Abstract
4-Bromoacetophenone-pyrrolecarboxamide conjugates were designed and synthesized as photoinducible DNA cleaving agents which can generate monophenyl radicals capable of causing the hydrogen atom abstraction which initiates the scission of DNA.
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Jeon, R., Wender, P.A. Design and synthesis of new DNA photocleavers, 4′-bromoacetophenone-pyrrolecarboxamide hybrid compounds. Arch Pharm Res 23, 585–588 (2000). https://doi.org/10.1007/BF02975245
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DOI: https://doi.org/10.1007/BF02975245