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HIV-1 integrase inhibitory phenylpropanoid glycosides fromClerodendron trichotomum

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  • Medicinal Chemistry & Natural Products
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An Erratum to this article was published on 01 December 2001

Abstract

Seven phenylpropanoid glycosides named acteoside (1), acteoside isomer (2), leucosceptoside A (3), plantainoside C (4), jionoside D (5), martynoside (6), and isomartynoside (7) were isolated fromClerodendron trichotomum. Compounds1 and2 showed potent inhibitory activities against HIV-1 integrase with IC50 values of 7.8 ± 3.6 and 13.7 ± 6.0 μM, respectively.

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Authors and Affiliations

  1. Division of Life Sciences, Korea Institute of Science & Technology, P.O. Box 131, 130-650, Cheongryang, Seoul, Korea

    Hyoung Ja Kim, Eun-Rhan Woo, Dong Jin Hwang, Hokoon Park & Yong Sup Lee

  2. College of Pharmacy, Chosun University, 501-759, Kwangju, Korea

    Eun-Rhan Woo

  3. Department of Biotechnology, Chung Ang University, 456-756, An-Sung, Korea

    Cha-Gyun Shin

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  1. Hyoung Ja Kim
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  2. Eun-Rhan Woo
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  3. Cha-Gyun Shin
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  4. Dong Jin Hwang
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  5. Hokoon Park
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  6. Yong Sup Lee
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Correspondence to Yong Sup Lee.

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An erratum to this article is available at http://dx.doi.org/10.1007/BF02975176.

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Kim, H.J., Woo, ER., Shin, CG. et al. HIV-1 integrase inhibitory phenylpropanoid glycosides fromClerodendron trichotomum . Arch Pharm Res 24, 286–291 (2001). https://doi.org/10.1007/BF02975093

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  • DOI: https://doi.org/10.1007/BF02975093

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