Abstract
Several quaternary pyridinium cephalosporin analogues were prepared and evaluatedin vitro for antibacterial activity against selected Gram-positive and Cram-negative organisms. Most of the synthesized analogues were either as effective or less effective against the tested bacterial organisms than the reference compounds, Cefpirome and Ceftazidime.
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Park, H., Choi, H., Jang, J. et al. Synthesis andin vitro antibacterial activity of cephalosporins with a pyridinium substituent carrying an isoxazole moiety at the C-3 position. Arch. Pharm. Res. 24, 89–94 (2001). https://doi.org/10.1007/BF02976473
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DOI: https://doi.org/10.1007/BF02976473