Abstract
Thiocarboxamidocinnamonitrile derivatives2 a–f reacted with 3-aminopyrazole derivatives3 a–c to give the pyrazole[3,2-b]pyrimidine derivatives6 a–p. Compounds6 a–p were used as starting material for syntheses of several heterocylic coompounds. Dehydrogenation of6 gave pyrazole[3,2-b]pyrimidines10 a–d while its reaction with diethyl oxalate gave11. Reactions of6 with formic acid gave pyrazolopyrimidines17 a–j, and pyrazolopyrimidopyrimidinoes18 a–j.
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Attaby, F.A., Eldin, S.M. Reactions of 3-aminopyrazole derivatives with cyanothioacetamide and its derivatives: Synthesis and reactions of several new pyrazole and pyrazole[3,2-b]pyrimidine derivatives. Arch. Pharm. Res. 20, 330–337 (1997). https://doi.org/10.1007/BF02976195
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DOI: https://doi.org/10.1007/BF02976195