Abstract
A synthetic procedure for the preparation of indole-2,3-dione derivatives6 as a potential NMDA receptor glycine site antagonist with improved pharmacological profile compared with 2-carboxyindole derivative5, starting from readily available 3,5-dichloraniline (7), is described.
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Hwang, KJ., Lee, Ts. Synthesis of 4,6-dichloro-3-[(1-N-arylaminocarbonyl)-hydrazono]-1,3-dihydro-indole-2-one as a potential NMDA receptor glycine site antagonist. Arch Pharm Res 23, 112–115 (2000). https://doi.org/10.1007/BF02975498
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DOI: https://doi.org/10.1007/BF02975498