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Aromatase inhibitors fromIsodon excisus var.coreanus

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Abstract

The diethyl ether extract ofIsodon excisus var.coreanus exhibited significant inhibitory activity in aromatase assay. Bioactivity-guided fractionation of the extract led to the isolation of three active compounds: inflexin (ent-1α-hydroxy-3β,6a-diacetoxykaur-16-en-11,15-dione) (1), ursolic acid (2), and ursolic acid 3-O-acetate (3).

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Correspondence to Hyeh-Jean Jeong.

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Jeong, HJ., Chang, L.C., Kim, HK. et al. Aromatase inhibitors fromIsodon excisus var.coreanus . Arch Pharm Res 23, 243–245 (2000). https://doi.org/10.1007/BF02976453

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  • DOI: https://doi.org/10.1007/BF02976453

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