMed  CAS  Google Scholar 

  • Shibata, S., Inaba, M. and Aimi, N., The occurrence of paeoniflorin in the plants ofPaeonia spp.Shoyakugaku Zasshi, 20, 37–39 (1996).

    Google Scholar 

  • Uchyama, M., Suzuki, Y. and Fukuzawa, K., Biochemical studies of physiological function of tocopheronolactone.Yakugku Zasshi, 88, 678–683 (1968).

    Google Scholar 

  • Yen, G.-C. and Duh, P.-D., Scavenging effect of methanolic extracts of peanut hulls on free-radical and activeoxygen species.J. Agric. Food Chem., 42, 629–632 (1994).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Byoung Wook Choi.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Ryu, G., Park, E.K., Joo, J.H. et al. A New antioxidant monoterpene glycoside, α-benzoyloxypaeoniflorin fromPaeonia suffruticosa . Arch. Pharm. Res. 24, 105–108 (2001). https://doi.org/10.1007/BF02976476

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02976476

Key words