Abstract
Phytochemical investigation of the MeOH extract of the root barks ofCudrania tricuspidata Bureau (Moraceae), as guided by hepatoprotective activityin vitro, furnished four isoprenylated xanthones, cudratricusxanthone A (1), cudraxanthone L (2), cudratricusxanthone E (3), and macluraxanthone B (4). All of these compounds showed the significant hepatoprotective effect on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. Compounds1, 2, and4 also exhibited the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.
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Tian, YH., Kim, HC., Cui, JM. et al. Hepatoprotective constituents ofcudrania tricuspidata . Arch Pharm Res 28, 44–48 (2005). https://doi.org/10.1007/BF02975134
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DOI: https://doi.org/10.1007/BF02975134